Navigation Links
Genome sequencing is for ecologists, too

An organism widely used for genetics-versus-environment studies has joined the panoply of mice, rats, dogs, humans and other species whose entire genomes have been sequenced.

At the Daphnia Genomics Consortium's annual meeting in Bloomington this week, Indiana University and Joint Genome Institute scientists announced they've completed a "shotgun" sequence for Daphnia pulex, or the water flea, as it's better known to high school biology students.

"Daphnia is important to the environmental sciences, where the goal is to understand the complexities of ecosystems by getting a handle on how species in natural settings respond genetically to their environments," said Daphnia Genomics Project leader John Colbourne. "Ecologists and evolutionary biologists would also want to learn more about how genetic variation is important for adaptation and how populations survive in a changing world."

Colbourne is a founding member of the Daphnia Genomics Consortium and the genomics director of the Center for Genomics and Bioinformatics at IU Bloomington.

The U.S. Department of Energy and the National Science Foundation funded the Daphnia project. Most of the sequencing work was done at DOE's Joint Genome Institute Production Genomics Facility in Walnut Creek, Calif.

Shotgun sequencing involves breaking a whole genome into smaller, more digestible DNA segments, then sequencing each one. The Daphnia genome was sequenced over eight times to ensure better coverage of all 12 pairs of chromosomes.

Daphnia's short generation time and small genome (a mere 200 million base pairs) makes it an ideal organism for laboratory and field studies of how environments influence -- and how they're influenced by -- an organism's genetics. The animals are common in lakes and ponds and have been used to monitor the health of aquatic environments. Members of the species can reproduce both with and without sex, which has important implications in evolutionary b iology and ecology.

Species whose genomes have been sequenced are generally used for experiments in physiology and in developmental and cell biology, but rarely in ecology. Scientists are eager to exploit genomic technologies and genomic experimental approaches that have already revolutionized research in the human health sciences, with the goal of diagnosing the state of aquatic environments.

Despite their common name, water fleas are not insects but crustaceans, like lobsters and crabs. Daphnia is the first crustacean genome to be sequenced. Information from its genome will help biologists make sense of similarities and differences among the intensively studied genetic models of insects, which are evolutionary relatives of crustaceans.

"The genome sequences are being completed for several insects because they are important model organisms -- like fruit flies -- or because they are important in disease or agriculture," said Jeffrey Boore, head of the evolutionary genomics program at the Joint Genome Institute. "And the Daphnia genome sequence will illuminate all of this by allowing us to infer the ground state from which the insect genomes evolved."


'"/>

Source:Indiana University


Related biology news :

1. Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer
2. Affymetrix Unveils Plans to Double Plant and Animal Genome Microarray Offering
3. Genome-wide mouse study yields link to human leukemia
4. New Study from Affymetrix Laboratories Points to Changing View of How Genome Works
5. Multiple Campylobacter Genomes Sequenced
6. Analysis Of Human Genome To Predict The Development Of Illnesses
7. Whole genome promoter mapping - Human Genome Project v2.0?
8. Genome study of beneficial microbe may help boost plant health
9. Candida albicans Genome Fully Annotated
10. Genome Sequence for Haemophilus Influenzae Completed
11. NHGRI Selects 13 More Organisms for Genome Sequencing
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/11/2017)... April 11, 2017 Crossmatch®, a globally-recognized ... solutions, today announced that it has been awarded ... Projects Activity (IARPA) to develop next-generation Presentation Attack ... "Innovation has been a driving force within ... will allow us to innovate and develop new ...
(Date:4/5/2017)... April 5, 2017  The Allen Institute for Cell ... Explorer: a one-of-a-kind portal and dynamic digital window into ... data, the first application of deep learning to create ... cell lines and a growing suite of powerful tools. ... these and future publicly available resources created and shared ...
(Date:3/30/2017)... ANGELES , March 30, 2017  On April ... Hack the Genome hackathon at Microsoft,s ... exciting two-day competition will focus on developing health and ... Hack the Genome is the ... been tremendous. The world,s largest companies in the genomics, ...
Breaking Biology News(10 mins):
(Date:9/18/2017)... Sept. 18, 2017   Montrium , a growing leader in ... new partnership with a groundbreaking non-profit research organization, Multidisciplinary Association ... ... studies for PTSD ... granted Breakthrough Therapy Designation to MDMA for the treatment of Posttraumatic ...
(Date:9/14/2017)... ... September 14, 2017 , ... ... Services, formally introduces its flexible scientist program (FSP)-- a flexible business approach ... The FSP, which combines SSCI’s extensive project-based analytical and solid-state chemistry services ...
(Date:9/14/2017)... , ... September 14, 2017 , ... ... Freedom Lumbar Disc case in Australia. Dr. Steven Yang completed the procedure on ... a result of a degenerative lumbar disc at level L5-S1. The patient failed ...
(Date:9/13/2017)... ... September 13, 2017 , ... AMRI, ... industry to improve patient outcomes and quality of life for more than 25 ... named a US expert to the International Standards Organization/Technical Committee 194: Biological ...
Breaking Biology Technology: