Navigation Links
Genetic study of Neanderthal DNA reveals early split between humans and Neanderthals

f low-frequency derived alleles in Europeans where the derived allele matches Neanderthal. No site in the data set appears to be of this type."

However, Pritchard said, "We do not exclude the possibility of modest levels of genome admixture."

Pritchard's team suggests that human and Neanderthal shared a common ancestor about 706,000 years ago, and that the human and the Neanderthal ancestral populations split around 370,000 years ago. (Researchers found some genetic variation between the two species, which the team attributes to the ancestral population.) Both lines co-existed in Europe and western Asia until about 30,000 years ago.

The team used DNA extracted from a 38,000-year-old Neanderthal specimen from Vindija, Croatia. They recovered 65,250 base pairs of the Neanderthal's 3 billion total base pairs and utilized traditional sequencing technologies used for the Human Genome Project as well as the new parallel pyrosequencing method to clone and insert missing fragmented DNA and create a library of Neanderthal DNA.

Unlike the libraries used to sequence the human genome, which contained only human DNA fragments, the Neanderthal DNA library is riddled with contamination from microbes that lived off the nutrients in the Neanderthal remains, as well as contamination from humans handling the specimens.

However, the scientists performed a variety of studies to confirm that the vast majority of the human-like sequence in the library was indeed Neanderthal and not just contamination from human bone collectors and laboratory workers.

The researchers then verified the authenticity of the Neanderthal sequence by comparing it to the human and chimpanzee genomes. This revealed multiple locations where the Neanderthal sequence matched more closely to that of chimpanzee and not human. Using the comparison of the Neanderthal to the human and chimp genomes enabled the investigators to estimate the human-Neanderthal divergence
'"/>

Source:University of Chicago Medical Center


Page: 1 2 3

Related biology news :

1. Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down
2. Genetically modified natural killer immune cells attack, kill leukemia cells
3. Ants Genetic Engineering Leads To Species Interdependency
4. Genetic Variation Visualization - From EMBL
5. Genetically modified rice in China benefits farmers health, study finds
6. Infants With Rare Genetic Disease Saved by Cord Blood Stem Cells
7. Genetically Modified Natural Killer Immune Cells Attack, Kill Leukemia Cells
8. Genetic defects give the immune system the green light to attack the pancreas
9. Maine Researchers Find Exceptions to Old Rules of Genetic Inheritance
10. Genetic therapy reverses nervous system damage in animal model of inherited human disease
11. Infants with Rare Genetic Disease Saved By Cord Blood Stem Cells
Post Your Comments:
(Date:5/18/2015)... May 18, 2015 Fingerprint Cards (FPC) ... FPC1025, FPC1145, FPC1155 and FPC1035 from one if its module ... and including Q3 2015 and the sensors will be used ... order values for 2015 hereby amount to 740 MSEK to ... of 140 MSEK and a number of smaller orders not ...
(Date:5/11/2015)... 11, 2015 Curemark LLC, a privately held ... a new Phase III double blind, randomized, placebo-controlled clinical ... CM-AT, on all children ages 3-8 with Autism. Previously, ... III double blinded clinical trial for CM-AT in children ... the digestive enzyme chymotrypsin. This new trial will help ...
(Date:5/5/2015)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or the "Company"), ... market, reminds investors and media that  Mr. David Tunnell ... SECURE CONNEXIONS AMERICA 2015, held in Washington DC ... conference is organized into a series of nine session tracks. ... Fraud: Where is the Trust in Cyberspace? and will ...
Breaking Biology News(10 mins):Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 230 Million and Raises Revenue Guidance for 2015 2Curemark, LLC, Launches New Phase III Trial in Expanded Population of Children with Autism 2NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 2NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 3
... September 5, 2013, Shenzhen, China BGI in collaboration ... other Chinese institutes, have completed the genome sequencing of ... infectious disease tuberculosis (TB). The study published online in ... researchers to better understand the genetic basis underlying drug ...
... industry and cities, coupled with a rising world shortage of ... increase in the use of treated wastewater for farming and ... -- comparable in North America alone to the volume of ... in many nations, not even quantified. Of ...
... Mexico, Rocky Mountain juniper ( Juniperus scopulorum Sarg .) ... The juniper,s woodhighly valued for its durability, rich color, ... furniture, and fence posts. For centuries, the leaves and ... essential oil, have been used extensively by native people ...
Cached Biology News:Drug resistance-associated genes: A cornerstone for the control and protection against tuberculosis 2UN: Rising reuse of wastewater in forecast but world lacks data on 'massive potential resource' 2UN: Rising reuse of wastewater in forecast but world lacks data on 'massive potential resource' 3UN: Rising reuse of wastewater in forecast but world lacks data on 'massive potential resource' 4UN: Rising reuse of wastewater in forecast but world lacks data on 'massive potential resource' 5UN: Rising reuse of wastewater in forecast but world lacks data on 'massive potential resource' 6UN: Rising reuse of wastewater in forecast but world lacks data on 'massive potential resource' 7UN: Rising reuse of wastewater in forecast but world lacks data on 'massive potential resource' 8UN: Rising reuse of wastewater in forecast but world lacks data on 'massive potential resource' 9
(Date:5/21/2015)... (PRWEB) May 21, 2015 Veolia’s ... an exclusive North American distribution agreement with VWR ... system. , With more than 160 years of ... and services for laboratory and production facilities, has ... excellence and differentiated services to enable science. ...
(Date:5/20/2015)... (PRWEB) May 20, 2015 This year ... especially for lawns. US Patented Pearl’s Premium Ultra ... lawns around the country that are coming out of ... addresses a number of major global concerns related to ... “non-grass” grass – the alternative to the standard, water-wasting, ...
(Date:5/20/2015)... 2015  Health eCareers, the healthcare industry,s online ... job seekers looking for the flexibility of short-term ... and online tool dedicated exclusively to temporary and ... SHIFT enables employers to quickly find and hire ... diem and other temporary positions, eliminating the time ...
(Date:5/20/2015)... SAN DIEGO , May 20, 2015 /PRNewswire/ ... today announced a collaboration with Celgene Corporation to ... novel genomic biomarkers that associate with patient response ... collaboration is intended to help accelerate patient access ... increasing efficiencies in clinical research and development and ...
Breaking Biology Technology:Veolia’s TECTA™ B16 Instrument for E. Coli Detection is Offered Exclusively Through VWR 2Breakthrough 4th Generation Low Maintenance Lawn Seed Offers Solution to California Drought 2Health eCareers Launches SHIFT Mobile and Online Tool to Match Healthcare Employers with Temporary Job Seekers 2Health eCareers Launches SHIFT Mobile and Online Tool to Match Healthcare Employers with Temporary Job Seekers 3Cypher Genomics Collaborates with Celgene Corporation to Identify Novel Genomic Biomarkers 2
... and long-term disease-free survival of breast cancer patients; ... April 23 Clarient, Inc. ... anatomic pathology and molecular testing services resource for ... that it has been granted an exclusive intellectual ...
... , - Strong 10.3% Growth ... the world leader in ophthalmic optics, today,announced consolidated revenue of ... a reported 10.3% increase on the first quarter,of 2008. Excluding ... Despite contracting demand early in the ...
... today the opening,ceremony of its new active pharmaceutical ingredient ... to take over the site that,had been manufacturing Lipitor(R) ... April 6th and the transaction closed on the 8th; ... of manufacture for Pfizer but,will mostly make use of ...
Cached Biology Technology:Clarient Granted Exclusive License to Commercialize Breast Cancer Biomarker by Indiana University Research and Technology Corporation 2Clarient Granted Exclusive License to Commercialize Breast Cancer Biomarker by Indiana University Research and Technology Corporation 3Clarient Granted Exclusive License to Commercialize Breast Cancer Biomarker by Indiana University Research and Technology Corporation 4Clarient Granted Exclusive License to Commercialize Breast Cancer Biomarker by Indiana University Research and Technology Corporation 5Essilor : 2009 First Quarter Report 2Essilor : 2009 First Quarter Report 3Essilor : 2009 First Quarter Report 4Hovione Opens its New API Plant in Cork 2Hovione Opens its New API Plant in Cork 3
... of Flight Mass Analyzer for superior sensitivity, mass accuracy, and resolving ... m/z, * Precursor ion selection range: 150 - 4000 m/z, * ... with internal reference, * Dynamic range: 4 orders of magnitude ... ...
Four siRNAs targeting your gene of interest, providing gene silencing with 100% satisfaction guaranteed High knockdown potency , High specificity for minimal off-target effects , Flexible siR...
Mouse polyclonal antibody to BTAF1 - BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (Mot1 homolog, S. cerevisiae)...
... combines Harvard Apparatuss best pump mechanism, a well ... of configuration options. A lookup table in the ... all the major manufacturers. A bright, two line ... from across the lab. All models have RS-232 ...
Biology Products: