Navigation Links
Friendly bacteria in humans may protect against HIV

Scientists have identified good bacteria already living in some humans that target and trap HIV and may protect against infection. They report their findings today at the 2005 American Society for Microbiology Beneficial Microbes Conference.

"I believe every life form has its natural enemy, and HIV should not be the exception," says Dr. Lin Tao, Associate Professor of the Department of Oral Biology, College of Dentistry, University of Illinois at Chicago. "If we can find its natural enemy, we can control the spread of HIV naturally and cost-effectively, just as we use cats to control mice."

The bacteria are strains of lactobacillus, commonly found colonizing the oral and vaginal cavities of humans. They do not cause disease. They target HIV because the virus is coated with the sugar mannose, which they use as a food source.

"Different bacteria have different sugar preferences," says Tao. "To block HIV, however, we needed to find bacteria that prefer the unusual sugar mannose and thus can capture it."

To identify bacteria that target mannose, Tao and his colleagues isolated oral and vaginal lactobacilli from healthy humans and tested the ability of different strains to bind to baker's yeast, another microorganism coated with mannose-rich sugars. They found a small group of lactobacilli that bound to mannose and further testing against HIV revealed two strains that specifically trapped the virus and blocked infection.

Due to high rates of mutation, repeated attempts at developing a vaccine to protect against HIV have failed. Inoculating the major mucosal surfaces where HIV transmission occurs with the HIV-capturing lactobacilli may provide a safe and cost-efficient method for preventing the spread of HIV, says Tao.

"This method can protect infants against HIV in breast milk and women against HIV upon sexual contact unobtrusively and inconspicuously via fermented foods or feminine products," says Tao. "If the method can be successfully developed and applied, the global spread of HIV can be controlled rapidly, effectively and safely."

"The major roadblock in the development of this technology is the lack of financial support. Drug companies and venture capitalists are not interested because the beneficiary populations are infants and women in poor countries," says Tao. He is currently seeking sponsorship from charities or philanthropists to develop this technology.


'"/>

Source:American Society for Microbiology


Related biology news :

1. Spider Venom Could Yield Eco-Friendly Insecticides
2. Friendly bacteria in chewing gum that bites back
3. Friendly bacteria in alcoholic milkshake could fight food allergies
4. Anti-bacterial additive widespread in U.S. waterways
5. A bacterial genome reveals new targets to combat infectious disease
6. Discovery of key proteins shape could lead to improved bacterial pneumonia vaccine
7. Scientists discover that host cell lipids facilitate bacterial movement
8. Family trees of ancient bacteria reveal evolutionary moves
9. Drug-resistant bacteria on poultry products differ by brand
10. Programmable cells: Engineer turns bacteria into living computers
11. NASA links nanobacteria to kidney stones and other diseases
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/30/2016)... 2016  higi SH llc (higi) announced today ... national brands, industry thought-leaders and celebrity influencers looking ... for taking steps to live healthier, more active ... higi has built the largest self-screening health station ... people who have conducted over 185 million biometric ...
(Date:11/28/2016)... Nov. 28, 2016 "The ... of 16.79%" The biometric system market is in ... in the near future. The biometric system market is ... 2022, at a CAGR of 16.79% between 2016 and ... of biometric technology in smartphones, rising use of biometric ...
(Date:11/21/2016)... , Nov. 21, 2016   Neurotechnology ... object recognition technologies, today announced that the MegaMatcher ... cards was submitted for the NIST Minutiae ... passed all the mandatory steps of the evaluation ... is a continuing test of fingerprint templates used ...
Breaking Biology News(10 mins):
(Date:12/2/2016)... OF PRUSSIA, PA (PRWEB) , ... December 01, 2016 , ... ... research is through industry-wide collaboration, standardization and a beautiful technology experience. All three tenets ... convened more than 100 clinical trial leaders from over 40 sponsor, CRO and site ...
(Date:12/2/2016)... ... December 02, 2016 , ... Robots will storm the ... on December 3rd, 2016. The event, which is held on the United Nations International ... Americans with Disabilities back into the workplace. Suitable Technologies is partnering with NTI to ...
(Date:12/2/2016)... , Dec. 2, 2016 /PRNewswire/ - bioLytical Laboratories, a world leader in rapid infectious ... Kenya,s Pharmaceutical Association members. (Photo: http://photos.prnewswire.com/prnh/20161201/444905 ) ... ... , , ... the Kenya Pharmaceutical Association (KPA) to introduce the INSTI HIV Self Test to 350 ...
(Date:11/30/2016)... November 30, 2016 The global ... players hold a dominant share in the overall market. ... International, Inc., and Merck KGaA, held a lion,s share ... Market Research observes that these companies are expected to ... products that are do not require rabbit pyrogen testing ...
Breaking Biology Technology: