Navigation Links
Genetic links could unlock clues to leading cause of blindness

Age-related macular degeneration is the leading cause of blindness in older adults, yet researchers are still in the dark about many of the factors that cause this incurable disease.

But new insight from University of Florida and German researchers bout a genetic link between rhesus monkeys with macular degeneration and humans could unlock secrets about the earliest stages of the disease, when severe vision loss could still be stopped.

The researchers pinpointed a chromosome region and genetic markers for macular degeneration in humans and rhesus monkeys, findings recently published in the online edition of the journal Experimental Eye Research. Linking the disease in monkeys to the disease in humans allows researchers to study how it progresses in the animals, which could lead to better treatments and even a cure.

"Stopping the development of the disease is something the monkeys will help us do that we can't do with humans," said William W. Dawson, a UF professor of ophthalmology and physiology and a co-author of the study. "This is a big step forward in dealing with the disease."

The researchers studied seven genetic sites in the monkeys that correspond to human chromosomes linked to macular disease. One of those areas, the findings confirm, contains genes that predict age-related macular degeneration in humans and rhesus monkeys. Dawson and other researchers have suspected for years that the disease was very similar in humans and monkeys, but these findings finally establish that. This discovery, he said, will allow researchers to delve deeper into what causes the disease and could be the first step toward repairing the genetic defects linked to it.

According to the National Eye Institute, nearly 2 million Americans have advanced age-related macular degeneration, a disease that develops when a small, light-detecting part of the retina called the macula breaks down. Seven million more Americans have an intermediate form of th
'"/>

Source:University of Florida


Page: 1 2 3

Related biology news :

1. Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down
2. Genetically modified natural killer immune cells attack, kill leukemia cells
3. Ants Genetic Engineering Leads To Species Interdependency
4. Genetic Variation Visualization - From EMBL
5. Genetically modified rice in China benefits farmers health, study finds
6. Infants With Rare Genetic Disease Saved by Cord Blood Stem Cells
7. Genetically Modified Natural Killer Immune Cells Attack, Kill Leukemia Cells
8. Genetic defects give the immune system the green light to attack the pancreas
9. Maine Researchers Find Exceptions to Old Rules of Genetic Inheritance
10. Genetic therapy reverses nervous system damage in animal model of inherited human disease
11. Infants with Rare Genetic Disease Saved By Cord Blood Stem Cells
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Genetic links could unlock clues leading cause blindness

(Date:8/27/2014)... 27, 2014 University of Utah biologist agan Sekercioglu, ... has won that nation,s highest science prize, which is ... Sekercioglu is among five researchers picked for 2014 the ... Council of Turkey. Three researchers won the Science Award ... Award, which is equivalent to the Science Award but ...
(Date:8/27/2014)... greatest risk to Europe based upon a proxy for ... using a ,big data, approach to scientific research. , ... Global Health ranked the top 100 pathogens affecting humans ... system which, they believe, will help governments across the ... infectious diseases, including as a result of climate change, ...
(Date:8/27/2014)... 2014 /PRNewswire-iReach/ -- The IEEE Engineering in Medicine and ... Annual International Conference (EMBC,14), this year being held at ... Chicago, Illinois , from Tuesday, August 26 through ... and industry professionals in science, medicine, and engineering are ... This year,s conference theme is ...
Breaking Biology News(10 mins):University of Utah biologist wins Turkey's top science prize 2Big data approach identifies Europe's most dangerous human and domestic animal pathogens 2Global Leaders In Science, Medicine, And Engineering Gather For The 36th Annual International Conference Of The IEEE Engineering In Medicine And Biology Society, August 26-30 In Chicago 2Global Leaders In Science, Medicine, And Engineering Gather For The 36th Annual International Conference Of The IEEE Engineering In Medicine And Biology Society, August 26-30 In Chicago 3
... remarkable eyes of a marine crustacean could inspire the next ... study from the University of Bristol published today in ... are found on the Great Barrier Reef in Australia and ... They can see in twelve colours (humans see in only ...
... 23 GenVault Corporation, the leader in ambient temperature ... announced that David Wellis, Ph.D., GenVault,s President and CEO, ... place on October 26th and 27th in La Jolla, ... an overview of the company together with recent customer, ...
... A bioethicist who specializes in moral dilemmas families face ... the first-ever March of Dimes Distinguished Lectureship in Perinatal Bioethics. ... John D. Lantos, MD, a nationally-recognized pediatrician and ethicist, delivered ... at the American Society of Bioethics and Humanities, 11th annual ...
Cached Biology News:Mantis shrimps could show us the way to a better DVD 2GenVault Corporation to Present at the 2009 BIOCOM Investor Conference 2March of Dimes establishes 2 new perinatal bioethics awards 2
(Date:8/27/2014)... 2014 Research and Markets  has ... Acid  (Biodegradable Polymer, Food & Beverage, Personal Care ... 2019" report to their offering. ... an asymmetrical carbon atom. The main applications of ... and beverage, personal care product, and pharmaceutical industries. ...
(Date:8/27/2014)... , Aug. 27, 2014 Guggenheim Securities, ... Partners, today announced the hiring of veteran equity analyst ... equity analyst. Mr. Butler will focus on the biotech/biopharma ... team a wealth of experience and a broad network ... , Senior Managing Director and Head of Equities at ...
(Date:8/27/2014)... , Aug. 27, 2014 Research and ... Stable Isotope Ratio Mass Spectrometer Industry Report 2014" ... Stable Isotope Ratio Mass Spectrometer Industry Report 2014 is ... of the global isotope ratio mass spectrometer industry. ... industry including definitions, classifications, applications and industry chain structure. ...
(Date:8/27/2014)... BIOEQUA, an innovative line of skin care ... handheld spray, has made its EQUA ESSENTIAL line available ... brand began with an unexpected discovery in an emergency ... that the application of nanospray technology allowed for liquid ... to skin's basal layer. This resulted in immediate absorption ...
Breaking Biology Technology:Global Lactic Acid (Biodegradable Polymer, Food & Beverage, Personal Care & Pharmaceutical) Market - Trends & Forecasts to 2019 2Guggenheim Securities Hires Analyst Charles "Tony" Butler to Expand Healthcare Coverage 2Global Stable Isotope Ratio Mass Spectrometer Industry Report 2014 2BIOEQUA'S EQUA ESSENTIAL Product Line Redefines Skin Care & Now Available in America 2
... to Support Development of Renewable Replacement for Light ... ... 27 Solazyme, a,bioscience company pioneering biofuels and health/wellness products from,microalgae, ... Institute of Standards and Technology to develop a,biopetroleum derived from marine ...
... E. coli bacteria, Duke University chemists and engineers have ... imprinted to create microdevices such as labs-on-a-chip. , Their ... to 1 nanometer, or billionths of a meter, the ... of the Journal of Organic Chemistry. , "This ...
... LOUIS, Sept. 27 Sigma-Aldrich (Nasdaq:,SIAL) is pleased ... named the,Vice President of R&D for the Research ... role, he will help expand Sigma-Aldrich,s,leadership position through ... science researchers. Sullivan has been involved with Sigma-Aldrich,since ...
Cached Biology Technology:Solazyme Selected for National Institute of Standards and Technology Award 2Using catalysts to stamp nanopatterns without ink 2Using catalysts to stamp nanopatterns without ink 3Sigma-Aldrich Names Patrick Sullivan New VP of Research and Development for Research Biotech 2
Liquid. 50 μg/ml in PBS, pH 7.4. PROTECT FROM LIGHT. A convenient form of propidium iodide useful for flow cytometry studies. RTECS SF7949600, CAS 25535-16-4, M.W. 668.4. ...
... is used for conventional PCR and thermal ... personal thermal cycler, which features a 96-well ... tubes or plates, programmable time, temperature, and ... modes of temperature control. The system also ...
... been developed for affinity capture of ... of ProteinChip chemical surfaces allow differential ... unique biochemical properties. Each chip has ... comparison, and the chips are color-coded ...
The Freeze 'N Squeeze DNA gel extraction kit uses a quick freeze-and-thaw cycle and centrifugation to draw 50-23,000 bp DNA out of agarose gel slices. The kit includes materials for 100 preps....
Biology Products: