Navigation Links
Gene therapy injected into the brains' of mice with Huntington's disease

Researchers at Rush University Medical Center, Chicago, and Ceregene Inc., San Diego, have successfully used gene therapy to preserve motor function and stop the anatomic, cellular changes that occur in the brains of mice with Huntington's disease (HD). This is the first study to demonstrate that, using this delivery method, symptom onset might be prevented in HD mice with this treatment.

Results of the study were published in the Proceedings of the National Academy of Sciences of the United States, June 13, 2006.

"This could be an important step toward a disease modifying therapy," says co-author Jeffrey H. Kordower, PhD, director of the Research Center for Brain Repair at Rush. "We could potentially be stopping the disease process in its tracks, delaying symptoms from ever showing up."

Huntington's disease is an inherited degenerative disease that progressively robs patients of the ability to think, judge appropriately, control their emotions and perform coordinated tasks. HD typically begins in mid-life, between the ages of 40 and 50. There is no effective treatment or cure for this fatal illness that affects 30,000 Americans and places another 75,000 at risk.

Kordower says this research, if eventually applied to humans, could help those who have HD or, due to the presence of a genetic test, are known to be destined to get HD.

"Each child of an affected parent has a 50 percent risk for inheriting the disease. Genetic testing can identify mutated gene carriers destined to suffer from HD. Unlike other neurodegenerative disorders, identification of the genetic markers provides a unique opportunity to intercede therapeutically before or extremely early in the disease process–only a small fraction of potential carriers get tested. But, if there was a treatment, especially one that altered the natural course of disease, potentially halting it, we would hope every potential patient would get tested so they could avail themselves
'"/>

Source:Rush University Medical Center


Page: 1 2 3 4

Related biology news :

1. Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer
2. Columbia research lifts major hurdle to gene therapy for cancer
3. Combination therapy boosts effectiveness of telomere-directed cancer cell death
4. Gene therapy converts dead bone graft to new, living tissue
5. Study identifies predictors of HIV drug resistance in patients beginning triple therapy
6. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
7. Muscle-targeted gene therapy reverses rare muscular dystrophy in mice
8. New therapy for HIV/AIDS eliminates needles and excessive toxicity
9. New Treatment Rivals Chemotherapy For Lymphoma, Study Finds
10. Gene therapy for Parkinsons disease moves forward in animals
11. Pulsating ultrasound enhances gene therapy for tumors
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Gene therapy injected into the brains mice with Huntington disease

(Date:6/9/2015)... 2015 Research and Markets  ( http://www.researchandmarkets.com/research/xsgs2s/gesture ... "Gesture Recognition & Touchless Sensing Market by Technology ... Others), Product (Biometric & Sanitary Equipment) & by ... to their offering. The total gesture ... reach $ 23.55 Billion by 2020 at a ...
(Date:6/8/2015)... WASHINGTON , June 8, 2015  The ... announced today their selection of Troy Potter ... Chairman, effective immediately. SIBA is a non-profit association ... promote responsible policy, education and implementation of solutions ... public platforms. ...
(Date:6/4/2015)... , June 4, 2015  Today, the co-chairs of the ... involving U.S. high-level biocontainment labs and USA ... co-chairs expressed grave concerns over the findings of lax safety ... nation,s lab biosecurity. ... is extremely troubling," said Joe Lieberman , former senator ...
Breaking Biology News(10 mins):Global Gesture Recognition & Touchless Sensing (Technology, Application & Products) Market 2015-2020 2Secure Identity & Biometrics Association (SIBA) Names Troy Potter of L-3 National Security Solutions as Chairman 2Secure Identity & Biometrics Association (SIBA) Names Troy Potter of L-3 National Security Solutions as Chairman 3Secure Identity & Biometrics Association (SIBA) Names Troy Potter of L-3 National Security Solutions as Chairman 4Secure Identity & Biometrics Association (SIBA) Names Troy Potter of L-3 National Security Solutions as Chairman 5Biodefense Panel Expresses Grave Concerns over Findings at Nation's Research Labs 2Biodefense Panel Expresses Grave Concerns over Findings at Nation's Research Labs 3
... September 12, 2011A study presented today by Universit Laval researchers ... in Quebec City revealed that the risk of insomnia is ... one member is an insomniac. The research team, ... of Psychology, came to these conclusions following a study involving ...
... liquids has been intimately entwined since Lon Foucault discovered the ... travels more slowly in water than in air. This physical ... collect and drive light to where it can be the ... on optofluidics, the study of microfluidicsthe microscopic delivery of fluids ...
... induced pluripotent stem cells were first derived in 2007, scientists ... cells, which are sourced in early-stage embryos. Both cell ... the body, but their origins in embryonic and adult ... both cell types have great potential in basic biological research ...
Cached Biology News:A guiding light for new directions in energy production 2A guiding light for new directions in energy production 3Study reveals critical similarity between two types of do-it-all stem cells 2Study reveals critical similarity between two types of do-it-all stem cells 3
(Date:6/29/2015)... ... June 30, 2015 , ... This cutting edge standard making is ... Featuring 12 distinct peaks, the WAV-8 is the world’s first cuvette-shaped, solid-state filter that ... into the NIR range. Previous spectrophotometer calibration standards, such as those made from didymium ...
(Date:6/29/2015)... , ... June 29, 2015 , ... ... CAGR of around 19% during the forecast period (2015 to 2020). The market ... upsurge in government and corporate funding for R&D. However, lack of adequate healthcare ...
(Date:6/29/2015)... -- MiMedx Group, Inc. (NASDAQ: MDXG ), the leading ... processes to develop and market advanced products and therapies ... Ophthalmic and Dental sectors of healthcare, announced that its ... awarded the Lifetime Achievement Award in the EY Entrepreneur ... The Entrepreneur Of The Year Program, now in its ...
(Date:6/29/2015)... ... ... The StampedeCon 2015 Big Data Conference will be taking place ... will bring top technology professionals to St. Louis. Top industry speakers will share their ... The event is proudly sponsored by DataStax, Cisco, World Wide Technology, Hortonworks, OCI, HP, ...
Breaking Biology Technology:FireflySci Releases Spectrophotometer Calibration Standards for NIR Wavelength Accuracy Verification 2FireflySci Releases Spectrophotometer Calibration Standards for NIR Wavelength Accuracy Verification 3Microfluidics Market Growing at 19.3% CAGR To 2020 – New research available at ReportsnReports.com 2Microfluidics Market Growing at 19.3% CAGR To 2020 – New research available at ReportsnReports.com 3Microfluidics Market Growing at 19.3% CAGR To 2020 – New research available at ReportsnReports.com 4Microfluidics Market Growing at 19.3% CAGR To 2020 – New research available at ReportsnReports.com 5EY Entrepreneur Of The Year Program Recognizes Pete Petit, The Chairman & CEO of MiMedx 2StampedeCon Announces 2015 Agenda 2StampedeCon Announces 2015 Agenda 3
... Transition to ... Market, SUNNYVALE, Calif., Feb. 28 Cepheid (Nasdaq:,CPHD) today announced financial results for the ... year 2007:, -- Total revenues of $129.5 million, a 48 percent increase from ... - Total product sales of $116.5 million, a 41 percent increase ...
... the Kansas,Bioscience Authority, Kansas State University is gearing ... will keep research laboratories,safe and secure -- so ... research to combat infectious diseases., Bioscience research ... to unprecedented demand for biosafety and biocontainment,training, according ...
... Feb. 28 A free white paper ... environmental health and,safety (EH&S) compliance programs is ... "Small and midsized companies and institutions ... safety compliance programs,involving federal, state, and local ...
Cached Biology Technology:Cepheid Reports Fourth Quarter and Full Year 2007 Results 2Cepheid Reports Fourth Quarter and Full Year 2007 Results 3Cepheid Reports Fourth Quarter and Full Year 2007 Results 4Cepheid Reports Fourth Quarter and Full Year 2007 Results 5Cepheid Reports Fourth Quarter and Full Year 2007 Results 6Cepheid Reports Fourth Quarter and Full Year 2007 Results 7Cepheid Reports Fourth Quarter and Full Year 2007 Results 8Cepheid Reports Fourth Quarter and Full Year 2007 Results 9Cepheid Reports Fourth Quarter and Full Year 2007 Results 10Cepheid Reports Fourth Quarter and Full Year 2007 Results 11Cepheid Reports Fourth Quarter and Full Year 2007 Results 12Cepheid Reports Fourth Quarter and Full Year 2007 Results 13Cepheid Reports Fourth Quarter and Full Year 2007 Results 14K-State Preparing to Share Expertise With Bioscientists 2White Paper Details Environmental Health & Safety Compliance Strategies for Laboratories 2
HybriWell™ hybridization sealing system, 20 mm diameter chamber, 0.15 mm deep *set of 100*...
Recombinant Equine TNF-alpha/TNFSF1A, CF...
GRADIENT MAKER, 30 ML, 1 EA. Category: Protein Vertical Instruments....
DALT GRADIENT MAKER,230V, 1 EA. Category: 2D DALT Systems....
Biology Products: