Navigation Links
Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer

he genome sequenced is allowing the development of "new diagnostic tests that help distinguish the most deadly substrains of the parasite."

Dr. Alok Bhattacharya, a collaborator at the School of Life Sciences at India's Jawaharlal Nehru University, says having the genome sequence "will help to identify new drug and vaccine targets" and also may help researchers understand why the disease hits only a small fraction of those who are hosts to the parasite. "Intestinal infections are one of the major health problems in developing countries and the number of people who are infected with amoeba cysts is enormous," he says.

Typically, those cysts are transmitted when people ingest contaminated food or water. The disease can cause liver damage but more often causes dysentery, a severe diarrhea that is often associated with blood in the feces. Unchecked, the diarrhea associated with the disease can be fatal, especially in children. One field study in Bangladesh found that E. histolytica infection occurred at least once in 80 percent of 300 children. Over a period of four years, about a third of the children suffered from amebic colitis, an ulceration of the stomach lining.

Petri says the genome data will help researchers find more about what makes some people innately resistant to infection by E. histolytica, and what acquired immune responses can protect people from re-infection. Says Petri: "The genome project has spawned rapid discovery of the parasite's mechanisms for replication, gene expression, motility, metabolism, and the killing of host cells."

###

The Institute for Genomic Research (TIGR) is a not-for-profit research institute based in Rockville, Maryland. TIGR, which sequenced the first complete genome of a free-living organism, has been at the forefront of the genomic revolution since the institute was founded in 1992. The Institute's scientists conduct research involving the structural, functional, and comparative analysi
'"/>

Source:The Institute for Genomic Research


Page: 1 2 3 4 5

Related biology news :

1. Affymetrix Unveils Plans to Double Plant and Animal Genome Microarray Offering
2. Genome-wide mouse study yields link to human leukemia
3. New Study from Affymetrix Laboratories Points to Changing View of How Genome Works
4. Multiple Campylobacter Genomes Sequenced
5. Analysis Of Human Genome To Predict The Development Of Illnesses
6. Whole genome promoter mapping - Human Genome Project v2.0?
7. Genome study of beneficial microbe may help boost plant health
8. Candida albicans Genome Fully Annotated
9. Genome Sequence for Haemophilus Influenzae Completed
10. NHGRI Selects 13 More Organisms for Genome Sequencing
11. First Whole Genome Map of Genetic Variability in Parkinson’s Disease
Post Your Comments:
(Date:12/3/2014)... , Dec. 2, 2014 As part of ... Inception Technologies is pleased to announce the release of ... customers to collect the workforce data that they need. ... have been left by existing readers. Many such devices ... connectivity and modern technology. Older models force users to ...
(Date:11/21/2014)... 20, 2014 Strict laws against distracted driving ... the North American and European automotive sector towards gesture ... recognition systems that are intuitive and able to retrieve ... industry. New analysis from Frost & ... in Europe and ...
(Date:11/18/2014)... 18, 2014  The Secure Identity & Biometrics ... jointly announce the formation of The Airport Entry ... Identity and Biometric Entry and Exit Solutions ... official support from BORDERPOL, the international non-profit organization ... provide expertise regarding border security, traveler and migration ...
Breaking Biology News(10 mins):Inception Technologies to Release New Biometric Reader 2Gesture Recognition Intensifies with the Rise of In-car Smartphone Integration, Says Frost & Sullivan 2Gesture Recognition Intensifies with the Rise of In-car Smartphone Integration, Says Frost & Sullivan 3Gesture Recognition Intensifies with the Rise of In-car Smartphone Integration, Says Frost & Sullivan 4Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 2Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 3
... WHO: ,The American Association of Pharmaceutical Scientists ... 12,000 members employed in industry, academia, government and ... provides a dynamic international forum for the exchange ... to public health. AAPS offers timely scientific programs, ...
... CHAPEL HILL A new study shows that parents are ... if it,s color-coded, like a traffic light, than the standard ... of BMI from doctor to parent could lead to parents ... help them make important lifestyle changes," says Eliana Perrin, M.D., ...
... to a novel approach to the treatment of a devastating ... Center at Houston report they are the first to link ... Findings appear online and will be in the January 2010 ... of The Federation of American Societies for Experimental Biology. ...
Cached Biology News:AAPS and PhRMA co-sponsor stability workshop 2UNC study: Color-coded chart improves parents' understanding of body mass index 2UT scientists discover link between protein and lung disease 2
(Date:12/24/2014)... (PRWEB) December 23, 2014 Nashville Fertility ... was elected treasurer for the American Society for Reproductive ... knowledge and research in reproductive medicine. In his ... seat on the executive board and will have a ... Dr. Hill has actively supported ASRM since 1984 when ...
(Date:12/24/2014)... 2014 PharmaBoardroom,s new report, ... and available for free download , digs deep into ... growth in the sector today. One area where ... been in developing a homegrown pharmaceutical manufacturing base, even if ... remains some way off. A cursory comparison with neighboring ...
(Date:12/22/2014)... , Dec. 22, 2014   ... a developer of pathogen-specific therapies for serious ... protecting the microbiome, today announced positive topline ... 1a clinical trial of SYN-004, the Company,s ... of Clostridium difficile (C. difficile) ...
(Date:12/22/2014)... The American Journal of ... research, reviews and editorials addressing developments and pathways ... published a provocative article exploring the role of ... potential treatment of prostate cancer. , The ... the possibility that there could be a connection ...
Breaking Biology Technology:Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 2Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 3PharmaBoardroom Releases New Algeria Pharmaceuticals Report 2PharmaBoardroom Releases New Algeria Pharmaceuticals Report 3Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 2Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 3Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 4Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 5Prostate Cancer Experts Dissect the Role of Follicle-stimulating Hormone in the Development, Progression and Potential Treatment of Prostate Cancer 2Prostate Cancer Experts Dissect the Role of Follicle-stimulating Hormone in the Development, Progression and Potential Treatment of Prostate Cancer 3Prostate Cancer Experts Dissect the Role of Follicle-stimulating Hormone in the Development, Progression and Potential Treatment of Prostate Cancer 4
... assets to stimulate growth , ,MADISON - More than ... Tuesday to hear Madison Mayor Dave Cieslewiczs plan for the ... a model for a forward economy, a 38-page ... as a vision for how Madisons public and private sectors ...
... RedPrairie Corporation Friday announced the availability ... services designed to ensure major retailer and Department of ... to meet each companys RFID implementation environment and schedule. ... foundation for the three others, is RFID Data Manager. ...
... bacteria that causes tuberculosis (TB) and leprosy are notoriously ... held in check for the past 50 years by ... therapy. , ,Now, however, a new chink has been ... diseases difficult to treat. The discovery, reported today (May ...
Cached Biology Technology:Madisons visionary plan for a healthy economy 2Madisons visionary plan for a healthy economy 3RedPrairie announces RFID 360 compliance software 2UW discovery could lead to new TB treatments 2UW discovery could lead to new TB treatments 3
Mouse monoclonal antibody raised against a partial recombinant ST3GAL2. NCBI Entrez Gene ID = ST3GAL2...
... Apoptosis is an evolutionarily conserved form of ... process. The central component of this ... called caspases. These enzymes participate in ... in response to pro-apoptotic signals and result ...
... DNA Visualizer Extraction Kit is manufactured for ... DNA damage byexposure to UV light. The ... is often used for DNA-cloning work. The ... bromide and exposure of UV light damages ...
...
Biology Products: