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Gene therapy research switches off joint inflammation; switches on genetic process of joint repair

Scientists at Case Western Reserve University School of Medicine and Albany Medical College, together with Rainforest Nutritionals, Inc. have demonstrated in a mini symposium held today at the 14th International Conference of the Inflammation Research Association (IRA) that a blend of natural botanical products called Reparagen have turned on the master repair gene, IGF-1, which is responsible for growing human cartilage and restores joint function while blocking joint destruction associated with inflammation. The IRA is the preeminent meeting for inflammation investigators.

Mark J.S. Miller, Ph.D., M.B.A., Professor of Cardiovascular Sciences and Pediatrics at Albany Medical College (NY) and head of the Reparagen’s Scientific Advisory Board said that, "Sixty six million people have poor joint health; 20 million people suffer from osteoarthritis. Compromised joint health is a major contributor to comprised quality of life. No product of any kind has been able to demonstrate this combination of actions. These findings have been published in peer-review journals and presented to learned societies. The commercialization of Reparagen has been supported by the US government with a grant from the National Institutes of Health.

"Glucosamine is currently a gold standard in the natural product approach to joint health with $1 billion in annual sales but recent studies have questioned its effectiveness. There are no therapies on the market today that work by activating the genes that control the process of joint repair. Reparagen’s approach is unique, in that it switches ‘off?the genes that control joint destruction and inflammation while turning ‘on?the process of inserting glucosamine into new cartilage. Without this activated repair process glucosamine cannot be effective.1 So this solves a riddle that has plagued researchers for decades and corrects a problem that is exacerbated with aging.

Multi-center, Randomized controlled Clinical Trial
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Source:nedelman@version.net


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