Navigation Links
First-degree fetal heart block may be reversible

There is an increased risk of fetal heart problems when mothers carry particular antibodies associated with rheumatic diseases, according to an abstract presented by Yale School of Medicine researchers at the Society for Maternal-Fetal Medicine Conference February 9 in San Francisco.

Congenital heart block (CHB) is present at or before birth and impairs the heart's electrical signaling from the upper to the lower chambers. CHB carries a 20 percent death rate and nearly all survivors require pacemakers. Joshua Copel, M.D., professor in the Department of Obstetrics, Gynecology & Reproductive Sciences at Yale helped conduct the PR Interval and Dexamethasone Evaluation (PRIDE) study with a team of other researchers to evaluate an early marker of cardiac injury before there is permanent scarring.

The PRIDE group conducted a longitudinal (observational) study following over 100 women with the anti-Ro and anti-La antibodies to determine if there were early signs of fetal heart problems. They also explored whether early treatment would reverse the problems.

The team found that while first-degree fetal heart block may be reversible with the steroid drug dexamethasone, the condition could advance within as little as one week to a third-degree block, which is irreversible even with further intervention.

"Given the high recurrence rate we confirmed in this study, close monitoring and the earliest possible marker is necessary," said Copel, who plans trials of other possible treatments. "Advanced block and permanent heart damage can occur within one week of a normal echocardiogram, even a weekly evaluation may not be sufficient to detect early onset of disease."
'"/>

Source:Yale University


Page: 1

Related biology news :

1. Ultrasounds show mothers drinking shrinks fetal brain
2. Technology for monitoring fetal oxygen during labor offers no apparent benefit
3. UCSD team discovers specialized, rare heart stem cells in newborns
4. Single stem cells from bone heal a broken heart
5. Python a hearty eater
6. Columbia study shows widely used artery clearing device does not help patients during heart attack
7. Researchers reveal secret of key protein in brain and heart function
8. Stem cell therapy successfully treats heart attack in animals
9. New defibrillator signals doctor of patients irregular heartbeat or device malfunction
10. Survival of heart patients on beta-blockers varies greatly with genetic variation
11. Chemical band-aid prevents heart failure in mice with muscular dystrophy
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: First degree fetal heart block may reversible

(Date:4/2/2015)... At its 2015 ACMG Annual Clinical Genetics ... the American College of Medical Genetics and Genomics (ACMG) ... Board.  Members of the ACMG Board of Directors serve ... advancing its policies and programs. ACMG is the national ... an eventful time in medical genetics and genomics.  We ...
(Date:3/31/2015)... 31, 2015  Elephant Talk Communications Corp. (NYSE MKT: ... of Software Defined Network Architecture (ET Software DNA® 2.0) ... of approximately $20.4 million for the year ended December ... for the year ended December 31, 2013. ... had completed its multi-year transition away from its legacy ...
(Date:3/24/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/kvdtcw/face_and_voice ) has ... Global Strategic Business Report" report to their offering. ... in US$ Thousands by the following Segments: Face Biometrics, and Voice ... Canada , Japan , ... East & Africa , and ...
Breaking Biology News(10 mins):American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 2American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 3American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 4American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 5American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 6American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 7American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 8Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 2Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 3Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 4Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 5Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 6Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 2Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 3Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 4Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 5Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 6
... a new and potentially important mechanism by which chemical ... clouds that reflect sunlight away from our planet. ... and the biosphere grew out of efforts to explain ... Southern Ocean where a large bloom of phytoplankton was ...
... that the Chlamydia bacterium, which causes a sexually transmitted ... shared evolutionary heritage, which is not found in most ... of an effective cure for Chlamydia infections. , "The ... been proposed by others," said Thomas Leustek," a professor ...
... broadens our understanding of primate cooperation, researchers have ... and draw on an evolutionarily old principle--shared with ... that produces flexible, adaptive, and cooperative responses by ... is reported by Kimberley Hockings and James Anderson ...
Cached Biology News:Researchers link ocean organisms with increased cloud cover and potential climate change 2Researchers link ocean organisms with increased cloud cover and potential climate change 3Researchers link ocean organisms with increased cloud cover and potential climate change 4Common ancestry of bacterium and plants could be key to an effective new treatment for chlamydia 2Common ancestry of bacterium and plants could be key to an effective new treatment for chlamydia 3Road-crossing in chimpanzees: A risky business 2
(Date:4/16/2015)... , April 16, 2015  In recognition of World Hemophilia ... hemophilia advocacy groups to illuminate more than 15 prominent landmarks ... Boston,s Zakim Bridge and Prudential Tower, ... Orleans, Mercedes-Benz Superdome and Denver,s ... the evening of April 17, and coincide with hemophilia community ...
(Date:4/16/2015)... April 16, 2015 /CNW/ - Bioenterprise Corporation is pleased to ... in Charlottetown , PEI.  Bioenterprise has ... Island ADAPT Council for the commercialization of agricultural technologies ... working with PEI ADAPT.  They have been at the ... a decade," explains Dave Smardon , President & ...
(Date:4/16/2015)... SAN DIEGO , April 16, 2015 /PRNewswire/ ... and development of therapeutic antibodies, today announced ... (IL-36R) antibody program into IND-enabling studies. The ... a novel treatment for generalized pustular psoriasis ... high unmet medical need. ANB019 is wholly owned ...
(Date:4/16/2015)... Mass. , April 16, 2015  EMD ... Merck KGaA, Darmstadt, Germany , ... Vice President, Head of Global Clinical Development.  Dr. ... expertise, including experience in Oncology and Immunology. She ... ability, having served as a Vice President in ...
Breaking Biology Technology:Biogen Shines A Light On Hemophilia Community By Illuminating U.S. Landmarks Red On World Hemophlia Day 2Biogen Shines A Light On Hemophilia Community By Illuminating U.S. Landmarks Red On World Hemophlia Day 3Biogen Shines A Light On Hemophilia Community By Illuminating U.S. Landmarks Red On World Hemophlia Day 4Bioenterprise Corporation Expands into the Maritimes 2AnaptysBio Advances First-In-Class Anti-IL-36 Receptor Antibody Program To Treat Orphan Inflammatory Disease 2Alise Reicin Joins the Biopharmaceutical Business of Merck KGaA, Darmstadt, Germany as Head of Global Clinical Development 2Alise Reicin Joins the Biopharmaceutical Business of Merck KGaA, Darmstadt, Germany as Head of Global Clinical Development 3
... Produces Isobutene From... -- EVRY, France, October 6, 2010 ... ... ... first_result; // Results are keyed by longUrl, so we need to grab the first one. for (var ...
... 6, 2010 ... ... var shortURL = ... so we need to grab the first one. for (var r in data.results) { first_result = data.results[r]; ...
... Knowing how to build nanosized assemblies of polymers (long ... range of industrial processes, from the production of nanofibers, ... nanoscale circuits and devices. A recent paper in ... polymers in specially engineered confined spaces, opening the door ...
Cached Biology Technology:Global Bioenergies Succeeds in Creating a Bacterial Prototype That Produces Isobutene From Glucose 2Global Bioenergies Succeeds in Creating a Bacterial Prototype That Produces Isobutene From Glucose 3Global Bioenergies Succeeds in Creating a Bacterial Prototype That Produces Isobutene From Glucose 4Global Bioenergies Succeeds in Creating a Bacterial Prototype That Produces Isobutene From Glucose 5Global Bioenergies Succeeds in Creating a Bacterial Prototype That Produces Isobutene From Glucose 6Global Bioenergies Succeeds in Creating a Bacterial Prototype That Produces Isobutene From Glucose 7Elsevier Introduces Article-Based Publishing to Increase Publication Speed 2Elsevier Introduces Article-Based Publishing to Increase Publication Speed 3Elsevier Introduces Article-Based Publishing to Increase Publication Speed 4Elsevier Introduces Article-Based Publishing to Increase Publication Speed 5Elsevier Introduces Article-Based Publishing to Increase Publication Speed 6Elsevier Introduces Article-Based Publishing to Increase Publication Speed 7Elsevier Introduces Article-Based Publishing to Increase Publication Speed 8Building a smaller, lighter future: Understanding polymer behaviors below 1 nanometer 2
...
Mouse monoclonal [H4B4] to LAMP2 - Lysosome Marker (Phycoerythrin) ( Abpromise for all tested applications). entrezGeneID: 3920 SwissProtID: P13473...
Mouse monoclonal [IA-C6] to MHC Class II I Ab + Ad (FITC) ( Abpromise for all tested applications). Antigen: Tissue / cell preparation of Purified Mouse lymph node B cells...
...
Biology Products: