Navigation Links
Fertility hope as study shows eggs survive in older ovaries

In research that could have broad implications for women's fertility treatments, scientists have found that despite their age, female mice have a renewable egg supply in their ovaries.

The discovery, by Professor Jock Findlay from Prince Henry's Institute and Associate Professor Jeff Kerr from Monash's Department of Anatomy and Cell Biology, has sparked controversy among biologists and challenged the theory, held for more than 50 years, that female mammals are born with a finite number of oocytes (eggs).

Two years ago, international researchers speculated that mice could continue to produce eggs throughout puberty and adulthood. Although their speculation caused debate throughout the scientific community, the scientists could not produce evidence to confirm their idea. However, Professor Findlay and Dr Kerr's research gives support to the theory. Their findings have been published in the July issue of Reproduction.

In the mammalian ovary, reproductive cells called oocytes (eggs) develop within ovarian follicles. In humans, the eggs are believed to die off from late in foetal life, after birth and into adult life. When egg numbers decline towards zero females can no longer reproduce ?resulting in the condition we know as menopause.

Professor Findlay, Dr Kerr and their colleagues have found that the total number of eggs in young and normal healthy adult female mice do not decline over time and that overall egg number is maintained for longer than previously thought. Their research suggests that mice have a source of renewable oocytes, Professor Findlay said.

"The mechanism behind renewable oocytes is still unknown," he said. "Although other scientists have suggested that the new eggs come from stem cells in the bone marrow or the ovary, we really don't know and further experimentation is needed to find out."

Dr Kerr said the phenomenon of egg regeneration in mice did not necessarily mean the same happened in humans. " But the mechanism could provide direction for ovarian stem cell research and help women with fertility conditions," he said.

One in six Australian couples faces some form of infertility. Due to the limitations and sensitivity of human ovaries, few studies have been conducted into the factors that influence egg survival, growth or death in relation to fertility.


'"/>

Source:Research Australia


Related biology news :

1. Fertility drugs given all-clear in new study
2. Bioartificial kidney under study at MCG
3. W.M. Keck Foundation funds study of friendly microbes
4. Yellowstone microbes fueled by hydrogen, according to U. of Colorado study
5. Genome-wide mouse study yields link to human leukemia
6. Clam embryo study shows pollutant mixture adversely affects nerve cell development
7. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
8. Same mutation aided evolution in many fish species, Stanford study finds
9. Sequencing of marine bacterium will help study of cell communication
10. Genetically modified rice in China benefits farmers health, study finds
11. A new study examines how shared pathogens affect host populations
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/11/2017)... PALM BEACH GARDENS, Fla. , April 11, ... biometric identity management and secure authentication solutions, today ... million contract by Intelligence Advanced Research Projects Activity ... technologies for IARPA,s Thor program. "Innovation ... the onset and IARPA,s Thor program will allow ...
(Date:4/5/2017)... 5, 2017  The Allen Institute for Cell Science ... a one-of-a-kind portal and dynamic digital window into the ... the first application of deep learning to create predictive ... lines and a growing suite of powerful tools. The ... and future publicly available resources created and shared by ...
(Date:3/30/2017)... LOS ANGELES , March 30, 2017  On ... Hack the Genome hackathon at ... This exciting two-day competition will focus on developing health ... experience. Hack the Genome is ... has been tremendous. The world,s largest companies in the ...
Breaking Biology News(10 mins):
(Date:4/19/2017)... ... April 19, 2017 , ... ... (C. diff) infections through education and advocacy. Founded in 2010 in memory ... C. diff infection, the foundation has become the most-consulted source for patient-focused information ...
(Date:4/19/2017)... April 19, 2017  As a Bronze ... Heroin Summit ,  Proove┬« Biosciences, Inc. announces ... environmental, and lifestyle factors to accurately predict prescription ... of Southern California (USC), the Interventional Pain Institute ... publish results showing that Proove Opioid Risk┬« accurately ...
(Date:4/19/2017)... 19, 2017   Thermo Fisher Scientific Inc ... Procalcitonin MOnitoring SEpsis (MOSES) Study have been published ... Critical Care Medicine . Researchers from the study, ... Patients: Results From the Multicenter Procalcitonin MOnitoring SEpsis ... PCT (procalcitonin) assay to assess risk for 28 ...
(Date:4/18/2017)... (PRWEB) , ... April 18, 2017 , ... For a ... Associates, co-members in the VaxCorps vaccine consortium, were named one of the top two ... since the inception of this category; winning the award four times previously, and first ...
Breaking Biology Technology: