Navigation Links
Friendly bacteria in humans may protect against HIV

Scientists have identified good bacteria already living in some humans that target and trap HIV and may protect against infection. They report their findings today at the 2005 American Society for Microbiology Beneficial Microbes Conference.

"I believe every life form has its natural enemy, and HIV should not be the exception," says Dr. Lin Tao, Associate Professor of the Department of Oral Biology, College of Dentistry, University of Illinois at Chicago. "If we can find its natural enemy, we can control the spread of HIV naturally and cost-effectively, just as we use cats to control mice."

The bacteria are strains of lactobacillus, commonly found colonizing the oral and vaginal cavities of humans. They do not cause disease. They target HIV because the virus is coated with the sugar mannose, which they use as a food source.

"Different bacteria have different sugar preferences," says Tao. "To block HIV, however, we needed to find bacteria that prefer the unusual sugar mannose and thus can capture it."

To identify bacteria that target mannose, Tao and his colleagues isolated oral and vaginal lactobacilli from healthy humans and tested the ability of different strains to bind to baker's yeast, another microorganism coated with mannose-rich sugars. They found a small group of lactobacilli that bound to mannose and further testing against HIV revealed two strains that specifically trapped the virus and blocked infection.

Due to high rates of mutation, repeated attempts at developing a vaccine to protect against HIV have failed. Inoculating the major mucosal surfaces where HIV transmission occurs with the HIV-capturing lactobacilli may provide a safe and cost-efficient method for preventing the spread of HIV, says Tao.

"This method can protect infants against HIV in breast milk and women against HIV upon sexual contact unobtrusively and inconspicuously via fermented foods or feminine products," says Tao. "If the method can be successfully developed and applied, the global spread of HIV can be controlled rapidly, effectively and safely."

"The major roadblock in the development of this technology is the lack of financial support. Drug companies and venture capitalists are not interested because the beneficiary populations are infants and women in poor countries," says Tao. He is currently seeking sponsorship from charities or philanthropists to develop this technology.


'"/>

Source:American Society for Microbiology


Related biology news :

1. Spider Venom Could Yield Eco-Friendly Insecticides
2. Friendly bacteria in chewing gum that bites back
3. Friendly bacteria in alcoholic milkshake could fight food allergies
4. Anti-bacterial additive widespread in U.S. waterways
5. A bacterial genome reveals new targets to combat infectious disease
6. Discovery of key proteins shape could lead to improved bacterial pneumonia vaccine
7. Scientists discover that host cell lipids facilitate bacterial movement
8. Family trees of ancient bacteria reveal evolutionary moves
9. Drug-resistant bacteria on poultry products differ by brand
10. Programmable cells: Engineer turns bacteria into living computers
11. NASA links nanobacteria to kidney stones and other diseases
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/22/2017)... Optimove , provider of the ... as 1-800-Flowers and AdoreMe, today announced two new ... Using Optimove,s machine learning algorithms, these features allow ... recommendations to their customers based not just on ... intent drawn from a complex web of data ...
(Date:3/16/2017)... Germany , March 16, 2017 CeBIT 2017 - Against identity ... Continue Reading ... Used combined in one project, multi-biometric solutions provide ... Used ... Systems) ...
(Date:3/7/2017)... , March 7, 2017 Brandwatch , the ... by The Prince,s Trust to uncover insights to support ... The Trust. The UK,s leading youth charity will be ... campaign results and get a better understanding of the topics and ... ...
Breaking Biology News(10 mins):
(Date:3/23/2017)... March 23, 2017 According to a report ... derivatives market is fragmented due to the presence of a large pool ... Thermo Fisher , and Sigma-Aldrich, compete with each other in ... collectively, held more than 76% of this market in 2016.  ... As of now, a ...
(Date:3/23/2017)... ... March 23, 2017 , ... ... today announced the hire of Dr. Sigmund “Sig” Floyd as Vice President ? ... partnerships and joint development activities. , “Dr. Floyd’s career has spanned 30 years ...
(Date:3/22/2017)... 2017  Ascendis Pharma A/S (Nasdaq: ASND), a ... to address significant unmet medical needs in rare ... year ended December 31, 2016. ... as we broadened our pipeline and pursued our ... company with an initial focus on endocrinology," said ...
(Date:3/22/2017)... 2017 Oramed Pharmaceuticals Inc. (NASDAQ: ... ), a clinical-stage pharmaceutical company focused ... announced today that Dr. Miriam Kidron , ... titled, "Oral Insulin for Diabetes Treatment: Bypassing the ... and Peptide Therapeutics (OPT) Boston Conference in ...
Breaking Biology Technology: