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Gambling monkeys give insight into neural machinery of risk

might be more risk prone and impulsive," said Platt. "Disturbances in such neurotransmitter systems might be the basis of pathological conditions like pathological gambling, obsessive-compulsive disorder and depression. We can do pharmacological manipulation of the serotonin system in monkeys to see how it influences risk perception and risk preferences, and whether we see changes at the level of the single neurons that we're studying."

What's more, said Platt, the studies with monkeys can guide studies in mice, in which scientists can make genetic alterations in the mice and study the behavioral effects of those alterations. Such studies could contribute to understanding of the genetic basis of compulsive behaviors and other such behavioral disorders.


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Source:Duke University Medical Center


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