Navigation Links
Fundamental discovery -- Bone fracture

A startling discovery about the properties of human bone has been made by scientists at the University of California, Santa Barbara.

The scientists describe their results –?finding a sort of "glue" in human bone –?in the cover story of the August issue of the international scientific journal, Nature Materials.

The article was published on-line on July 17. It describes how healthy bone resists fracture and how unhealthy bone fractures at the molecular level. Included with the article are the highest resolution images of bone ever published, which reveal the location of the adhesive or "glue" that holds together mineralized collagen fibrils (protein fibers) of bone.

The glue appears to contain "springs" that uncoil when the bone is stressed, helping the bone to absorb shock. When the stress is relaxed, they coil back to their original structure.

The possible implications for human health are important, explained Georg E. Fantner, a UCSB doctoral student in physics and first author of the report. "The findings may lead to therapy for bone fracture, or even to prevention," he said.

Working in the physics laboratory of Professor Paul K. Hansma, in collaboration with the UCSB labs of Professors Daniel E. Morse and Galen D. Stucky, the interdisciplinary group of scientists spent several years tracking down where the glue was located in bone, and how it worked.

"Before this research, it was well known that the mechanical properties of bone depended on mineral particles and on collagen fibrils," said Hansma. "The picture of bone was that it consisted of these collagen fibrils coated with tiny mineral crystals only a few atoms thick. What we found is that there is a glue in bone that holds these mineralized collagen fibrils together, and this glue works along the same principles that our interdisciplinary research group found in abalone shells. This glue involves sacrificial bonds (with hidden length) that uncoil when the bone is
'"/>

Source:University of California - Santa Barbara


Page: 1 2 3

Related biology news :

1. Fundamental Finding Yields Insight into Stem Cells, Cancer; Opens Door to Drug Discovery
2. Protein discovery could unlock the secret to better TB treatment
3. Purdue proves concept of using nano-materials for drug discovery
4. UCSD discovery may help extend life of natural pesticide
5. Leprosy microbes lead scientists to immune discovery
6. Biochemists report discovery of structure of major piece of telomerase; implications for cancer
7. Researchers make surprise discovery that some neurons can transmit three signals at once
8. Important discovery about second most fatal cancer
9. Harmless virus may hold key to more effective HIV drug discovery
10. Genetic discovery could lead to drought-resistant plants
11. Gene discovery sheds light on causes of rare disease, cancer
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Fundamental discovery Bone fracture

(Date:8/19/2014)... Some infants born with neonatal abstinence syndrome (NAS) ... difficult time going through withdrawal than others, but ... genetic and epigenetic (when genes are turned on ... potential factors, researchers at Boston University School of ... a first of its kind study to identify ...
(Date:8/19/2014)... Center at San Antonio and The University of Texas ... more than $750,000 in grants through the San Antonio ... 2003, SALSI is a model of how a general ... join forces for greater research and graduate education. , ... on public health issues and diseases of global impact. ...
(Date:8/19/2014)... 2014A new ovoid structure discovered in the Nakhla Martian ... variety of minerals, and shows evidence of undergoing a ... the permafrost and mixing of surface and subsurface fluids. ... analytical studies to determine the origin of this new ... ovoid formed, point to the most likely conclusion, and ...
Breaking Biology News(10 mins):In-utero methadone, Subutex exposure could alter gene expression, cause severe Neonatal Abstience Syndrome 2San Antonio Life Sciences Institute awards $750,000 to innovators 2San Antonio Life Sciences Institute awards $750,000 to innovators 3Life on Mars? Implications of a newly discovered mineral-rich structure 2
... the ends of bones where they meet in a ... can lead to degenerative disease. Treatments and experimental approaches ... but currently there is no method to fully restore ... delivery of therapeutic proteins to the injured site is ...
... of good advice to help us avoid becoming obese, such ... surprising piece of advice based on a promising area of ... that certain viruses may cause obesity, in essence making obesity ... a new study, "Adipogenic potential of multiple human adenoviruses in ...
... depression-like social withdrawal syndrome, repeated defeat by dominant animals ... its brain that could help to explain why depression ... the National Institutes of Health's (NIH) National Institute of ... this animal model of depression, silencer molecules turned off ...
Cached Biology News:Stem cells from muscles can repair cartilage 2Stem cells from muscles can repair cartilage 3Contagious obesity? Identifying the human adenoviruses that may make us fat 2Contagious obesity? Identifying the human adenoviruses that may make us fat 3Contagious obesity? Identifying the human adenoviruses that may make us fat 4Depression model leaves mice with molecular scar 2
(Date:8/20/2014)... Bulgaria (PRWEB) August 20, 2014 ... was released today including improvements to the enterprise ... and connectors for Lucene, SOLR and Elasticsearch. This ... for this high performance triplestore – GraphDB™ was ... interested in deploying the only mature enterprise resilient ...
(Date:8/19/2014)... Columbia, Md. (PRWEB) August 19, 2014 ... integrated liquid chromatography systems, Prominence-i and Nexera-i, adding ... UHPLC systems. Combining excellent functionality, an intuitive operating ... performance and a more efficient workflow for conventional ... systems feature innovative, intuitive and intelligent design so ...
(Date:8/19/2014)... DANVILLE, Pa. , Aug. 19, 2014 ... C has been nominated for a Centers for Disease ... to addressing a major public health concern. ... Health System, is one of a team of researchers ... (CDC) Charles C. Shepard Science Award for Data Methods ...
(Date:8/19/2014)... 19, 2014 Research and Markets  has announced ... - Global Strategic Business Report" report to their offering. ... Solid Oxide Fuel Cells (SOFCs) in US$ Thousands. The report ... , Europe , Asia-Pacific ... are provided for the period 2012 through 2020. Market data ...
Breaking Biology Technology:Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 2Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 3Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 4Shimadzu’s New i-Series Integrated Liquid Chromatography Systems Provide Laboratories Wider Range of Analytical Capabilities 2Shimadzu’s New i-Series Integrated Liquid Chromatography Systems Provide Laboratories Wider Range of Analytical Capabilities 3Geisinger investigator nominated for federal award 2Geisinger investigator nominated for federal award 3Global Solid Oxide Fuel Cells (SOFCs) - Strategic Business Report 2014 2
... a new generation of piezoelectric nanogenerators with two types ... to be the first self-powered nanometer-scale sensing devices that ... The new devices can measure the pH of liquids ... current produced from mechanical energy in the environment. ...
... FRANCISCOScientists at Carnegie Mellon University,s Department of Chemistry and ... state-of-the-art in live cell fluorescent imaging by developing a ... from violet to the near-infrared. The new technology, ... of individual proteins in living cells in real time. ...
... ... of Business Award in the Commercial Site category by the Small Business Commerce Association (SBCA). ... identified through statistical research and monthly surveys. , ... Emeryville, CA (PRWEB) March 25, 2010 -- BioSoteria, Inc ., a ...
Cached Biology Technology:Researchers use improved nanogenerators to power sensors based on zinc oxide nanowires 2Researchers use improved nanogenerators to power sensors based on zinc oxide nanowires 3Carnegie Mellon scientists create rainbow of fluorescent probes 2Drug Safety Firm BioSoteria Receives 2009 Best of Business Award 2
Mouse monoclonal [N7519] to NR0B2 ( Abpromise for all tested applications). Antigen: E.coli expressed recombinant full length protein (Human) NR0B2 Entrez Gene ID: 8431 Swiss Protein ID: ...
Rabbit polyclonal to BCA1 ( Abpromise for all tested applications). Antigen: Generated using E.coli expressed mouse BCA1. Entrez GeneID: 10563 SWISS Protein ID: O43927...
PKC Sampler Kit 10 mu g each...
Purified anti-SOCS3...
Biology Products: