Navigation Links
First big influenza genome study reveals flu evolution

Which flu did you get? TIGR scientists survey five New York flu seasons

On the eve of the 2005-06 flu season, scientists at The Institute for Genomic Research (TIGR) have captured influenza evolution in action. In a study published in this week's journal Nature, the researchers report the first large-scale project to sequence the influenza virus. The study offers a unique snapshot of the rapidly evolving flu virus in a human population--and a new strategy for surveillance.

In the study, TIGR scientists and their colleagues sequenced 209 complete genomes of the human influenza A virus. The genomes represent virus samples, or isolates, taken from patients who visited county clinics across New York over the past five flu seasons, from 1999-2004. Almost all the influenza genomes represent the H3N2 strain, which predominated during these flu seasons. Comparing these genomes, the researchers tracked the changing virus as it moved across the region.

"This study demonstrates that genomics can help us better track the flu virus and develop more effective vaccines," remarks first author Elodie Ghedin, who heads TIGR's viral genomics lab. "This is perhaps the most detailed snapshot scientists have gotten of flu's movement through communities."

Across New York State, the researchers documented at least three distinct subpopulations (variants) of the H3N2 influenza virus over the five-year study period. In some of the flu seasons studied, these variants circulated simultaneously. That means New Yorkers weren't all catching the same flu, but rather slightly different versions of the virus. Even within this relatively small geographic region, Ghedin says, the dynamic influenza virus showed striking diversity, with variants frequently swapping genetic material.

In fact, the researchers report, one such event explains why the 2003-04 flu vaccine offered less protection than usual.

Every flu season, a global network of scientist
'"/>

Source:The Institute for Genomic Research


Page: 1 2 3 4

Related biology news :

1. Timing is everything: First step in protein building revealed
2. Emory Eye Center Implants Its First Retinal Chips In Patients With Retinitis Pigmentosa
3. First atlas of key brain genes could speed research on cancer, neurological diseases
4. First-ever Compounds To Target Only Metastatic Cells Are Highly Effective Against Breast, Prostate, And Colon Cancers
5. NYCs First Rapid HIV Drug-resistant AIDS Case Prompts Call to Step Up HIV Prevention
6. First real-time view of developing neurons reveals surprises, say Stanford researchers
7. Breast-Cancer Risk Linked to Exposure to Traffic Emissions at Menarche, First Birth
8. Mayo Clinic Researchers Create Obedient Virus; First Step To Use Measles Virus Against Cancer
9. First frozen egg baby born in Canada
10. Human Cells Filmed Instantly Messaging for First Time
11. First North American Encapsulated Islet Transplant without Long-term Immune Suppression into a Patient with Type 1 Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: First big influenza genome study reveals flu evolution

(Date:7/8/2015)... LAKES , N.J. and NEW YORK ... Company) and Guidepoint today announced BD ... start-up healthcare companies with free access to Guidepoint,s expert ... several start-ups that are developing cutting-edge technologies to improve ... a dedicated Guidepoint research manager, each start-up entrepreneur will ...
(Date:7/7/2015)... Calif. , July 7, 2015  Based ... market, Frost & Sullivan recognizes Credence ID, LLC ... Entrepreneurial Company of the Year Award. Credence ... to aid in its mission of offering enrollment ... populations globally. As Credence ID was formed by ...
(Date:7/2/2015)... Fingerprint Cards has received an order for its ... distributor World Peace Industrial Group (WPI), part of WPG Holdings. ... . Deliveries are planned to take place during Q3 ... manufacturers in Asia . The order value ... of approximately 2,200 MSEK for 2015. Jörgen Lantto, ...
Breaking Biology News(10 mins):BD and Guidepoint Team to Connect Healthcare Start-up Companies With Business and Scientific Experts 2BD and Guidepoint Team to Connect Healthcare Start-up Companies With Business and Scientific Experts 3Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 2Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 3Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 4Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 5FPC Receives Order for Touch Fingerprint Sensors of 268 MSEK 2
... Conservancy (WPC) scientists have discovered a plant in Erie County ... dwarf scouring rush, was identified with the aid of a ... Girard. Dwarf scouring rush is known to exist in ... not been identified in Pennsylvania until this discovery. WPC scientists ...
... The Potato Genome Sequencing Consortium (PGSC), an international ... countries, has released a draft sequence of the potato ... Richard Veilleux, professor of horticulture in the College ... a unique phureja type of potato variety that accelerated ...
... Investigators at Burnham Institute for Medical Research (Burnham), University ... Research Institute (TSRI), Genomics Institute of the Novartis Research ... model, including three dimensional protein structures, of the central ... ( T. maritima ). This is the first time ...
Cached Biology News:Erie County home to plant never before recorded in Pa. 2Draft potato genome based on unique potato variety 2Comprehensive understanding of bacteria could lead to new insights into many organisms 2
(Date:7/29/2015)... 30, 2015 Sanofi, a ... the second quarter of 2015. CEO Olivier ... its performance in different businesses. Watch ... http://www.eurobusinessmedia.com/ceo-direct/sanofi/sanofi-h1-2015-results-interview-with-ceo-olivier-brandicourt?utm_source=ceo-direct&utm_medium=wire Topics covered in the ... - Performance drivers - Diabetes ...
(Date:7/29/2015)... , July 29, 2015 /PRNewswire/ - BioAmber Inc. (NYSE: ... , the Company,s Chief Financial Officer has resigned.  The ... Chief Financial Officer who retired in December 2014, as ... for a permanent successor.     Andy Ashworth ... Laurin and ensure a smooth transition.  Andy was the ...
(Date:7/29/2015)... Wis. (PRWEB) , ... July 29, 2015 , ... ... identification solutions, today announced its GHS Label Guide . To align chemical ... System (GHS), this guide includes explanations of label components, an example of an ...
(Date:7/29/2015)... ... ... The third Medical Innovation Impact Index (MI3) Alert considers FDA processes for the ... system received a score of 0 (range -10 to +10) for its impact on ... Dickinson University’s ( FDU ) Rothman Institute of Innovation and Entrepreneurship. Several changes to ...
Breaking Biology Technology:BioAmber Announces Change in Chief Financial Officer 2BioAmber Announces Change in Chief Financial Officer 3Brady Announces a New GHS Label Guide 2Third Medical Innovation Impact Index Issued by Fairleigh Dickinson University’s Initiative for Patient-Centered Innovation (iPCI) 2Third Medical Innovation Impact Index Issued by Fairleigh Dickinson University’s Initiative for Patient-Centered Innovation (iPCI) 3
... Mich., April 15 GeneGo, Inc., the leading,systems ... Science Institute has joined the MetaMiner Cardiac,Consortium. The ... first systems,biology and pathway analysis platform for cardiovascular ... on deliverables that will include,disease specific pathway maps ...
... April 15 WallSt.net,s 3-Minute Press Show is,a ... Tolentino., Shows air Monday through Friday on:, ... Show features in-depth interviews with,public company executives on ... is designed to provide viewers with insight into ...
... /PRNewswire-FirstCall/ - AEterna Zentaris Inc.,(NASDAQ: AEZS ; ... therapy and oncology, today reported the completion of ... its Phase 3 program,in benign prostatic hyperplasia (BPH), ... product candidate, cetrorelix. The study,involves approximately 600 patients ...
Cached Biology Technology:The Scripps Translational Science Institute Joins The MetaMiner Cardiac Consortium 2Featured Stocks on Today's Edition of WallSt.net's 3-Minute Press Show: NPHC, PECD, PNRR 2Featured Stocks on Today's Edition of WallSt.net's 3-Minute Press Show: NPHC, PECD, PNRR 3AEterna Zentaris Completes Patient Recruitment for First Phase 3 Efficacy Trial with Cetrorelix in Benign Prostatic Hyperplasia 2AEterna Zentaris Completes Patient Recruitment for First Phase 3 Efficacy Trial with Cetrorelix in Benign Prostatic Hyperplasia 3AEterna Zentaris Completes Patient Recruitment for First Phase 3 Efficacy Trial with Cetrorelix in Benign Prostatic Hyperplasia 4
Best pricing for 100mg-1.0g scales. Phosphopeptides are our specialty....
... The ProteomeLab PF 2D is an automated, ... complex protein mixtures. Part of Beckman ... 2D produces results in just hours. ... proteins present in cell lysates, addressing a ...
... Panels were designed for full-length gene cloning ... to identify the desired cDNA clone. The ... 96-well "Master Plate," where each well contains ... the positive well(s) by gel electrophoresis of ...
... 295 ex can measure three fluorescence lifetimespicoseconds ... a few minutes. To match the absorption ... tryptophan, the Protein 295 exs excitation source ... emitting 295 nm. Fluorescence of tryptophan is ...
Biology Products: