Navigation Links
Forsyth scientists find three bacteria associated with oral cancer

ists compared bacterial samples from the saliva of 229 healthy subjects with samples from 45 patients who had been diagnosed with oral cancer. The team found elevated levels of three bacterial species (C. gingivalis, P. melaninogenica and S. mitis) in oral cancer patients. The scientists obtained similar findings when they controlled for gender, age, and smoking history.

According to Mager, "Those results led us to hypothesize that the three species could serve as diagnostic indicators for OSCC. And, in fact, we found that elevated salivary counts of the three bacteria correctly identified 80% of individuals with oral cancer and 83% of controls."

If their findings are replicated in future studies, the Forsyth team envisions a simple saliva test that could be administered by dental technicians in large screenings, mailed to a diagnostic center, and returned to doctors or dentists within several days.

The need for screening
Government statistics show that, every year, some 30 thousand US residents are diagnosed with oral cancer. Of those diagnosed, more than 90 per cent are found to have OSCC. If discovered and treated early, OSCC has a five-year survival rate of 80-to-90 percent. But 60 percent of OSCC cases are not diagnosed until the later stages and fewer than 54 per cent of individuals diagnosed in those stages live for five years¡Xplacing OSCC among the deadliest of cancers.

"Far too many people are not diagnosed until their oral cancer is in its advanced stages," Mager said. In part, that is because, in its early stages, oral cancer may be asymptomatic or mimic benign conditions, so those who have it do not seek dental or medical care. "A saliva test would be an easy, non-invasive way to diagnose or monitor patients."

Until such a test exists, Mager added, "I cannot overemphasize how important it is for every adult to be examined by a dental or medical health professional for signs of oral cancer at least once a yea
'"/>

Source:The Forsyth Institute


Page: 1 2 3

Related biology news :

1. New understanding of regeneration gained by Forsyth scientists
2. Forsyth scientists gain greater understanding of how embryos differentiate left from right
3. Wisconsin scientists grow critical nerve cells
4. UCSB scientists probe sea floor venting to gain understanding of early life on Earth
5. UAB scientists discover the origin of a mysterious physical force
6. Fox Chase Cancer Center scientists identify immune-system mutation
7. Weizmann Institute scientists develop a new approach for directing treatment to metastasized prostate cancer in the bones.
8. U-M scientists find genes that control growth of common skin cancer
9. UCLA scientists transform HIV into cancer-seeking missile
10. RNA project to create language for scientists worldwide
11. Carnegie Mellon scientists develop tool that uses MRI to visualize gene expression in living animals
Post Your Comments:
(Date:7/31/2014)... Spain, France, and the U.S. has discovered and ... definitive member of the tribe Omaliini that has ... description were made possible through the use of ... allows the detailed study of otherwise invisible specimens ... in the journal Annals of the Entomological ...
(Date:7/31/2014)... photovoltaic effect in 1839, humankind has sought to further ... own purposes. In a new research report published in ... Journal , scientists may have uncovered a new ... on a naturally occurring combination of lipids that have ... time and across speciessuggests that this specific natural combination ...
(Date:7/31/2014)... Hibiscus flowers- they are an iconic symbol of ... in the landscape. Some, like Hawaii,s State Flower- ... Only a relatively few botanists and Hawaiian conservation ... and intriguing related group of plants known as ... Brother of Hibiscus species are in fact highly ...
Breaking Biology News(10 mins):Scientists shine bright new light on how living things capture energy from the sun 2Brother of Hibiscus is found alive and well on Maui 2
... millions the number of poor forced to seek new ... intense dust storms plaguing many areas menace the health ... a new report. , Thick storms rising out of ... Japan and even reduce air quality over North America, ...
... nerve cells to trees -- some are short and bushy ... branches coming out of one or two main trunks. Different ... to discover how these dissimilar patterns come about and why. ... Rutgers, The State University of New Jersey, examines the role ...
... today that regions of the human genome have been ... specific time-points during evolution. It appears that long periods ... accretion of duplicated DNA fragments, are "punctuated" by relatively ... time that such temporal bias has been documented for ...
Cached Biology News:Millennium Ecosystem Assessment: Many of 2 billion dryland dwellers at risk as land degrades 2Millennium Ecosystem Assessment: Many of 2 billion dryland dwellers at risk as land degrades 3Millennium Ecosystem Assessment: Many of 2 billion dryland dwellers at risk as land degrades 4Snapin: A protein with therapy potential for autism 2'Punctuated' evolution in the human genome 2'Punctuated' evolution in the human genome 3
(Date:7/31/2014)... July 31, 2014 CollabRx, Inc. (NASDAQ: ... therapeutic decision-making in oncology, today announced that it will ... to discuss the Company's financial results for the first ... about the business in the current fiscal year. , ... on Thursday, August 14, 2014, at 5 p.m. EDT ...
(Date:7/31/2014)... Diego, CA (PRWEB) July 31, 2014 ... announced today the integration of Omicsoft’s Array Suite with ... both platforms will be able to send data in ... integration works with all versions of tranSMART including the ... the art statistics, visualization and storage for the analysis ...
(Date:7/31/2014)... SoundConnect , an award ... proud to announce the addition of Adobe Connects ... elearning tools to quickly deploy and manage online ... tools for desktop and mobile learning solutions. , ... perfect online training solution, enabling organizations to deploy, ...
(Date:7/30/2014)... PARIS , July 30, 2014  Regeneron ... NYSE: SNY) today announced that the Companies intend to ... pediatric disease priority review voucher in connection with the ... review voucher entitles the holder to designate a BLA ... review from the filing date instead of the standard ...
Breaking Biology Technology:CollabRx, Inc. Schedules First Quarter Fiscal Year 2015 Financial Conference Call and Business Update 2Rancho BioSciences, in Partnership with Omicsoft, have Integrated Array Suite with tranSMART 2Rancho BioSciences, in Partnership with Omicsoft, have Integrated Array Suite with tranSMART 3SoundConnect Enhances Portfolio with Adobe Connect Learning Management System (LMS) 2Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 2Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 3Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 4Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 5Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 6
... Ohio Scientists are using the engineering technology ... design 3-D models for the replacement of delicate ... or trauma. The researchers, combining engineering ... technique called topological optimization to design an experimental ...
... - Ocean Nutrition Canada (ONC) supplier of the most trusted source ... acquisition of the exclusive global marketing and distribution rights to GAT ... , , ... acquired the rights to exclusive use of GAT,s unique and patented ...
... NEW YORK , July 12 ... or the "Company"), an international,biopharmaceutical company with operations in ... has been awarded a $700,000 contract from ... Advanced Technology,Research Center (USAMRMC-TATRC) under U.S. Army Medical Research ...
Cached Biology Technology:High-performance engineering used to design facial bone replacements 2High-performance engineering used to design facial bone replacements 3Ocean Nutrition Canada Announces Acquisition of Exclusive License to GAT Food Essentials, Omega-3 Microencapsulation-Emulsion Technology 2Ocean Nutrition Canada Announces Acquisition of Exclusive License to GAT Food Essentials, Omega-3 Microencapsulation-Emulsion Technology 3NeoStem to Receive $700,000 from the U.S. Army's Medical Research and Materiel Command to Advance Adult Stem Cell Therapies in Treating Traumatic Wounds 2NeoStem to Receive $700,000 from the U.S. Army's Medical Research and Materiel Command to Advance Adult Stem Cell Therapies in Treating Traumatic Wounds 3NeoStem to Receive $700,000 from the U.S. Army's Medical Research and Materiel Command to Advance Adult Stem Cell Therapies in Treating Traumatic Wounds 4NeoStem to Receive $700,000 from the U.S. Army's Medical Research and Materiel Command to Advance Adult Stem Cell Therapies in Treating Traumatic Wounds 5
... Colorimetric Detection System is intended for use ... generated by an in-house validated in vitro ... of interest. • ... a hybridization capture assay designed to detect ...
... is optimized for maximum packaging efficiencies of cDNA ... l vector. Using a test insert with Novagen's ... (> 4 x 10^8 pfu/g ligated l control ... extremely easy to use; simply add up to ...
BD BioCoat Laminin 150 mm Culture Dishes...
MAb to Desmoplakin I & II Desmoplakin I & II...
Biology Products: