Navigation Links
Gene study shows three distinct groups of chimpanzees

The largest study to date of genetic variation among chimpanzees has found that the traditional, geography-based sorting of chimps into three populations—western, central and eastern—is underpinned by significant genetic differences, two to three times greater than the variation between the most different human populations.

In the April 2007 issue of the journal PLOS Genetics, researchers from the University of Chicago, Harvard, the Broad Institute and Arizona State show that there has been very little detectable admixture between the different populations and that chimps from the central and eastern populations are more closely related to each other than they are to the western "subspecies."

They also devised a simplified set of about 30 DNA markers that zookeepers or primatologists could use to determine the origins of a chimpanzee with uncertain heritage.

"Finding such a marked difference between the three groups has important implications for conservation," said Molly Przeworski, PhD, assistant professor of human genetics at the University of Chicago and a senior author of the study. "It means we have to protect three separate habitats, all threatened, instead of just one."

To unravel the evolutionary history to chimpanzees, the research team collected DNA from 78 common chimpanzees and six bonobos, a separate species of chimpanzee, and examined 310 DNA markers from each.

They found four "discontinuous populations," three of common chimps plus the bonobos. Hybrids, those with at least five percent of their DNA from more than one common chimpanzee population were rare, with most of the hybrid chimps born in captivity.

"We saw little evidence of migration between groups in the wild," said Celine Becquet, first author of the paper and a graduate student in Przeworski's laboratory. "Part of that could stem from the gaps in our samples, but we think most of this separation is genuine, a long-term consequenc e of geographic isolation."

The original boundaries between groups may have been the emergence and growth of rivers, such as the Congo River, which is thought to be about 1.5 million years old. "Chimps don't swim," Becquet said. "For them, water provides a very effective border." The ongoing loss of habitat has increased the physical separation between the three groups.

The extent of accumulated genetic difference enabled the researchers to speculate about when the different populations separated. They estimate that bonobos, which live south of the Congo River, split off from the ancestors of modern chimpanzees about 800,000 years ago. Western chimps appear to have separated from central and eastern chimpanzees about 500,000 years ago and central and eastern chimps divided about 250,000 years ago.

"Even though the chimp genome has been sequenced, it's amazing how little we know about their evolution and the level of variation within chimpanzees," said Przeworski. "These are our nearest relatives, closer to humans than they are to gorillas, yet we know so little about them, and even less about gorillas and orangutans."

The chimpanzee genome differs from the bonobo genome by about 0.3 percent, which is one-fourth the distance between humans and chimps. Yet chimps and bonobos have radically different social systems, cultures, diets and mating systems.

On the other hand, in this study, looking at three "subspecies" of common chimpanzees, "we found significant genetic variation," said Przeworski, "but there's very little detectable difference between the populations in terms of appearance or behavior."


'"/>

Source:University of Chicago Medical Center


Related biology news :

1. Bioartificial kidney under study at MCG
2. W.M. Keck Foundation funds study of friendly microbes
3. Yellowstone microbes fueled by hydrogen, according to U. of Colorado study
4. Genome-wide mouse study yields link to human leukemia
5. Clam embryo study shows pollutant mixture adversely affects nerve cell development
6. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
7. Same mutation aided evolution in many fish species, Stanford study finds
8. Sequencing of marine bacterium will help study of cell communication
9. Genetically modified rice in China benefits farmers health, study finds
10. A new study examines how shared pathogens affect host populations
11. NYU study reveals how brains immune system fights viral encephalitis
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/11/2017)... , April 11, 2017 Crossmatch®, ... secure authentication solutions, today announced that it has ... Advanced Research Projects Activity (IARPA) to develop next-generation ... program. "Innovation has been a driving ... Thor program will allow us to innovate and ...
(Date:4/5/2017)... , April 5, 2017  The Allen Institute for ... Cell Explorer: a one-of-a-kind portal and dynamic digital window ... imaging data, the first application of deep learning to ... stem cell lines and a growing suite of powerful ... for these and future publicly available resources created and ...
(Date:3/30/2017)... 30, 2017  On April 6-7, 2017, Sequencing.com will ... hackathon at Microsoft,s headquarters in ... focus on developing health and wellness apps that provide ... the Genome is the first hackathon for personal ... largest companies in the genomics, tech and health industries ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... 2017 , ... AMRI, a global contract research, development and ... outcomes and quality of life, will now be offering its impurity solutions as ... regulatory requirements for all new drug products, including the finalization of ICH M7 ...
(Date:10/11/2017)... (PRWEB) , ... October 11, 2017 , ... ... any gene in its endogenous context, enabling overexpression experiments and avoiding the use ... with small RNA guides is transformative for performing systematic gain-of-function studies. , ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... will be hosting a Webinar titled, “Pathology is going digital. Is your lab ... digital pathology adoption best practices and how Proscia improves lab economics and realizes ...
(Date:10/11/2017)... ... ... Disappearing forests and increased emissions are the main causes of the evolving air ... living in larger cities are affected by air pollution related diseases. , That is ... globally - decided to take action. , “I knew I had to take action ...
Breaking Biology Technology: