Navigation Links
First Quantum Grant to fund stem cell repair of damage from stroke

The National Institutes of Health has named researchers at Baylor College of Medicine (BCM) and Rice University in Houston as the first and only recipients of the inaugural Quantum Grant for their international research initiative to regenerate damaged brain cells and blood vessels for the treatment of stroke.

The three-year, $2.9 million grant, funded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB), part of the NIH, will support research on neuro-vascular regeneration, which will make new brain tissues in the laboratory. The new brain tissue is planned to have its own blood supply to allow it to be placed into the damaged brains of stroke patients where it will provide a source of neural and vascular cells that will continue to develop and differentiate, repairing the injured tissue in the process.

"This project represents an integrated effort among leading scientists who have jointly authored numerous publications, mentored students and postdoctoral fellows, as well as collaborated on Bioengineering Research Partnership grants," said Jennifer West, who is leading the project's efforts at Rice. West is the Isabel C. Cameron Professor of Bioengineering and director of Rice's Institute of Biosciences and Bioengineering.

The newly created NIBIB Quantum Grants Program supports researchers in the development of innovative biomedical technologies in hopes of making a significant impact in the prevention, diagnosis and treatment of disease. Funding was awarded to only one grant application out of more than 100 submitted.

Karen Hirschi, deputy director of the Stem Cell and Regenerative Medicine Center within the Center for Cell and Gene Therapy at BCM, is the principal investigator for the "Neuro-Vascular Regeneration" project, which will be conducted in conjunction with an interdisciplinary team of researchers at Rice, the National Institute for Medical Research in London, and King's College in London.

"Each member of our team has made significant contributions to the advancement of their respective fields of research and will now be able to devote substantial efforts to integrating their work and developing methods of using neuro-vascular regeneration to help stroke victims," Hirschi said.

The project team members come from diverse and complementary areas of expertise in developmental neurobiology and vascular biology, stem cell biology, genetics, biomedical imaging, tissue engineering, and clinical cellular therapies. Spanning fields of science that include cell and molecular biology, animal models of disease, and hopefully human clinical trials, the "Neuro-Vascular Regeneration" project falls in line with the NIH roadmap for the development of multi-disciplinary and translational science.

The BCM team also includes project co-developer Mary Dickinson, assistant professor of molecular physiology and biophysics at BCM; Dr. Thomas Zwaka, assistant professor of molecular and cellular biology in the Center for Cell and Gene Therapy at BCM; and Malcolm Brenner, professor of medicine and pediatrics and director of the Center for Cell and Gene Therapy at BCM.

Robin Lovell-Badge, head of the division of developmental genetics at the National Institute for Medical Research in London, serves as co-principal investigator of the project. Other investigators in London include Jack Price and Mike Modo, both of the Centre for the Cellular Basis of Behaviour at the Institute of Psychiatry at King's College.


'"/>

Source:Rice University


Related biology news :

1. Timing is everything: First step in protein building revealed
2. Emory Eye Center Implants Its First Retinal Chips In Patients With Retinitis Pigmentosa
3. First atlas of key brain genes could speed research on cancer, neurological diseases
4. First-ever Compounds To Target Only Metastatic Cells Are Highly Effective Against Breast, Prostate, And Colon Cancers
5. NYCs First Rapid HIV Drug-resistant AIDS Case Prompts Call to Step Up HIV Prevention
6. First real-time view of developing neurons reveals surprises, say Stanford researchers
7. Breast-Cancer Risk Linked to Exposure to Traffic Emissions at Menarche, First Birth
8. Mayo Clinic Researchers Create Obedient Virus; First Step To Use Measles Virus Against Cancer
9. First frozen egg baby born in Canada
10. Human Cells Filmed Instantly Messaging for First Time
11. First North American Encapsulated Islet Transplant without Long-term Immune Suppression into a Patient with Type 1 Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/1/2016)... Feb. 1, 2016  Wocket® smart wallet ( www.wocketwallet.com ) announces the ... Joey Fatone . Las Vegas , where ... --> Las Vegas , where Joey appeared at ... The new video ad was filmed at the Consumer Electronics Show (CES2016) ... Wocket booth to meet and greet fans. --> ...
(Date:1/25/2016)... , Jan. 25, 2016   Unisys Corporation (NYSE: ... at John F. Kennedy (JFK) International Airport, New York ... (CBP) identify imposters attempting to enter the United ... belong to them. pilot testing of the system ... at three terminals at JFK during January 2016. --> ...
(Date:1/22/2016)... http://www.researchandmarkets.com/research/p74whf/global_biometrics ) ... "Global Biometrics Market in Retail Sector 2016-2020" ... --> http://www.researchandmarkets.com/research/p74whf/global_biometrics ) has announced the ... in Retail Sector 2016-2020" report to ... and Markets ( http://www.researchandmarkets.com/research/p74whf/global_biometrics ) has announced ...
Breaking Biology News(10 mins):
(Date:2/11/2016)... and GERMANTOWN, Maryland , February 11, ... Standard: QIA) today announced the introduction of more than ... profiling, expanding QIAGEN,s portfolio of Sample to Insight solutions ... select from over 20,000 human genes and lncRNA to ... cellular phenotypes and disease processes. --> QGEN ...
(Date:2/11/2016)... Feb. 11, 2016  Spectra BioPharma Selling Solutions (Spectra) ... provides biopharma companies the experience, expertise, operational delivery ... outsourced sales teams. Created in concert with industry ... the strategic and tactical needs of its clients ... through both personal and non-personal promotion. ...
(Date:2/11/2016)... ... February 11, 2016 , ... ... cutting-edge information focused on the development and manufacture of biopharmaceuticals and therapeutics, ... sponsor of the 2016 BioProcess International Awards – Recognizing Excellence in the ...
(Date:2/11/2016)... 2016 --> ... (OTCQB: PSID), a life sciences company focused on ... subsidiary, which markets the Caregiver® FDA-cleared non-contact thermometer, ... January 2016, including entering into agreements with five ... growth, and establishing several near-term pipeline opportunities. ...
Breaking Biology Technology: