Navigation Links
First Quantum Grant to fund stem cell repair of damage from stroke

The National Institutes of Health has named researchers at Baylor College of Medicine (BCM) and Rice University in Houston as the first and only recipients of the inaugural Quantum Grant for their international research initiative to regenerate damaged brain cells and blood vessels for the treatment of stroke.

The three-year, $2.9 million grant, funded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB), part of the NIH, will support research on neuro-vascular regeneration, which will make new brain tissues in the laboratory. The new brain tissue is planned to have its own blood supply to allow it to be placed into the damaged brains of stroke patients where it will provide a source of neural and vascular cells that will continue to develop and differentiate, repairing the injured tissue in the process.

"This project represents an integrated effort among leading scientists who have jointly authored numerous publications, mentored students and postdoctoral fellows, as well as collaborated on Bioengineering Research Partnership grants," said Jennifer West, who is leading the project's efforts at Rice. West is the Isabel C. Cameron Professor of Bioengineering and director of Rice's Institute of Biosciences and Bioengineering.

The newly created NIBIB Quantum Grants Program supports researchers in the development of innovative biomedical technologies in hopes of making a significant impact in the prevention, diagnosis and treatment of disease. Funding was awarded to only one grant application out of more than 100 submitted.

Karen Hirschi, deputy director of the Stem Cell and Regenerative Medicine Center within the Center for Cell and Gene Therapy at BCM, is the principal investigator for the "Neuro-Vascular Regeneration" project, which will be conducted in conjunction with an interdisciplinary team of researchers at Rice, the National Institute for Medical Research in London, and King's College in London.

"Each member of our team has made significant contributions to the advancement of their respective fields of research and will now be able to devote substantial efforts to integrating their work and developing methods of using neuro-vascular regeneration to help stroke victims," Hirschi said.

The project team members come from diverse and complementary areas of expertise in developmental neurobiology and vascular biology, stem cell biology, genetics, biomedical imaging, tissue engineering, and clinical cellular therapies. Spanning fields of science that include cell and molecular biology, animal models of disease, and hopefully human clinical trials, the "Neuro-Vascular Regeneration" project falls in line with the NIH roadmap for the development of multi-disciplinary and translational science.

The BCM team also includes project co-developer Mary Dickinson, assistant professor of molecular physiology and biophysics at BCM; Dr. Thomas Zwaka, assistant professor of molecular and cellular biology in the Center for Cell and Gene Therapy at BCM; and Malcolm Brenner, professor of medicine and pediatrics and director of the Center for Cell and Gene Therapy at BCM.

Robin Lovell-Badge, head of the division of developmental genetics at the National Institute for Medical Research in London, serves as co-principal investigator of the project. Other investigators in London include Jack Price and Mike Modo, both of the Centre for the Cellular Basis of Behaviour at the Institute of Psychiatry at King's College.


'"/>

Source:Rice University


Related biology news :

1. Timing is everything: First step in protein building revealed
2. Emory Eye Center Implants Its First Retinal Chips In Patients With Retinitis Pigmentosa
3. First atlas of key brain genes could speed research on cancer, neurological diseases
4. First-ever Compounds To Target Only Metastatic Cells Are Highly Effective Against Breast, Prostate, And Colon Cancers
5. NYCs First Rapid HIV Drug-resistant AIDS Case Prompts Call to Step Up HIV Prevention
6. First real-time view of developing neurons reveals surprises, say Stanford researchers
7. Breast-Cancer Risk Linked to Exposure to Traffic Emissions at Menarche, First Birth
8. Mayo Clinic Researchers Create Obedient Virus; First Step To Use Measles Virus Against Cancer
9. First frozen egg baby born in Canada
10. Human Cells Filmed Instantly Messaging for First Time
11. First North American Encapsulated Islet Transplant without Long-term Immune Suppression into a Patient with Type 1 Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/2/2017)... Australia , March 2, 2017 Australian ... Ltd (ASX: CYP), has signed an agreement with ... from the Monash Biomedicine Discovery Institute and Department of ... to conduct a further preclinical study to support the ... treatment of asthma.  Asthma is a ...
(Date:2/28/2017)... 2017 News solutions for biometrics, bag drop ... ... 14 to 16 March, Materna will present its complete end-to-end ... travel is a real benefit for passengers. To accelerate the ... passenger touch point solutions to take passengers through the complete ...
(Date:2/26/2017)... 2017  Securus Technologies, a leading provider of ... safety, investigation, corrections and monitoring, announces the appointment ... "Too often, too many offenders return to ... are trying to tackle this ongoing problem and ... family members. While significant steps are underway, Securus continues ...
Breaking Biology News(10 mins):
(Date:3/23/2017)... NetworkNewsWire Editorial Coverage  ... Cancer remains one of the world,s ... systems, in terms of costs and resources. However, as the ... of innovative and efficient therapies that demonstrate higher chances of ... cancer treatments, a growing number of patients receiving immuno-oncology therapies ...
(Date:3/23/2017)... VILLAGE, Colo. , March 23, 2017  Agriculture ... in Series A financing and note conversion to commercialize ... Cool Planet is focused on developing products that are ... nearly $30 million in the last 18 months. This ... and North Bridge Venture Partners. The ...
(Date:3/23/2017)... La. (PRWEB) , ... March 23, 2017 , ... ... industrial monitoring solutions, today announced the hire of Dr. Sigmund “Sig” Floyd as ... customer applications, strategic partnerships and joint development activities. , “Dr. Floyd’s career has ...
(Date:3/22/2017)... Worcester, Mass. (PRWEB) , ... March 22, 2017 ... ... to scale up human tissue regeneration from small lab samples to full-size tissues, ... injuries: how to establish a vascular system that delivers blood deep into the ...
Breaking Biology Technology: