Navigation Links
Gene controlling circadian rhythms linked to drug addiction

a pattern called bursting, which leads to an usually large dopamine release," Dr. McClung said. "We also found that more dopamine is produced and released in these mice under normal conditions and particularly after exposure to cocaine."

Dr. Eric Nestler, chairman of psychiatry at UT Southwestern and the study's senior author, said the results suggest there may be a link in disruption of circadian rhythms and the tendency to abuse drugs.

"Most work on Clock has focused on the brain's master pacemaker, located in a brain area called the suprachiasmatic nucleus," said Dr. Nestler. "The novelty of Dr. McClung's findings is the role Clock plays in brain reward pathways. The next step is to examine Clock and related genes in human addicts."

Dr. Donald Cooper, assistant professor of psychiatry at UT Southwestern, also contributed to the study, as did researchers from the University of Crete in Heraklion; the Rosalind Franklin University of Medicine and Science in North Chicago; and the Howard Hughes Medical Institute at Northwestern University.

The study was supported by grants from the National Institute on Drug Abuse, the National Institute of Mental Health and the Onassis Public Benefit Foundation.


'"/>

Source:UTSouthwestern


Page: 1 2

Related biology news :

1. Scientists find that protein controls aging by controlling insulin
2. Enzyme affects hypertension by controlling salt levels in body
3. Liquid crystals show promise in controlling embryonic stem cells
4. Important gene controlling tree growth and development found
5. Key gene controlling eye lens development identified
6. Electronic chip, interacting with the brain, modifies pathways for controlling movement
7. Edge density key to controlling gypsy moth spread
8. Key gene controlling kidney development found
9. After a time-shift, mixed signals from the circadian clock
10. The circadian clock: Understanding natures timepiece
11. Temperature regulates circadian clock in zebrafish
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Gene controlling circadian rhythms linked drug addiction

(Date:9/19/2014)... which over thousands of years has adapted to the arctic ... makes the cold dangerous for you. , This is happening ... the cold provoking substance, called nonylphenol, comes from the use ... of being a endocrine disruptor, but when entering the worm ... to protect the cells in its body from cold damage. ...
(Date:9/18/2014)... deep in the primitive brainstem has revealed how we ... School of Medicine and the University at Buffalo School ... second "sleep node" identified in the mammalian brain whose ... produce deep sleep. , Published online in August in ... half of all of the brain,s sleep-promoting activity originates ...
(Date:9/18/2014)... "frequent flyers" program, fruit flies surely would be eligible ... increasing numbers of fruit fly research studies. One fruit ... and another is scheduled launch to the station Sept. ... December. , Fruit flies are biomedical research models studied ... organisms can reveal the basis for health and disease ...
Breaking Biology News(10 mins):Environmental pollutants make worms susceptible to cold 2Environmental pollutants make worms susceptible to cold 3No sedative necessary: Scientists discover new 'sleep node' in the brain 2Buzzing with activity: Fruit flies orbit Earth for science 2Buzzing with activity: Fruit flies orbit Earth for science 3Buzzing with activity: Fruit flies orbit Earth for science 4
... that shows clear evidence of evolution from lower primates ... well have depended in part on hyperactivation of the ... regulating perception, behavior and memory. , They reported that, ... in a regulatory segment of the prodynorphin gene, which ...
... BioSciences, Inc. today announced that data from its ... were presented at the 45th Annual Interscience Conference ... DC. The study represents the first demonstration ... infection by treatment with Sangamo's proprietary zinc finger ...
... ever wondered how the myriad insect forms—beetles, flies, dragonflies, ... Insects make up 75% of all species known. The ... of a combination of one or more factors: a ... an ability to adapt to new environments and exploit ...
Cached Biology News:Key brain regulatory gene shows evolution in humans 2Key brain regulatory gene shows evolution in humans 3Key brain regulatory gene shows evolution in humans 4Sangamo BioSciences demonstrates its ZFP treatment protects cells from HIV infection 2Islands in the Genome Promote Speciation 2
(Date:9/20/2014)... September 20, 2014 MediVet America ... perform a groundbreaking surgery at the specialized Wolvega Horse ... superficial digital flexor tendon was ruptured 90% and her ... injury is a death sentence for a horse. , ... stem cell treatments . This revolutionary regenerative option ...
(Date:9/19/2014)... Life is rarely simple. From crop yields to disease ... usually those considered "complex traits." Just as for heightthe ... a particular human disease are shaped by multiple genetic ... genes involved. To track down such genes, geneticists typically ... a large mouse and a small mouseand then study ...
(Date:9/19/2014)... that use light, rather than electricity, to move ... energy efficiency is a growing concern as chips, ... components of optical circuits light emitters, modulators, ... build. One promising light source for optical chips ... properties when deposited as a single, atom-thick layer. ...
(Date:9/19/2014)...  An entire month is dedicated to one of ... disease (CMT) – a debilitating neuromuscular disease affecting the ... weakness, and foot and hand deformities. CMT affects 1 ... is a progressive disease, and over time patients lose ... such as leg braces, wheelchairs and scooters to get ...
Breaking Biology Technology:World’s first tendon replacement using Nanofiber and activated MediVet Stem Cell Fraction 2World’s first tendon replacement using Nanofiber and activated MediVet Stem Cell Fraction 3Want to link genes to complex traits? Start with more diversity 2Toward optical chips 2Toward optical chips 3September is Charcot-Marie-Tooth (CMT) Awareness Month - Scheduled events, activities and important partnerships announced throughout the month! 2
... Oct. 8 /PRNewswire-FirstCall/ - Oncolytics Biotech Inc.,("Oncolytics") ... completed initial scale up of its manufacturing ... scale up of primary production and downstream ... Council Biotechnology,Research Institute (NRC-BRI) located in Montreal, ...
... Matrox Graphics Inc., the leading,manufacturer of specialized graphics ... Xenia(TM) Series display controller boards with its,ME/CCL medical ... native PCI Express single-slot board with,all-digital, triple-monitor output ... Xenia Series supports resolutions from <1MP to,8MP with ...
... a six-year battle with heart disease that included numerous medications, trips to ... found himself in the Intensive Care Unit at an Ohio hospital. Both ... of a transplant. , ... TUCSON, Ariz. (Business Wire EON) October ...
Cached Biology Technology:Oncolytics Biotech Inc. Completes Initial Scale Up of Manufacturing Process for REOLYSIN(R) to Commercial Scale 2Totoku Europe Chooses Matrox Xenia(TM) Series to Drive Medical Monitors 2 "Put Down the BBQ Ribs, We've Found You a Donor Heart," Nurse Tells Patient : Ohio Father near Death Gets Second Chance at Life with CardioWest&#8482; temporary Total Artificial Heart 2
Mouse monoclonal [MN-8C4] to zona radiata ( Abpromise for all tested applications). Antigen: Purified eggshell proteins (zona radiata proteins and small amounts of zona pellucida proteins) from ...
CCNI Antibody...
...
...
Biology Products: