Navigation Links
First frozen egg baby born in Canada

The McGill University Health Center (MUHC) in Montreal is pleased to announce the first successful birth in Canada resulting from frozen eggs. A team led by Professor Seang Lin Tan, Chair of the Department of Obstetrics and Gynecology at McGill University and Director of the McGill Reproductive Centre at the MUHC in Montreal confirmed the birth of a healthy baby boy, weighing 3740grams on April 29. "We are the first in-vitro fertilization (IVF) Centre in Canada to achieve this success," says Dr. Tan. "This is fantastic news for both the family and for fertility health research and we would like to congratulate the parents on the birth of their first child."

The mother, a 26-year-old patient of the McGill Reproductive Centre, had suffered from infertility for two years. Initially, she planned to undergo treatment with ovarian stimulation and intra-uterine insemination (IUI). Because she produced too many follicles in her ovaries, the treatment cycle had to be cancelled because of a high risk of multiple-fetal pregnancy. As an alternative treatment, she had eggs collected from her ovaries, which were then frozen in liquid nitrogen at ?96ºC. After a period of two months, the eggs were thawed and fertilized with her partner's sperm through in-vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI), and the resulting embryos implanted in her uterus.

"The patient went through an uncomplicated full-term pregnancy and straightforward delivery," says Dr. William Buckett, the MUHC physician who looked after the mother during the pregnancy. The parents, who requested anonymity, described the procedure as easy and uncomplicated. The father stated: "Words cannot describe the event--I was standing in the delivery ward and I was helping my beautiful partner when she gave birth to this beautiful baby. I wish to take this opportunity to thank the MUHC staff, and especially the staff of the Reproductive Centre."

The McGill Reproductive Centre of t he MUHC is pioneering a revolutionary new freezing technique, which has dramatically increased egg survival rate. Human eggs are very fragile and have high water content. Conventional methods of freezing have been relatively unsuccessful because they allow the formation of ice crystals, damaging the cells and rendering the egg unusable. This problem has now been resolved by a new method of rapid freezing called vitrification developed at McGill by Dr. Ri-Cheng Chian, Scientific Director of the McGill Reproductive Centre at the MUHC and Dr. Tan. Each egg extracted from the ovaries of the patient is drawn into a protective device, invented by Drs. Chian and Tan, called a "Cryoleaf", and then placed in a special vitrification solution. The eggs undergo super-rapid cooling at a rate of more than 20,000ºC per minute, which prevents ice crystal formation and increases egg survival to approximately 90%. The frozen eggs can then be safely stored in the Cryoleaf until it is ready for use, at which point it is carefully thawed, then fertilized.

To date, 15 patients at the McGill Reproductive Centre have had embryo transfer produced from vitrified eggs, resulting in 7 pregnancies including this livebirth. "The results are particularly encouraging because this success rate is comparable to regular IVF cycles with ICSI using fresh eggs in many IVF centres," says Dr. Tan.

Egg freezing is useful for a number of reasons. "The process enables young women diagnosed with cancer to preserve their fertility before undergoing chemotherapy and radiotherapy, which can cause infertility and premature menopause," says Dr. Lucy Gilbert, Director of Gynecological Oncology at the MUHC. Over the past two years, 16 cancer patients have had their eggs frozen at the MUHC. "Egg freezing also allows young women who wish to delay childbearing to do so safely," notes Dr. Tan. After 30 years of age, a woman's fertility declines and the rate of spontaneous abortion increases significantly . The risks of chromosomal abnormalities, such as Down's syndrome, are also higher in babies produced by older women. Finally, current egg donor programs require matching the menstrual cycle of egg recipients; this problem can be eliminated with egg freezing.


'"/>

Source:McGill University


Related biology news :

1. Timing is everything: First step in protein building revealed
2. Emory Eye Center Implants Its First Retinal Chips In Patients With Retinitis Pigmentosa
3. First atlas of key brain genes could speed research on cancer, neurological diseases
4. First-ever Compounds To Target Only Metastatic Cells Are Highly Effective Against Breast, Prostate, And Colon Cancers
5. NYCs First Rapid HIV Drug-resistant AIDS Case Prompts Call to Step Up HIV Prevention
6. First real-time view of developing neurons reveals surprises, say Stanford researchers
7. Breast-Cancer Risk Linked to Exposure to Traffic Emissions at Menarche, First Birth
8. Mayo Clinic Researchers Create Obedient Virus; First Step To Use Measles Virus Against Cancer
9. Human Cells Filmed Instantly Messaging for First Time
10. First North American Encapsulated Islet Transplant without Long-term Immune Suppression into a Patient with Type 1 Diabetes
11. First technology to remove prions that cause vCJD from blood launched
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/20/2016)... LONDON , Dec. 20, 2016 ... car sharing, rental and leasing is stoking significant ... of radio frequency technology, Bluetooth low energy (BLE), ... emerge as the next wave of wireless technologies ... vehicle access system to advanced access systems opens ...
(Date:12/19/2016)... y TORONTO , 19 de diciembre de 2016 ... Inc. que permitirá el desarrollo acelerado de MSC-1, un anticuerpo humanizado ... tipos de tumor en 2017, con múltiples sitios previstos a lo ... ... objetivo en el factor inhibidor de leucemia (LIF), una citoquina pleiotrópica ...
(Date:12/16/2016)... , Dec 16, 2016 Research and ... System Market - Global Forecast to 2021" report to their ... The ... to grow at a CAGR of 14.06% from 2016 to 2021. ... and is projected to reach 854.8 Million by 2021. The growth ...
Breaking Biology News(10 mins):
(Date:1/18/2017)... OR (PRWEB) , ... January 18, 2017 , ... ... that provide essential device-to-computer interconnect using USB or PCI Express, announced the ZEM5310 ... Cyclone V E FPGA into a compact business-card sized form factor suitable for ...
(Date:1/18/2017)... Jan. 18, 2017 Applied BioMath ( ... to drug research and development, today announced that ... and CEO of Applied BioMath, will present at ... Modeling (BAGIM) Meeting on Thursday January 19, 2017 ... , MA.   Dr. Burke,s talk "Quantitative Modeling ...
(Date:1/18/2017)... ... January 18, 2017 , ... Total ... successfully implanted SpineFrontier’s A-CIFT™ Solofuse-P™. The operation took place on Wednesday, January 11, ... The procedure was an anterior cervical discectomy and fusion on a 42 year ...
(Date:1/18/2017)... ... January 18, 2017 , ... MYOLYN, ... that it has submitted a 510(k) to the FDA, requesting clearance of the ... functional electrical stimulation (FES) technology. , The submission marks a major milestone ...
Breaking Biology Technology: