Navigation Links
Gene hunters close in on Lou Gehrig’s disease

.

“This is the first major step toward understanding how genetics may influence the most common form of ALS,?says co-researcher Jeffrey D. Rothstein, M.D., Ph.D., professor in the Department of Neurology at Johns Hopkins. “The results will not only help us to better understand sporadic ALS but also to tailor tools that will reveal therapies for it.?

Traynor cautioned that the 34 SNPs are not guaranteed trail markers for ALS genes. “If you roll dice 555,352 times, you are bound to get lucky by chance alone on some of those throws,?he says. “The next step is to go back and figure out which of these ‘hits?are real and which are false.?

Thousands of other SNPs were more weakly associated with ALS, some of which could turn out to be just as important as those more strongly linked.

Traynor says a follow-up study is in the works that will replicate the research using a similar number of patients and controls. Traynor, who has a joint affiliation with the National Institute of Mental Health in Bethesda, Md., collaborated in this study with lead author Jennifer Schymick and fellow researcher John Hardy, Ph.D., both of the Laboratory of Neurogenetics at the National Institute on Aging in Bethesda. Researchers from the National Institutes of Health, from the Packard Center for ALS Research at Johns Hopkins and from the University of Turin, Italy, also contributed to this study.
'"/>

Source:Johns Hopkins Medical Institutions


Page: 1 2

Related biology news :

1. Study shows big game hunters, not climate change, killed off sloths
2. Good times ahead for dinosaur hunters, according to U of Penn scientists dinosaur census
3. Chemicals in tattoo inks need closer scrutiny
4. Doctors closer to using gene analysis to help trauma patients
5. Proteomics brings researchers closer to understanding microbes that produce acid mine drainage
6. Computers close in on protein structure prediction
7. New results validating Pall prion reduction filter disclosed at ISBT Congress
8. Scientists closer to new cancer detection method
9. Getting close to nature is good for you
10. Scientists observe how a close bond activates the immune system
11. Stroke treatment a step closer after trial
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Gene hunters close Lou Gehrig disease

(Date:9/15/2014)... epilepsy drug to a morphine regimen can result in ... combination can reduce the dosage of the opioid needed ... researchers at Indiana University. , The result could bring ... difficult-to-treat condition often felt in the arms and legs ... a huge unmet need for better treatments for neuropathic ...
(Date:9/15/2014)... for both plants and animals alike. , Understanding just ... lead to the design of better drugs for diabetes ... and vegetables farmers are able to grow. Stanford University ... the cell by piecing together proteins slightly wider than ... To determine the size, shape and orientation of one ...
(Date:9/15/2014)... When this week,s print issue of the journal ... up from New Mexico, Montana and even the Netherlands, ... more and more the norm in these connected times. ... it will produce innovations in biology, medicine, biotechnology and ... this scientist talked with that one, that one knew ...
Breaking Biology News(10 mins):IU study: Combining epilepsy drug, morphine can result in less pain, lower opioid doses 2X-rays unlock a protein's SWEET side 2X-rays unlock a protein's SWEET side 3Collaboration drives achievement in protein structure research 2
... named beneficiaries of the Joshua E. Neimark Memorial Travel ... young children,s interest in insects, an effort to fine-tune ... a way to lower the cost of a key ... financial support to attend America,s largest general scientific conference, ...
... Biologists at UC San Diego have identified the specific region ... development. Their discovery, which appears in a paper in ... is a critical first step for the development of ... leukemia, multiple myeloma, anemia and a host of other diseases ...
... the California Institute of Technology (Caltech) have obtained the ... fruit fly. The workby Michael Dickinson, the ... with postdoctoral scholars Gaby Maimon and Andrew Strawsuggests that ... fly (Drosophila melanogaster) "is in a different and more ...
Cached Biology News:Joshua E. Neimark Memorial Travel Assistance Award winners 2Biologists image birth of blood-forming stem cells in embryo 2Biologists image birth of blood-forming stem cells in embryo 3Caltech researchers obtain first brain recordings from behaving fruit flies 2Caltech researchers obtain first brain recordings from behaving fruit flies 3
(Date:9/16/2014)... SAN DIEGO , Sept. 16, 2014  Biocom, ... life science community, recognizes the 9 th ... to the value of IT technologies in improving our ... California is one of the world,s most ... from EHRs to mobile health applications to genomic testing ...
(Date:9/16/2014)... created a deicing film for radar domes have now ... for glass. , The new work by Rice ... surfaces from windshields to skyscrapers free of ice and ... , The technology was introduced this month in ... Interfaces . , The material is made of ...
(Date:9/16/2014)... Fresne, President and CEO of Egenix, Inc. is pleased to ... its Scientific Advisory Committee. Dr. Vagner, a graduate ... performed research at Embl (European Molecular Biology Laboratory) Heidelberg, ... of health and medical research. He is a Research Director ... France , and at the Gustave Roussy ...
(Date:9/16/2014)... Sept. 16, 2014   Synthetic Biologics, Inc. ... novel anti-infective biologic and drug programs targeting specific ... the completion of the Company,s Investor Day in ... its irritable bowel syndrome (IBS) program, including its ... In the keynote presentation, Mark ...
Breaking Biology Technology:Biocom Recognizes National Health IT Week 2Nanoribbon film keeps glass ice-free 2New Appointment to the Scientific Advisory Committee at Egenix, Inc. 2Synthetic Biologics' Statin-Class Candidate for Constipation-Predominant Irritable Bowel Syndrome Detailed at Company's Investor Day 2Synthetic Biologics' Statin-Class Candidate for Constipation-Predominant Irritable Bowel Syndrome Detailed at Company's Investor Day 3
... April 27 BioRN Cluster Management GmbH presents ... management,s collaborative project, a web-based software to manage complex ... or single companies with an easy-to-use application for the ... the core needs of the different project partners: of ...
... , April 27 A non-profit organization is urging PepsiCo ... amount of its corporate donations.  "Unlike Coca-Cola, Pepsi refuses to divulge the ... Quinlan , President of Parents and Friends of Ex-Gays & Gays (PFOX). ... "This secrecy by ...
... , ... partners with RURO to offer GLP/GMP certified hosting services. , ... Annapolis, MD (Vocus) April 27, 2010 -- ... with laboratory software provider RURO. RURO’s leading edge laboratory applications can now be ...
Cached Biology Technology:Web-Based Management Suite Supports Complex Research Consortia 2Pepsi Urged to Follow Example of Coca-Cola and Stop Hiding Corporate Donations 2Sidus BioData Partners with Life Science Software Provider RuRo 2
... optically clear polystyrene with frosted labeling ... for cell counting. 100% integrity tested. ... new product number, created to easily ... no availability yet, please order under ...
Packaging: package with 500 l Patent/trademark/license (electronic): (r) Registered trademark of Molecular Probes...
... VersaDoc MP 4000 System is a ... system capable of supporting a wide ... chemiluminescence, densitometry, and chemiflourescence. Red, ... imaging of multiplexed fluorescent samples, reducing ...
... hydrophobic barrier pen for immunohistochemistry and in ... frozen or paraffin-embedded tissue sections mounted on ... heat-stable, water-repellent barrier that keeps staining reagents ... of reagents when differentially staining two sections ...
Biology Products: