Navigation Links
Gene therapy for Parkinson's disease moves forward in animals

brain to replenish its dwindling supply of dopamine, sidetracking the destructive course of Parkinson's disease. But eventually the treatment can backfire.

"Levodopa generally works great for several years, but then it actually starts creating movement problems," Mandel said. "Our idea is that instead of taking pills that create detrimental fluctuations of L-dopa levels, a continuous, therapeutic dose would be better for you.

As for efforts to reverse impaired movements in rats, scientists used 33 animals with severe dopamine depletion and transferred a gene to provide a source of L-dopa production into the animals' striata. Before receiving the treatment, all animals had limited use in their left paws. After treatment, the animals receiving the therapeutic enzyme mixture show complete recovery in their paws. Researchers say not only did the rats recover substantial degrees of function in their impaired forelimbs, continuous levels of L-dopa were being produced in their brains, blocking side effects.


'"/>

Source:University of Florida


Page: 1 2 3 4

Related biology news :

1. Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer
2. Columbia research lifts major hurdle to gene therapy for cancer
3. Combination therapy boosts effectiveness of telomere-directed cancer cell death
4. Gene therapy converts dead bone graft to new, living tissue
5. Study identifies predictors of HIV drug resistance in patients beginning triple therapy
6. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
7. Muscle-targeted gene therapy reverses rare muscular dystrophy in mice
8. New therapy for HIV/AIDS eliminates needles and excessive toxicity
9. New Treatment Rivals Chemotherapy For Lymphoma, Study Finds
10. Pulsating ultrasound enhances gene therapy for tumors
11. Antiretroviral therapy may prevent excess risk of some cancers in people with HIV
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Gene therapy for Parkinson disease moves forward animals

(Date:12/17/2014)... Dec. 16, 2014 Valencell, a leader in performance ... technology to industry leaders such as Intel, Jabra, Atlas, ... biometric wearable products. These products will be showcased at ... Las Vegas . "Our partners ...
(Date:12/11/2014)... , Dec. 09, 2014 Research and Markets ... ( http://www.researchandmarkets.com/research/twhjll/biometrics_market ) has announced the addition of the ... to their offering. One major trend ... continuous advances in technology, it is important to upgrade ...
(Date:12/10/2014)... YORK , Dec. 8, 2014 You,ve been here before: ... can,t remember your password, site key or the answer to your ... teacher? Today, Hoyos Labs , a digital ... put an end to the frustration that comes with usernames, passwords ...
Breaking Biology News(10 mins):Valencell PerformTek Biometrics Power the Most Accurate Wearables at CES 2015 2Biometrics Market in the APAC Region 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3
... existed in the Amazon before the arrival of Europeans, ... the result of research led by Crystal McMichael and ... The finding overturns the idea the Amazon was a ... that transformed vast tracts of the landscape. The ...
... vegetarian and ecological products, but is it really making ... about ethical trade, Gothenburg researchers Bengt Brlde and ... help ease people,s bad conscience, it does nothing to ... fixing the problem will require collective solutions, such as ...
... UC Santa Barbara scientists turned to the simple sponge to ... and found that, but for a mechanism that coordinates the ... synapses, sponges and the rest of the animal world may ... of a protosynaptic gene expression network," are published in the ...
Cached Biology News:Scientists reconstruct pre-Columbian human effects on the Amazon Basin 2Ethical trade: 'Good intentions go to waste' 2Clues to nervous system evolution found in nerve-less sponge 2
(Date:1/22/2015)... MA (PRWEB) January 22, 2015 zFlo ... is pleased to announce an exciting product from a new ... motion analysis solutions over the past 15 years, with offerings ... Most recently, their 3D IMU system (inertial measurement unit), iSen, ...
(Date:1/22/2015)... 2015 Selexis SA, a serial innovation ... Banks (RCBs) used for drug discovery to commercial manufacturing, ... include Next-Generation Sequencing (NGS) data packages. The ... manufacturing by ensuring the integrity of the gene, validation ...
(Date:1/22/2015)... Jan. 22, 2015   Cypher Genomics, Inc., ... (NASDAQ: SQNM ), the leading molecular ... next generation noninvasive prenatal tests (NIPT). Through this ... called Mantis™, to advance analysis of clinically-relevant fetal ...
(Date:1/22/2015)...  Derma Sciences, Inc. (Nasdaq: DSCI ), ... care, announces that AMNIOEXCEL® and AMNIOMATRIX®, amniotic allografts ... the Premier, Inc. Regenerative Skin Grafting contract portfolio. ... and AMNIOMATRIX® product lines, which continue to be ...
Breaking Biology Technology:3D Motion Capture Just Got Easy 2Selexis Generated Research Cell Banks Now Fully Sequenced Using Next-Generation Sequencing 2Cypher Genomics and Sequenom Announce Development Agreement 2Cypher Genomics and Sequenom Announce Development Agreement 3Cypher Genomics and Sequenom Announce Development Agreement 4Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 2Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 3Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 4Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 5
... LIVERPOOL, February 2 Gray Healthcare has ... to lead its,expanding Community Recovery Team, as Clinical Director. ... years, experience of senior management in mental,health in both the ... of operations at Cambian Healthcare, covering 12 psychiatric,rehabilitation hospitals, he ...
... SAN DIEGO , Feb. 1 BioMed Realty Trust, Inc. ... its fourth quarter and year ended December 31, 2009 after ... Alan D. Gold , Chairman and Chief Executive Officer, and ... conference call at 10:00 a.m. Pacific Time on Thursday, ...
... Astrogenetix ... Space Station (ISS) to 2020 or beyond. , ... (Vocus) February 1, 2010 -- Astrogenetix is issuing the following statement applauding ... beyond. , ,Thomas B. Pickens III, Chairman of Astrogenetix, Inc.:, , ,“We are excited to ...
Cached Biology Technology:Noel Tracey to Head Up Gray Healthcare Recovery Team 2BioMed Realty Trust to Report 2009 Fourth Quarter and Year-End Results 2Astrogenetix Statement On Nasa's Fiscal Year 2011 Budget Announcement 2
... Polyclonal Phosphorylated Anti-GluR1 Glutamate is the ... many years it had been considered to ... NMDA, AMPA and kainate receptors that are ... Recently, glutamate has been shown to regulate ...
Anti-ADP-Ribosylation Factor 1, clone 3F1 Immunogen: Synthetic peptide corresponding to the C-terminal amino acid sequence of human ARF1. Available Date: 38495...
TNF-Related Apoptosis Inducing Ligand-Receptor-1...
Pim-1 (12H8)...
Biology Products: