Navigation Links
First-degree fetal heart block may be reversible

There is an increased risk of fetal heart problems when mothers carry particular antibodies associated with rheumatic diseases, according to an abstract presented by Yale School of Medicine researchers at the Society for Maternal-Fetal Medicine Conference February 9 in San Francisco.

Congenital heart block (CHB) is present at or before birth and impairs the heart's electrical signaling from the upper to the lower chambers. CHB carries a 20 percent death rate and nearly all survivors require pacemakers. Joshua Copel, M.D., professor in the Department of Obstetrics, Gynecology & Reproductive Sciences at Yale helped conduct the PR Interval and Dexamethasone Evaluation (PRIDE) study with a team of other researchers to evaluate an early marker of cardiac injury before there is permanent scarring.

The PRIDE group conducted a longitudinal (observational) study following over 100 women with the anti-Ro and anti-La antibodies to determine if there were early signs of fetal heart problems. They also explored whether early treatment would reverse the problems.

The team found that while first-degree fetal heart block may be reversible with the steroid drug dexamethasone, the condition could advance within as little as one week to a third-degree block, which is irreversible even with further intervention.

"Given the high recurrence rate we confirmed in this study, close monitoring and the earliest possible marker is necessary," said Copel, who plans trials of other possible treatments. "Advanced block and permanent heart damage can occur within one week of a normal echocardiogram, even a weekly evaluation may not be sufficient to detect early onset of disease."
'"/>

Source:Yale University


Page: 1

Related biology news :

1. Ultrasounds show mothers drinking shrinks fetal brain
2. Technology for monitoring fetal oxygen during labor offers no apparent benefit
3. UCSD team discovers specialized, rare heart stem cells in newborns
4. Single stem cells from bone heal a broken heart
5. Python a hearty eater
6. Columbia study shows widely used artery clearing device does not help patients during heart attack
7. Researchers reveal secret of key protein in brain and heart function
8. Stem cell therapy successfully treats heart attack in animals
9. New defibrillator signals doctor of patients irregular heartbeat or device malfunction
10. Survival of heart patients on beta-blockers varies greatly with genetic variation
11. Chemical band-aid prevents heart failure in mice with muscular dystrophy
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: First degree fetal heart block may reversible

(Date:7/11/2014)... including scientists from the Max Planck Institute for Medical ... step in understanding photosynthesis, the process by which the ... its atmosphere and which is therefore crucial for all ... researchers report the first direct visualization of a crucial ... which a specific protein complex, photosystem II, splits water ...
(Date:7/11/2014)... 11, 2014 Researchers have pioneered a revolutionary ... new technology, called Virtual Finger, allows scientists to ... neurons and synapses using the flat surface of ... 3D imaging studies orders of magnitude more efficient, ... level across many areas of experimental biology. The ...
(Date:7/11/2014)... has demonstrated that transplantation of mesenchymal stem cells can ... mouse models of Alzheimer,s disease (AD) and improve tissue ... Few studies are reported on the therapeutic effect of ... and on the effect on oxidative injury and neurogenesis ... and her team, School of Life Sciences, Tsinghua University, ...
Breaking Biology News(10 mins):A first direct glimpse of photosynthesis in action 2Virtual finger enables scientists to navigate and analyze complex 3D images 2
... ill, or suffered an injury, you,ve watched gloomily as your ... about as common to the human condition as breathing. ... causes skeletal muscles to atrophy. They know proteins are responsible, ... key actors from the poseurs is tricky. In a ...
... the atmosphere are rising; the average temperatures of the ... these changes. The transitional zones between shallow shelf seas ... huge amount of methane hydrates in the sea bed. ... and under high pressure. When the water temperature directly ...
... linked to type 2 diabetes have been discovered by an ... The study provides a fuller picture of the genetics ... patterns emerging. The international team, led by researchers ... and MIT, and the University of Michigan, Ann Arbor, used ...
Cached Biology News:Researchers identify key culprit causing muscle atrophy 2Researchers identify key culprit causing muscle atrophy 3Are methane hydrates dissolving? 210 new diabetes gene links offer picture of biology underlying disease 210 new diabetes gene links offer picture of biology underlying disease 3
(Date:7/10/2014)... Using microscopic polymer light resonators that expand in ... Quantum Photonics Laboratory have developed new optical sensors ... Optical sensors are ideal for detecting trace gas ... lightweight nature, and immunity to electromagnetic interference. , ... before, the MIT team conceived an extremely sensitive, ...
(Date:7/10/2014)... Columbia researchers have observed the fractional quantum Hall effect ... of matter can be tuned by an electric field. ... occur when electrons confined to thin sheets are exposed ... collective behavior where thousands of individual electrons behave as ... this effect is well established, many details of this ...
(Date:7/10/2014)... 1960s, theatergoers have shelled out for crude 3-D ... their viewing experience. These basic devices, used to ... reality, may soon be rendered obsolete with the ... Aviv University researchers. , TAU doctoral students Yuval ... highly efficient holography based on nanoantennas that could ...
(Date:1/15/2014)... akin to assembling a club sandwich at the ... researchers have succeeded in crafting a uniform, multi-walled ... foam commonly used in upholstered furniture and other ... polyurethane foam was reduced 35 percent compared with ...
Breaking Biology Technology:Swell new sensors 2Columbia researchers observe tunable quantum behavior in bilayer graphene 2Columbia researchers observe tunable quantum behavior in bilayer graphene 3Projecting a 3-dimensional future 2Projecting a 3-dimensional future 3Layered security: Carbon nanotubes promise improved flame-resistant coating 2
... PHOENIX, Nov. 12 Arizona Heart Innovative Technologies,LLC (AHIT) ... endovascular,use to a publicly traded medical device company. "This ... the past ten months. We,continue to demonstrate our ability ... community to commercially viable products for medical,device companies. This ...
... Zentaris Inc.,(NASDAQ: AEZS , TSX: AEZ), a ... will announce its third quarter 2008,financial and operating ... a.m.,The Company will host a conference call and ... at 10:00 a.m., Eastern Time., Participants may ...
... Novavax, Inc.,(Nasdaq: NVAX ) a clinical-stage vaccine ... Executive Officer, will be presenting at,the Lazard Capital Markets ... 19, 2008 at the St. Regis Hotel, New York ... strategy, research and,development progress. A link to the live ...
Cached Biology Technology:Arizona Heart Innovative Technologies Licenses New Endovascular Device 2
...
... PlusOne Silver Staining Kit, Protein, 1. ... and Dernick (1), the kit gives ... electrophoresis systems.Silver Staining Kit, Protein provides ... proteins in polyacrylamide gels in less ...
Mouse monoclonal [IFR0104] to Salmonella enteriditis ( Abpromise for all tested applications)....
Cyno macaque plasma and serum - various quantities available...
Biology Products: