Navigation Links
Friendly bacteria in humans may protect against HIV

Scientists have identified good bacteria already living in some humans that target and trap HIV and may protect against infection. They report their findings today at the 2005 American Society for Microbiology Beneficial Microbes Conference.

"I believe every life form has its natural enemy, and HIV should not be the exception," says Dr. Lin Tao, Associate Professor of the Department of Oral Biology, College of Dentistry, University of Illinois at Chicago. "If we can find its natural enemy, we can control the spread of HIV naturally and cost-effectively, just as we use cats to control mice."

The bacteria are strains of lactobacillus, commonly found colonizing the oral and vaginal cavities of humans. They do not cause disease. They target HIV because the virus is coated with the sugar mannose, which they use as a food source.

"Different bacteria have different sugar preferences," says Tao. "To block HIV, however, we needed to find bacteria that prefer the unusual sugar mannose and thus can capture it."

To identify bacteria that target mannose, Tao and his colleagues isolated oral and vaginal lactobacilli from healthy humans and tested the ability of different strains to bind to baker's yeast, another microorganism coated with mannose-rich sugars. They found a small group of lactobacilli that bound to mannose and further testing against HIV revealed two strains that specifically trapped the virus and blocked infection.

Due to high rates of mutation, repeated attempts at developing a vaccine to protect against HIV have failed. Inoculating the major mucosal surfaces where HIV transmission occurs with the HIV-capturing lactobacilli may provide a safe and cost-efficient method for preventing the spread of HIV, says Tao.

"This method can protect infants against HIV in breast milk and women against HIV upon sexual contact unobtrusively and inconspicuously via fermented foods or feminine products," says Tao. "If the method can be successfully developed and applied, the global spread of HIV can be controlled rapidly, effectively and safely."

"The major roadblock in the development of this technology is the lack of financial support. Drug companies and venture capitalists are not interested because the beneficiary populations are infants and women in poor countries," says Tao. He is currently seeking sponsorship from charities or philanthropists to develop this technology.


'"/>

Source:American Society for Microbiology


Related biology news :

1. Spider Venom Could Yield Eco-Friendly Insecticides
2. Friendly bacteria in chewing gum that bites back
3. Friendly bacteria in alcoholic milkshake could fight food allergies
4. Anti-bacterial additive widespread in U.S. waterways
5. A bacterial genome reveals new targets to combat infectious disease
6. Discovery of key proteins shape could lead to improved bacterial pneumonia vaccine
7. Scientists discover that host cell lipids facilitate bacterial movement
8. Family trees of ancient bacteria reveal evolutionary moves
9. Drug-resistant bacteria on poultry products differ by brand
10. Programmable cells: Engineer turns bacteria into living computers
11. NASA links nanobacteria to kidney stones and other diseases
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/31/2016)... 31, 2016  Genomics firm Nabsys has completed a ... Barrett Bready , M.D., who returned to the company ... technical leadership team, including Chief Technology Officer, John ... Steve Nurnberg and Vice President of Software and Informatics, ... Dr. Bready served as CEO of Nabsys ...
(Date:3/23/2016)... , March 23, 2016 ... Interesse erhöhter Sicherheit Gesichts- und Stimmerkennung mit ... Inc. (NASDAQ: MESG ), ein ... dass das Unternehmen mit SpeechPro zusammenarbeitet, um ... der Finanzdienstleistungsbranche, wird die Möglichkeit angeboten, im ...
(Date:3/22/2016)... , PROVO and ... Newborn Screening Ontario (NSO), which operates the highest sample ... molecular testing, and Tute Genomics and UNIConnect, leaders in ... respectively, today announced the launch of a project to ... (NGS) testing panel. NSO has been ...
Breaking Biology News(10 mins):
(Date:5/25/2016)... ... May 25, 2016 , ... Lady had been battling ... her cruciate ligament in her left knee. Lady’s owner Hannah sought the help of ... board-certified veterinary surgeon, to repair her cruciate ligament and help with the pain of ...
(Date:5/24/2016)... May 24, 2016   MedyMatch Technology Ltd ., the ... intelligence, real-time decision support tools in the emergency room, announced ... 2016 Israeli Advanced Technology Industries (IATI) BioMed Conference. ... 15th National Life Sciences and Technology Week, and ... Intercontinental Hotel in Tel Aviv, Israel . ...
(Date:5/23/2016)... ... ... need for blood donations in South Texas and across the nation is growing. , But ... blood donations are on the decline. In fact, donations across the country are at their ... Texas in the last four years alone. , There is no substitute for blood. , ...
(Date:5/23/2016)... -- Oxitec CEO Hadyn Parry will ... ET before the United States House Committee on Science, Space ... in controlling the spread of the Aedes aegypti ...      (Logo: http://photos.prnewswire.com/prnh/20150630/227348 ) Oxitec has ... Trials in Brazil , Panama ...
Breaking Biology Technology: