Navigation Links
Gene Therapy For Parkinson's Disease Moves Forward In Animals

sh its dwindling supply of dopamine, sidetracking the destructive course of Parkinson's disease. But eventually the treatment can backfire.

“Levodopa generally works great for several years, but then it actually starts creating movement problems,?Mandel said. “Our idea is that instead of taking pills that create detrimental fluctuations of L-dopa levels, a continuous, therapeutic dose would be better for you.

As for efforts to reverse impaired movements in rats, scientists used 33 animals with severe dopamine depletion and transferred a gene to provide a source of L-dopa production into the animals' striata. Before receiving the treatment, all animals had limited use in their left paws. After treatment, the animals receiving the therapeutic enzyme mixture show complete recovery in their paws. Researchers say not only did the rats recover substantial degrees of function in their impaired forelimbs, continuous levels of L-dopa were being produced in their brains, blocking side effects.


'"/>

Source:University Of Florida Health Science Center


Page: 1 2 3 4

Related biology news :

1. Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer
2. Novel Therapy Tested in Mice Could Chase Away Cat Allergies
3. Rush Physicians Using Gene Therapy For Heart Patients With Moderate To Severe Chest Pains Who Do Not Benefit From Other Treatments
4. Pathogen-Mimicking Vaccine As Strategy For Cancer Therapy
5. Discovery Promises Simpler Therapy for Sickle Cell Disease
6. Gene Therapy Cures Inherited Liver Disease In Rats
7. Antiretroviral Therapy May Prevent HIV Transmission From Breastfeeding Mothers To Infants
8. HIV Therapy Greatly Extends Life of Key T Cells, Scientists Find
9. Menopause Symptoms May Come Back After Stopping Menopausal Hormone Therapy
10. Newly Discovered Role for Heart Response Enzyme May Yield Better Heart Failure Therapy
11. Scientists detect probable genetic cause of some Parkinsons disease cases
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Gene Therapy For Parkinson Disease Moves Forward Animals

(Date:9/16/2014)... fall marks a new school year, a new football ... Space Station. In September, SpaceX,s Dragon spacecraft is scheduled ... and investigations as part of the company,s fourth contracted ... will be the third suite of research investigations sponsored ... Space (CASIS). With the role of managing the U.S. ...
(Date:9/16/2014)... (KXL) would likely increase oil sands extraction, according to ... non-profit organization Near Zero. The results are detailed in ... both supporters and opponents of the pipeline. ... to significantly higher greenhouse gas emissions, with the exact ... "This report examines three main scenarios discussed by participants ...
(Date:9/16/2014)... votes for independence later this week, its Government could ... that fracking is necessary, research has revealed. , The ... public perception of shale gas extraction in the UK ... north of the border are the least supportive of ... in the University,s School of Geography, said: "The clear ...
Breaking Biology News(10 mins):CASIS research set for launch aboard SpaceX mission to space station 2CASIS research set for launch aboard SpaceX mission to space station 3Keystone XL would likely raise oil sands production and greenhouse gas emissions 2Scottish people most sceptical on fracking, survey shows 2Scottish people most sceptical on fracking, survey shows 3
... Medicine and University of Crete School of Medicine researchers ... a molecular mechanism that dynamically alters the strength of ... the development of drug therapies for the cognitive deficits ... bipolar disorder, or attention deficit hyperactivity disorder (ADHD). ...
... novel gene mutation that causes X-linked mental retardation for ... to an article to be published electronically on Tuesday, ... Genetics. , Investigators F. Lucy Raymond (Cambridge Institute ... Patrick S. Tarpey (Wellcome Trust Sanger Institute, Hixton, UK) ...
... the University of California, San Diego and the University ... of estimated plant species richness. Covering several hundred thousand ... most extensive map of the distribution of biodiversity on ... study published in this week's early online issue of ...
Cached Biology News:Brain networks strengthened by closing ion channels 2Brain networks strengthened by closing ion channels 3Severe mental retardation gene mutation identified 2Biologists produce global map of plant biodiversity 2
(Date:9/17/2014)... MARLBOROUGH, Mass. , Sept. 17, 2014 /PRNewswire/ ... ), a biotechnology company focused on discovering, developing ... needs using RNA-targeted technologies, today announced that it has ... Patent and Trademark Office on its unique delivery ... ® ) to phagocytic cells for the treatment ...
(Date:9/17/2014)... 17, 2014 Escape Alert, LLC . filed ... which will alert owners if their pet has escaped and enable ... implanted microchip in the pet’s body. This is the first ... pets have been around for many years, they are passive until ... to track a pet’s location or alert the owner that the ...
(Date:9/17/2014)... September 17, 2014 The Pistoia ... to lowering the barriers to innovation in life ... appointment of Carmen Nitsche as Executive Director Business ... expand its global reach. , Carmen joins the ... President, Corporate Development. At Accelrys, she managed various ...
(Date:9/16/2014)... YORK , Sept. 16, 2014 This report ... the following Product Segments: Software, Hardware, and Biocontent. The report ... , Japan , Europe ... America , and Rest of World. Annual estimates and ... a seven-year historic analysis is provided for these markets. Market ...
Breaking Biology Technology:RXi Pharmaceuticals Strengthens Intellectual Property Portfolio 2RXi Pharmaceuticals Strengthens Intellectual Property Portfolio 3RXi Pharmaceuticals Strengthens Intellectual Property Portfolio 4Implantable Microchip for Pets with GPS Tracking - Patent Filed by Escape Alert, LLC. 2Implantable Microchip for Pets with GPS Tracking - Patent Filed by Escape Alert, LLC. 3Pistoia Alliance Expands Business Development with Appointment of Carmen Nitsche 2Global Bioinformatics Industry 2Global Bioinformatics Industry 3Global Bioinformatics Industry 4Global Bioinformatics Industry 5Global Bioinformatics Industry 6Global Bioinformatics Industry 7Global Bioinformatics Industry 8Global Bioinformatics Industry 9Global Bioinformatics Industry 10Global Bioinformatics Industry 11Global Bioinformatics Industry 12Global Bioinformatics Industry 13Global Bioinformatics Industry 14Global Bioinformatics Industry 15Global Bioinformatics Industry 16Global Bioinformatics Industry 17Global Bioinformatics Industry 18Global Bioinformatics Industry 19Global Bioinformatics Industry 20Global Bioinformatics Industry 21Global Bioinformatics Industry 22Global Bioinformatics Industry 23
... Allows Accurate Marketing Claims Designed with Input from,Entire ... nation,s leading livestock,cloning companies announced today a tracking ... allow food companies to identify cloned animals,when they ... program was developed through extensive cooperative discussions,over the ...
... MATEO, Calif., Dec. 19 BioForm Medical,Inc. (Nasdaq: ... will present a company overview at the upcoming 26th ... BioForm,Medical,s presentation will take place on Monday, January 7th, ... Westin St. Francis Hotel in San Francisco,CA., A ...
... Holdings, Inc. (OTC,Bulletin Board: HTWO) announced today that ... Mirant Energy Trading LLC, a subsidiary of Mirant ... biofuel technology in utility,scale power generation applications., ... biofuel for a gas,turbine test program that will ...
Cached Biology Technology:Top U.S. Cloning Companies Announce New System to Track Cloned Livestock 2BioForm Medical to Present at the 2008 JPMorgan Healthcare Conference on January 7, 2008 2H2Diesel Holdings Announces Test Burn Agreement With Mirant Corp. 2H2Diesel Holdings Announces Test Burn Agreement With Mirant Corp. 3
... to the maintenance of appropriate levels ... important and diverse as those involved ... stress response, antigen presentation, modulation of ... cell cycle regulation, transcription, and signalling ...
... includes 1. Scanning of gel(s) 2. ... tryptic in-gel digestion and peptide extraction ... 5. Acquisition of PMF (Peptide Mass ... TOF/TOF) 6. Acquisition of PFF (Peptide ...
... The Vibratome Company has joined forces with ... the Vibratome 411301 Tissue Chopper. This tissue ... sections of tissue for metabolic experiments and ... irregular specimens available at biopsy or from ...
... The ProteinChip Antibody ... assay development and optimization ... evaluate antibody-antigen interactions. This ... and differentiation of multiple ...
Biology Products: