Navigation Links
Genetic links could unlock clues to leading cause of blindness

Age-related macular degeneration is the leading cause of blindness in older adults, yet researchers are still in the dark about many of the factors that cause this incurable disease.

But new insight from University of Florida and German researchers bout a genetic link between rhesus monkeys with macular degeneration and humans could unlock secrets about the earliest stages of the disease, when severe vision loss could still be stopped.

The researchers pinpointed a chromosome region and genetic markers for macular degeneration in humans and rhesus monkeys, findings recently published in the online edition of the journal Experimental Eye Research. Linking the disease in monkeys to the disease in humans allows researchers to study how it progresses in the animals, which could lead to better treatments and even a cure.

"Stopping the development of the disease is something the monkeys will help us do that we can't do with humans," said William W. Dawson, a UF professor of ophthalmology and physiology and a co-author of the study. "This is a big step forward in dealing with the disease."

The researchers studied seven genetic sites in the monkeys that correspond to human chromosomes linked to macular disease. One of those areas, the findings confirm, contains genes that predict age-related macular degeneration in humans and rhesus monkeys. Dawson and other researchers have suspected for years that the disease was very similar in humans and monkeys, but these findings finally establish that. This discovery, he said, will allow researchers to delve deeper into what causes the disease and could be the first step toward repairing the genetic defects linked to it.

According to the National Eye Institute, nearly 2 million Americans have advanced age-related macular degeneration, a disease that develops when a small, light-detecting part of the retina called the macula breaks down. Seven million more Americans have an intermediate form of th
'"/>

Source:University of Florida


Page: 1 2 3

Related biology news :

1. Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down
2. Genetically modified natural killer immune cells attack, kill leukemia cells
3. Ants Genetic Engineering Leads To Species Interdependency
4. Genetic Variation Visualization - From EMBL
5. Genetically modified rice in China benefits farmers health, study finds
6. Infants With Rare Genetic Disease Saved by Cord Blood Stem Cells
7. Genetically Modified Natural Killer Immune Cells Attack, Kill Leukemia Cells
8. Genetic defects give the immune system the green light to attack the pancreas
9. Maine Researchers Find Exceptions to Old Rules of Genetic Inheritance
10. Genetic therapy reverses nervous system damage in animal model of inherited human disease
11. Infants with Rare Genetic Disease Saved By Cord Blood Stem Cells
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Genetic links could unlock clues leading cause blindness

(Date:10/30/2014)... therapeutics present unique challenges when it comes to ... harm. New consensus guidelines for toxicity testing that ... characteristics of these novel biopharmaceuticals are presented in ... from Mary Ann Liebert, Inc. publishers . ... Nucleic Acid Therapeutics website until November 30, ...
(Date:10/29/2014)... oil and gas production are well over recommended levels ... access journal Environmental Health . High levels of ... is the first to be based on community sampling ... be used to supplement official air-quality monitoring programs. , ... not readily flow to the surface. This is because ...
(Date:10/29/2014)... genetic and environmental, have been blamed for increasing ... such as a family history of schizophrenia, are ... Toxoplasma gondii , a parasite transmitted by soil, ... with skepticism. , A new study by Gary ... the University of Pennsylvania,s School of Veterinary Medicine, ...
Breaking Biology News(10 mins):New guidelines for reproductive & developmental toxicity testing of oligonucleotide drugs 2Air quality and unconventional oil and gas sites 2Air quality and unconventional oil and gas sites 3Penn vet professor investigates parasite-schizophrenia connection 2Penn vet professor investigates parasite-schizophrenia connection 3
... Lugano-CH, Brussels-BE, 2 May 2013 -- Breast cancers contain ... expression, but a new study provides reassurance that this ... expression tests to help tailor cancer treatments to individual ... IMPAKT Breast Cancer Conference in Brussels, Belgium. The IMPAKT ...
... (Boston) A Boston University School of Medicine (BUSM) ... helps increase their self-compassion and ability to manage thoughts ... Medical Education Online , also discusses how this innovative ... feel more empowered to use mind-body skills with their ...
... Francisco, CA PLOS, the Public Library of Science, ... that recognizes the use of scientific research, published through ... field that benefit society. Major sponsors include the Wellcome ... who have used, applied or remixed scientific research to ...
Cached Biology News:Breast cancer heterogeneity no barrier to predictive testing, study shows 2BUSM study shows positive impact of mind-body course on well-being of medical students 2PLOS announces Accelerating Science Award Program 2
(Date:10/30/2014)... Global polyvinyl chloride (PVC) demand registered a significant ... especially in North America and Europe. However, the global ... a growing trend. , The largest chunk of the ... segment. In 2013, the key PVC application spheres included ... film. Moreover, the PVC was consumed in the production ...
(Date:10/30/2014)... San Diego, CA (PRWEB) October 30, 2014 ... company announced today that they have manually curated public ... Pharma and non profit customers. the data is ... BioSciences manually curates and unifies public and internal data ... more value and knowledge out of the data that ...
(Date:10/30/2014)... Avure Technologies celebrates a year of success and the ... fleet of high volume High Pressure Processing (HPP) systems. , ... to PackExpo this year, which is where we first announced ... Williams, CEO at Avure. “Sales of the new Avure machine ... the challenges of market demand for higher throughput. We sold ...
(Date:10/30/2014)... 30, 2014  Regado Biosciences, Inc. (Nasdaq: ... conference call and live audio webcast on Thursday, November ... third quarter 2014 financial results. Interested participants ... (888) 347-1165 for domestic callers or (412) 902-4276 for ... under the investor relations section of the Regado website ...
Breaking Biology Technology:Global Polyvinyl Chloride Demand Is on Upward Trend Now, Says Merchant Research & Consulting in Its Topical Study 2Global Polyvinyl Chloride Demand Is on Upward Trend Now, Says Merchant Research & Consulting in Its Topical Study 3Rancho BioSciences Manually Curated TCGA Data Sets Available 2In High Demand: New High Pressure Processing (HPP) System with Maximum Throughput Drives Strong Sales 2In High Demand: New High Pressure Processing (HPP) System with Maximum Throughput Drives Strong Sales 3Regado Biosciences to Provide Third Quarter 2014 Financial Results 2
... Reportlinker.com announces that a new market research report ... Technology Roadmap http://www.reportlinker.com/p0312814/ Photovoltaic-Technology-Roadmap.html ... a low-cost source of clean and renewable energy is ... of them have agreed on a 20% renewable energy ...
... maker of the patented probiotic strain GanedenBC30® , recently ... the use and scope of the Ganeden BC30 ® ... improve digestive and immune health.   The 100th ... Organic Milling marking a milestone for the company ...
... IOWA (14 October 2010)Crop specialists in Kenya and Uganda ... commence later this year for new varieties of maize ... 300 million Africans for whom maize is life, according ... the African Agricultural Technology Foundation (AATF) at the World ...
Cached Biology Technology:Reportlinker Adds Photovoltaic Technology Roadmap 2Reportlinker Adds Photovoltaic Technology Roadmap 3Reportlinker Adds Photovoltaic Technology Roadmap 4Ganeden Biotech Granted 100th Probiotic Patent 2Scientists prepare for confined field trials of life-saving drought-tolerant transgenic maize 2Scientists prepare for confined field trials of life-saving drought-tolerant transgenic maize 3
Polaroid black & white positive, 3 x 4 inch pack film, ISO 3000/ 36 ASA DIN (20 expsures). For use in the Polaroid Direct Copy Camera (PHC34)....
Applications: (+) Immunocytochemistry and immunohistochemistry...
For the quantitative determination of canine Interferon gamma,(IFN-γ) concentrations in cell culture supernates, serum and,plasma....
Non-Protein Peroxidase Stabilizer , 1 L...
Biology Products: