Navigation Links
Genomics throws species definition in question for microbes

Until a decade ago, scientists categorized microorganisms almost exclusively by their physical characteristics: how they looked, what they ate, and the by-products they produced. With the advent of genomic sequencing and genetic analysis in the 1990s, our understanding of the relationships between different microorganisms fundamentally changed. In light of this new knowledge, what exactly is the definition of a microbial species, and how should microbiologists be categorizing microorganisms? These questions are the focus of a new report released by the American Academy of Microbiology (AAM) entitled Reconciling Microbial Systematics and Genomics.

"It is clear that the current system for designating microbial species is somewhat functional, but inadequate in many ways. It is unclear whether this system should be replaced or renovated," says Richard Roberts of New England Biolabs, one of the authors of the report.

The report is the result of a colloquium convened by the AAM in September 2006. Participants with expertise in microbial taxonomy, systematics, ecology, physiology and other areas described the history of microbial taxonomy, the state of the field today, and how work in the field should proceed in the future. The report is a record of their comments and recommendations.

In the late 1800s, in order to make sense of the vast diversity of microbiological organisms, microbial taxonomists developed a system of placing microorganisms into categories in which each organism was granted a "genus" and "species" designation. At the time, physical (or phenotypic) properties were the only means of describing microorganisms, so the system was based on measurable and observable characteristics of the organisms, not genetic traits.

In the late 20th century, molecular biology uncovered the genetic relationships between microorganisms, and some of the secrets of microbes that had yet to be cultured in the lab (and hence phenoty pically characterized) were revealed.

"Much of this new knowledge was incorporated into species descriptions, but difficulties in classification persisted and novel issues arose," says Roberts. "Conflicts exist between phenotypic and phylogenetic information, the means for classifying non-cultured microbes are limited under the current paradigm, and microbial species do not always demonstrate the phenotypic or genetic cohesiveness expected of them. For these reasons and others it has become clear that the species classification framework in use today is not capable of fully portraying and organizing microbial diversity."

The report contains an in-depth review of the myriad issues and conflicts involved in the classification of microbes in the post-genomic era, including a discussion on the definition of the term "species." It ends with a set of specific recommendations including, but not limited to:

  • The establishment of a subcommittee within the International Committee on Systematics of Prokaryotes to consider a paradigm shift in the species definition.
  • The need for more thorough study of the mechanisms of speciation before a more meaningful and practical species theory can be developed.
  • The need for more comprehensive and systematic data to uncover whether microorganisms are organized into robust, definable, biologically meaningful clusters that adhere to the concept of species.
  • The acquisition of draft-quality genome sequences for all type strains to help advance the integration of genomic information into our understanding of microbial diversity and enable researchers to map phenotypes to genomes.

'"/>

Source:American Society for Microbiology


Related biology news :

1. Advancements In Genomics Foster Deep Sea Discoveries
2. Ariadne Genomics Announces the Release of PathwayStudio?Central, Client-Server Software for Biological Pathway Analysis
3. Genomics researchers discover protein deficit that causes drug toxicity
4. Genomics-based vaccine could prevent deadly cattle disease
5. New species from old data
6. Same mutation aided evolution in many fish species, Stanford study finds
7. Fibril Shape Is The Basis Of Prion Strains And Cross-species Prion Infection
8. Reservoirs may accelerate the spread of invasive aquatic species, researchers say
9. Small species back-up giant marsupial climate change extinction claim
10. Aggressive aquatic species invading Great Lakes
11. Bush, Cheney and Rumsfeld are now species of slime-mold beetles -- but strictly in homage
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/20/2016)... , May 20, 2016  VoiceIt is ... partnership with VoicePass. By working together, ... experience.  Because VoiceIt and VoicePass take slightly different ... engines increases both security and usability. ... excitement about this new partnership. "This ...
(Date:5/9/2016)... Elevay is currently known as ... for high net worth professionals seeking travel for work ... world, there is still no substitute for a face-to-face ... your deal with a firm handshake. This is why ... of citizenship via investment programs like those offered by ...
(Date:4/28/2016)... Sweden , April 28, 2016 First ... M (139.9), up 966% compared with the first quarter of 2015 ... profit totaled SEK 589.1 M (loss: 18.8) and the operating margin ... 7.12 (loss: 0.32) Cash flow from operations was SEK ... The 2016 revenue guidance is unchanged, SEK 7,000-8,500 M. ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... GUELPH, ON , June 27, 2016 /PRNewswire/ - BIOREM ... it has been advised by its major shareholders, Clean ... LP, United States based venture ... common shares of Biorem (on a fully diluted, as ... for the disposition of their entire equity holdings in ...
(Date:6/27/2016)... N.C. (PRWEB) , ... June 27, 2016 , ... ... commercial operations for Amgen, will join the faculty of the University of ... as adjunct professor of strategy and entrepreneurship at UNC Kenan-Flagler, with a focus ...
(Date:6/24/2016)... ... June 24, 2016 , ... While the majority of ... the Cary 5000 and the 6000i models are higher end machines that use the ... of the spectrophotometer’s light beam from the bottom of the cuvette holder. , ...
(Date:6/23/2016)... 2016 /PRNewswire/ - FACIT has announced the creation ... biotechnology company, Propellon Therapeutics Inc. ("Propellon" or "the ... a portfolio of first-in-class WDR5 inhibitors for the ... WDR5 represent an exciting class of therapies, possessing ... for cancer patients. Substantial advances have been achieved ...
Breaking Biology Technology: