Navigation Links
Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer

The genome sequence of the parasitic amoeba Entamoeba histolytica, a leading cause of severe diarrheal disease in developing countries, includes an unexpectedly complex repertoire of sensory genes as well as a variety of bacterial-like genes that contribute to the organism's unique biology.

The report, which appears in the February 24 issue of Nature, presents the first genome-wide study of an amoeba. It is also the first genome sequence to be published from this class of amitochondrial human pathogens.

The analysis reveals the degradation of the E. histolytica genome in its transition from a free-living organism into a parasite of the human gut. At the same time, scientists also cataloged the retention and expansion of some gene families characteristic of more complex organisms.

Detailing the first systematic study of relatively recent horizontal gene transfer into a protist, scientists report evidence in the DNA sequence that E. histolytica likely picked up a significant number of its metabolic genes from bacterial co-inhabitants of the human gut. Identification of these genes sheds new light on the unusual shared biology between the parasitic amoeba and anaerobic gut bacteria.

The E. histolytica genome sequence is expected to help in the development of new vaccines as well as diagnostic tests that can distinguish the amoeba's most deadly strains. The parasite infects an estimated 50 million people and causes as many as 100,000 deaths a year -- second only to malaria as a cause of morbidity and mortality from a protist. The disease caused by E. histolytica is called amebiasis.

The sequencing of E. histolytica was a collaborative effort led by The Institute for Genomic Research (TIGR) in Rockville, MD, and by the Wellcome Trust Sanger Institute in the U.K. The project was supported by grants from the National Institute of Allergy and Infectious Diseases (NIAID), which is part of the National Institutes of Health, and from the
'"/>

Source:The Institute for Genomic Research


Page: 1 2 3 4 5

Related biology news :

1. Affymetrix Unveils Plans to Double Plant and Animal Genome Microarray Offering
2. Genome-wide mouse study yields link to human leukemia
3. New Study from Affymetrix Laboratories Points to Changing View of How Genome Works
4. Multiple Campylobacter Genomes Sequenced
5. Analysis Of Human Genome To Predict The Development Of Illnesses
6. Whole genome promoter mapping - Human Genome Project v2.0?
7. Genome study of beneficial microbe may help boost plant health
8. Candida albicans Genome Fully Annotated
9. Genome Sequence for Haemophilus Influenzae Completed
10. NHGRI Selects 13 More Organisms for Genome Sequencing
11. First Whole Genome Map of Genetic Variability in Parkinson’s Disease
Post Your Comments:
(Date:7/11/2014)... July 10, 2014---A team of researchers from The Chinese ... identified a gene of wild soybean linked to salt ... grow in saline soil. This study published online in ... unveil novel genomic information for crop improvement. , Soybean ... domestication and human selection, cultivated soybeans have less genetic ...
(Date:7/11/2014)... July 11, 2014 Researchers have pioneered ... images. The new technology, called Virtual Finger, allows ... structures like neurons and synapses using the flat ... technology makes 3D imaging studies orders of magnitude ... an unprecedented level across many areas of experimental ...
(Date:7/11/2014)... receptor type 1 can inhibit voltage-gated calcium ... neurotransmitter release. However, some scholars demonstrated that ... Ca2+ influx and increase neurotransmitter release. Dr. ... Affiliated to Tongji Medical College, Huazhong University ... cell voltage-clamp and calcium imaging in cultured ...
Breaking Biology News(10 mins):BGI reports a novel gene for salt tolerance found in wild soybean 2Virtual finger enables scientists to navigate and analyze complex 3D images 2
... MURCIA, SPAINSalt can have drastic effects on the ... that salinity renders an about one-third of the world,s ... salinity can cause ion toxicity, osmotic stress, mineral deficiencies, ... stress can even cause plants to adjust their water ...
... of modern humans like more than 50,000 years ago? ... Stone Age engravings are the subjects of a good deal ... journal Science , an international team of researchers report ... could place the use of herbal medicines much earlier than ...
... growing in popularity as more growers turn to strip-till. However, ... worth. A new University of Illinois study revealed ... soybean. However, the results showed no difference in yield between ... corn, not soybean," said Fabian Fernandez, U of I assistant ...
Cached Biology News:Salt-tolerant crops show higher capacity for carbon fixation 2Earliest known bug-repellant plant bedding found at South African rock shelter 2Earliest known bug-repellant plant bedding found at South African rock shelter 3Earliest known bug-repellant plant bedding found at South African rock shelter 4Strip-till improves nutrient uptake and yield 2
(Date:7/10/2014)... Poway, CA (PRWEB) July 10, 2014 Robert ... Regenerative Veterinary Medicine company, is proud to announce the relaunch ... Pets, launching with a new series called “ What are ... to give an honest and straightforward foundation in the basics ... an educated decision on the right type of treatment when ...
(Date:7/10/2014)... CROWN POINT, Ind. , July 10, ... recently expanded its use of capnography for ... a growing group of healthcare leaders in ... Capnography measures how effectively patients are breathing ... respiratory depression occurs. By measuring the amount ...
(Date:7/10/2014)... Research and Markets ( http://www.researchandmarkets.com/research/s3bqj2/photonic ) ... Photonic Integrated Circuit (Monolithic Integration, Hybrid Integration, Module ... to their offering. ... integration traces its roots in the latter half ... integration went unexplored and unfulfilled for several decades ...
(Date:7/10/2014)... Using microscopic polymer light resonators that expand in ... Quantum Photonics Laboratory have developed new optical sensors ... Optical sensors are ideal for detecting trace gas ... lightweight nature, and immunity to electromagnetic interference. , ... before, the MIT team conceived an extremely sensitive, ...
Breaking Biology Technology:Robert Harman, DVM Talks About What Stem Cells are in His Latest Blog Series for Vet-Stem, Inc. 2Robert Harman, DVM Talks About What Stem Cells are in His Latest Blog Series for Vet-Stem, Inc. 3Franciscan St. Anthony Health-Crown Point Underscores Patient Safety Commitment Through Expanded Use of Capnography 2International Photonic Integrated Circuit (Monolithic Integration, Hybrid Integration, Module Integration) Market - Forecasts to 2019 2Swell new sensors 2
... ISELIN, N.J., July 30 SyntheMed, Inc. (OTC ... development and commercialization of anti-adhesion products, announced today that ... its bioresorbable reverse thermal gelation polymer technology. This ... this novel technology and pertains to the application of ...
... , MONMOUTH JUNCTION, N.J., July ... into a cooperative research and development agreement with the National ... National Institutes of Health (NIH), to study ARIKACE(TM) (liposomal amikacin ... , , Transave and NIAID will collaborate ...
... , CHADDS FORD, Pa., July 30 Endo Pharmaceuticals ... quarter of 2009, including a full quarter of results of Indevus Pharmaceuticals, ... Total revenues during the second quarter of 2009 increased 22 percent ... 2008. Net income for the three months ended June 30, 2009, ...
Cached Biology Technology:SyntheMed Receives US Patent on Novel Polymer Technology 2Transave Enters Into Cooperative Research Agreement With NIH To Study ARIKACE(TM) In Nontuberculous Mycobacteria 2Transave Enters Into Cooperative Research Agreement With NIH To Study ARIKACE(TM) In Nontuberculous Mycobacteria 3Transave Enters Into Cooperative Research Agreement With NIH To Study ARIKACE(TM) In Nontuberculous Mycobacteria 4Endo Pharmaceuticals Reports Strong Second Quarter 2009 Financial Results 2Endo Pharmaceuticals Reports Strong Second Quarter 2009 Financial Results 3Endo Pharmaceuticals Reports Strong Second Quarter 2009 Financial Results 4Endo Pharmaceuticals Reports Strong Second Quarter 2009 Financial Results 5Endo Pharmaceuticals Reports Strong Second Quarter 2009 Financial Results 6Endo Pharmaceuticals Reports Strong Second Quarter 2009 Financial Results 7Endo Pharmaceuticals Reports Strong Second Quarter 2009 Financial Results 8Endo Pharmaceuticals Reports Strong Second Quarter 2009 Financial Results 9Endo Pharmaceuticals Reports Strong Second Quarter 2009 Financial Results 10Endo Pharmaceuticals Reports Strong Second Quarter 2009 Financial Results 11Endo Pharmaceuticals Reports Strong Second Quarter 2009 Financial Results 12Endo Pharmaceuticals Reports Strong Second Quarter 2009 Financial Results 13Endo Pharmaceuticals Reports Strong Second Quarter 2009 Financial Results 14Endo Pharmaceuticals Reports Strong Second Quarter 2009 Financial Results 15Endo Pharmaceuticals Reports Strong Second Quarter 2009 Financial Results 16
SHEEP ANTI BOVINE LACTOPEROXIDASE...
... in utility and flexibility press-to-seal silicone isolators ... of the researcher. They are available either ... sheet material that can be easily trimmed ... autoclavable and non-cytotoxic and can be used ...
Request Info...
... Provides up to 30 minutes of walkaway time. Automatic Calibration. Five minute cooldown ... port. ... ... ...
Biology Products: