Navigation Links
Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer

he genome sequenced is allowing the development of "new diagnostic tests that help distinguish the most deadly substrains of the parasite."

Dr. Alok Bhattacharya, a collaborator at the School of Life Sciences at India's Jawaharlal Nehru University, says having the genome sequence "will help to identify new drug and vaccine targets" and also may help researchers understand why the disease hits only a small fraction of those who are hosts to the parasite. "Intestinal infections are one of the major health problems in developing countries and the number of people who are infected with amoeba cysts is enormous," he says.

Typically, those cysts are transmitted when people ingest contaminated food or water. The disease can cause liver damage but more often causes dysentery, a severe diarrhea that is often associated with blood in the feces. Unchecked, the diarrhea associated with the disease can be fatal, especially in children. One field study in Bangladesh found that E. histolytica infection occurred at least once in 80 percent of 300 children. Over a period of four years, about a third of the children suffered from amebic colitis, an ulceration of the stomach lining.

Petri says the genome data will help researchers find more about what makes some people innately resistant to infection by E. histolytica, and what acquired immune responses can protect people from re-infection. Says Petri: "The genome project has spawned rapid discovery of the parasite's mechanisms for replication, gene expression, motility, metabolism, and the killing of host cells."

###

The Institute for Genomic Research (TIGR) is a not-for-profit research institute based in Rockville, Maryland. TIGR, which sequenced the first complete genome of a free-living organism, has been at the forefront of the genomic revolution since the institute was founded in 1992. The Institute's scientists conduct research involving the structural, functional, and comparative analysi
'"/>

Source:The Institute for Genomic Research


Page: 1 2 3 4 5

Related biology news :

1. Affymetrix Unveils Plans to Double Plant and Animal Genome Microarray Offering
2. Genome-wide mouse study yields link to human leukemia
3. New Study from Affymetrix Laboratories Points to Changing View of How Genome Works
4. Multiple Campylobacter Genomes Sequenced
5. Analysis Of Human Genome To Predict The Development Of Illnesses
6. Whole genome promoter mapping - Human Genome Project v2.0?
7. Genome study of beneficial microbe may help boost plant health
8. Candida albicans Genome Fully Annotated
9. Genome Sequence for Haemophilus Influenzae Completed
10. NHGRI Selects 13 More Organisms for Genome Sequencing
11. First Whole Genome Map of Genetic Variability in Parkinson’s Disease
Post Your Comments:
(Date:3/23/2015)... 23, 2015 NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" ... growing mobile commerce market, announces its biometric payment technology, the ... CNBC television starting March 30 th . ... New York markets. ... excited about our new ad campaign following the recent initial ...
(Date:3/20/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/vkzvcs/iris_biometrics ) ... Global Strategic Business Report" report to their offering. ... in US$ Thousands. The report provides separate comprehensive analytics for ... , Europe , Asia-Pacific ... Latin America . Annual estimates and ...
(Date:3/17/2015)... 2015 Emotient, the leader in facial ... general availability of Emotient Analytics , the ... of facial expressions. The system analyzes videos of ... and services. It delivers audience response metrics - ... as derived from facial evidence of emotional states. ...
Breaking Biology News(10 mins):NXT-ID's Wocket Smart Wallet to Launch New CNBC Regional TV Ad Campaign 2NXT-ID's Wocket Smart Wallet to Launch New CNBC Regional TV Ad Campaign 3Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 2Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 3Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 4Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 5New Emotient Web Service Measures Audience Response Using On-Demand Facial Expression Analysis 2New Emotient Web Service Measures Audience Response Using On-Demand Facial Expression Analysis 3New Emotient Web Service Measures Audience Response Using On-Demand Facial Expression Analysis 4
... a specific gene plays a role in the weight-gain response ... animal study suggests that blocking this gene could one day ... disorders, such as diabetes and liver damage, in humans. ... production of this gene, called protein kinase C beta (PKC ...
... University of Liverpool (UoL) have secured a 1.4 million project ... malaria. The project, funded by the Wellcome Trust, aims ... a novel enzyme in the respiratory chain of Plasmodium ... enzyme within the parasite is not found in humans, thereby ...
... Cardiovascular Research Institute, Colchester, Vermont have found that ... inhibitor type-1 (PAI-1) is profibrotic. The results, ... Experimental Biology and Medicine , implicate PAI-1 ... 2 diabetes, as a factor contributing to the ...
Cached Biology News:Researchers uncover 'obesity gene' involved in weight gain response to high-fat diet 2Researchers uncover 'obesity gene' involved in weight gain response to high-fat diet 3LSTM and UoL secure £1.4m ($2m) to develop new 'magic bullet' antimalarial drug 2Plasminogen activator inhibitor type-1 -- a potential link between heart failure and diabetes 2
(Date:4/16/2015)... LAUSANNE , Switzerland ... Debiopharm International SA (Debiopharm), part of Debiopharm Group ™ ... prescription drugs that target unmet medical needs ... that preclinical data on the investigational compounds ... inhibitor) will be presented at the 2015 ...
(Date:4/16/2015)... Fairleigh Dickinson University ( FDU ... become the Executive Director of the Rothman Institute ... kick-off of the Initiative for Patient Centered Innovation ... under the Rothman Institute of Innovation and Entrepreneurship ... collaboration with FDU’s School of Pharmacy’s Center for ...
(Date:4/16/2015)... Washington (PRWEB) April 16, 2015 ... Applied Cancer Science and Resolution Bioscience, Inc. today ... to co-develop a novel, blood-based, clinic ready, Next ... cancer (NSCLC). The collaboration is the first to ... RET, and ROS1 fusions in blinded plasma samples ...
(Date:4/16/2015)... 2015 CCI Global Channel Management, the ... planning management software for major tech and telecom vendors, ... survey of channel vendor programs in software, hardware, and ... How the top IT vendors in each segment ... coming year. , Assessment of the state ...
Breaking Biology Technology:Debiopharm International SA Announces Results of 2 Key Oncology Programs at 2015 AACR Conference 2Debiopharm International SA Announces Results of 2 Key Oncology Programs at 2015 AACR Conference 3Dr. Joseph V. Gulfo Named Executive Director of Fairleigh Dickinson University’s Rothman Institute to Spearhead New Initiative for Patient-Centered Innovation (iPCI) 2Dr. Joseph V. Gulfo Named Executive Director of Fairleigh Dickinson University’s Rothman Institute to Spearhead New Initiative for Patient-Centered Innovation (iPCI) 3Resolution Bioscience announces successful collaboration on a novel, non-invasive, targeted NGS test for lung cancer 2Resolution Bioscience announces successful collaboration on a novel, non-invasive, targeted NGS test for lung cancer 3CCI’s Channel Program Study Reveals 40% of IT Vendor Channel Staff Lack Adequate Access to Program and Partner Data 2CCI’s Channel Program Study Reveals 40% of IT Vendor Channel Staff Lack Adequate Access to Program and Partner Data 3
... Researchers at Rensselaer Polytechnic Institute and Polyset ... that could lead to dramatic cost savings and ... packaging. , Along with allowing enhanced performance and ... material, called polyset epoxy siloxane (PES), should also ...
... Jan. 28 MedPredict has published,"Thought Leader Insight ... insight for pharma and biotech companies with a,stake ... this disease area., "Given the size of ... for long-term disease control, it is not surprising ...
... Breathing Resistance,Exerciser has successfully accomplished the crossover ... the respiratory therapy market for,COPD patients. Jorge ... the most compact (4") breathing exerciser, originally ... size portable respiratory,exerciser to increase lung capacity ...
Cached Biology Technology:New polymer could improve semiconductor manufacturing, packaging 2New Report Tackles the Changing Landscape for Alzheimer's Diagnostics and Treatments 2It's Good News for The Lungs! 2
This monoclonal antibody specifically recognizes Y. pestiscapsular F1 antigen. It does not cross-react with Y. pseudotuberculosisor Y. enterocolitica....
... formulated for covering tissue sections and cell preparations ... alcohol insoluble end products. UltraMount Plus ... Red or AEC that require an aqueous mounting ... DAB. No heating is required prior to use. ...
This monoclonal antibody specifically recognizes Y. pestiscapsular F1 antigen. It does not cross-react with Y. pseudotuberculosisor Y. enterocolitica....
... III is intented for ... PBMCs (or lysed whole ... intracellular kinases and appropriate ... Applications: Intracellular Staining (Flow) ...
Biology Products: