Navigation Links
Feds give researchers ok for safety test of adult stem cells in patients with heart disease

development for the treatment of patients.

"Traditionally, physicians have been able to prevent heart attack or alleviate its after-effects, but they have not figured out how to initiate the sort of blood vessel repair that remains a key to survival," says Dr. Laughlin. "Now there is a promise of achieving that repair by infusing highly selected marrow stem cells."

Upon acceptance in the study, patients with blocked or damaged heart vessels will be assigned to one of three groups, each made up of three to four patients who will receive a preset dose of stem cell therapy. They will have stem cells drawn from their own bone marrow. These cells will then be enriched in the laboratory and injected into the patients at the site of their ischemia.

The Phase I study is being conducted at University Hospitals of Cleveland with support from the National Institutes of Health, Case Western Reserve University, and Cleveland-based Arteriocyte.

Blocked or damaged blood vessels are a major cause of illness and death around the world. Atherosclerosis, for example, can lead to congestive heart failure and heart attacks. About 5 million people in the United States have heart failure and the number is growing. Each year, another 550,000 people are diagnosed for the first time. It contributes to or causes about 300,000 deaths each year. About 1 percent of the U.S. population over the age of 65 is diagnosed with congestive heart failure each year. Existing therapies include drugs, gene therapy, and vascular interventions for relief of arterial obstructions.

In 2003, approximately 750,000 coronary artery bypass graft (CABG) surgeries were performed worldwide and approximately 1.8 million balloon angioplasty procedures were performed. While these interventional therapies are now the standard of care, there are still a significant number of people for whom these methods do not work, or who have blockage throughout their bodies.


'"/>

Source:Case Western Reserve University


Page: 1 2

Related biology news :

1. NYU researchers simulate molecular biological clock
2. Vital step in cellular migration described by UCSD medical researchers
3. ASU researchers finds novel chemistry at work to provide parrots vibrant red colors
4. UCSD researchers maintain stem cells without contaminated animal feeder layers
5. Why do insects stop breathing? To avoid damage from too much oxygen, say researchers
6. New protein discovered by Hebrew University researchers
7. First real-time view of developing neurons reveals surprises, say Stanford researchers
8. Agilent Technologies releases automated literature search tool for biology researchers
9. Self-assembled nano-sized probes allow Penn researchers to see tumors through flesh and skin
10. Yale researchers identify molecule for detecting parasitic infection in humans
11. US life expectancy about to decline, researchers say
Post Your Comments:
(Date:12/3/2009)A coating on windows or solar panels that repels grime and dirt? Expanded battery storage capacities for the next electric car? New Tel Aviv University research, just published in Nature Nanotechnolo
(Date:12/3/2009)ALBUQUERQUE, N.M. Most scientists believe that staph infections are caused by many bacterial cells that signal each other to emit toxins. The signaling process is called quorum sensing because many b
(Date:12/3/2009)Have you ever felt overly upset by a social snubbing? Your genetics, not your friends, may be at fault. , Scientists have long known that opium-like painkillers, called opioids, relieve not only phys
Breaking Biology News(10 mins):A window that washes itself? 2Stopping MRSA before it becomes dangerous is possible, Sandia/UNM researchers find 2Stopping MRSA before it becomes dangerous is possible, Sandia/UNM researchers find 3Endoscopy within 24 hours shows better outcomes in elderly with peptic ulcer bleeding 54683 1Endoscopy within 24 hours shows better outcomes in elderly with peptic ulcer bleeding 54683 2Endoscopy within 24 hours shows better outcomes in elderly with peptic ulcer bleeding 54683 3Endoscopy within 24 hours shows better outcomes in elderly with peptic ulcer bleeding 54683 4Special Stem Cells Build Biological Bypass 54680 1Special Stem Cells Build Biological Bypass 54680 2Breckenridge Pharmaceutical Enters Agreement with Orit Laboratories 28West Caldwell NJ 29 to Market Ergocalciferol 28Vitamin D 29 Capsules 54676 1Breckenridge Pharmaceutical Enters Agreement with Orit Laboratories 28West Caldwell NJ 29 to Market Ergocalciferol 28Vitamin D 29 Capsules 54676 2
...epends share an attribute with paper airplanes: Un...researchers have been puzzled by how the long, lin... in a cell are folded into the shapes they must as...wn that for many of the most complex and essential...idden in the inner cavity of a type of molecule ca...
...t there are more bee species than previously thoug...in over a hundred years, John S. Ascher, a researc...y at the American Museum of Natural History, compi... more than 19,200 described bee species, showcasin...is new species inventory documents 2,000 more desc...
...es, a healthy immune system, protection against so... yet another item for the expanding list of vitami...eeps the heart, the body,s long-distance runner, f...harmacologist Robert U. Simpson, Ph.D., thinks it,... , In studies in rats, Simpson and his team repor...
Other Biology News:Researchers reveal insights into hidden world of protein folding 2Researchers reveal insights into hidden world of protein folding 3Researchers reveal insights into hidden world of protein folding 4Bee species outnumber mammals and birds combined 2Vitamin D: New way to treat heart failure? 2Vitamin D: New way to treat heart failure? 3
(Date:12/2/2009)NEW YORK, Dec. 2 Nearly 600 medical research executives, scientists, policy makers, and funders today convened to explore novel development approaches and innovative funding strategies at the inaugur
(Date:12/2/2009)LELYSTAD, The Netherlands, December 2 Pepscan Holding NV,the Netherlands based biotechnology company focusing on protein mimicking,technology for the generation of immune therapeutics today announced
(Date:12/2/2009)NANJING, China, Dec. 2 /PRNewswire-Asia/ -- Simcere Pharmaceutical Group,("Simcere" or the "Company") (NYSE: SCR ), a leading pharmaceutical company,specializing in the development, manufacturing, a
(Date:12/1/2009)Dr. Kerry Solomon announced that he has joined Carolina Eyecare Physicians and has launched his redesigned website at www.DrKerrySolomon.com , which was developed by Medical Consulting Group. Dr. So
Breaking Biology Technology:Medical Research Leaders Explore Novel Strategies to Expedite the Search for Cures 2Dutch Biotech Company Pepscan Appoints New CEO 2Simcere Announces 105 Drugs Included in China's National Drug Reimbursement List 2Simcere Announces 105 Drugs Included in China's National Drug Reimbursement List 3Charleston LASIK and Cataract Expert Dr. Kerry Solomon Opens New Practice and Launches DrKerrySolomon.com 2Charleston LASIK and Cataract Expert Dr. Kerry Solomon Opens New Practice and Launches DrKerrySolomon.com 3Charleston LASIK and Cataract Expert Dr. Kerry Solomon Opens New Practice and Launches DrKerrySolomon.com 4Charleston LASIK and Cataract Expert Dr. Kerry Solomon Opens New Practice and Launches DrKerrySolomon.com 5Charleston LASIK and Cataract Expert Dr. Kerry Solomon Opens New Practice and Launches DrKerrySolomon.com 6
...ONG, Sept. 7 /Xinhua-PRNewswire-FirstCall/ -- Chin...: CTDC; "CTDC" or the "Company") today,announced t...olar energy,sector. With strong government commitm...able energy in the coming decades and rising energ...trategy will deliver shareholder,value and higher ...
...f=Astoria Hotel New York City 5:30-7:30 p.m. (ET),...), a medical device company focused on developing ...nts for the spine, announced today,that it will ho...rs and,analysts at the Waldorf=Astoria Hotel in Ne...30 p.m. to 7:30 p.m. ET. The reception will be ho...
...LLE, Md., Sept. 7 Human Genome,Sciences, Inc. (Na...n at the,Bear Stearns 20th Annual Healthcare Confe...sed at http://www.hgsi.com (Logo: http://www.n...ber of Human Genome Sciences, senior management te...day, September 11, 2007 at 4:00 pm,Eastern Time. ...
Other Biology Technology:China Technology Announces Entry to the Solar Energy Sector 2China Technology Announces Entry to the Solar Energy Sector 3NuVasive to Host Investor Reception on September 11, 2007 2NuVasive to Host Investor Reception on September 11, 2007 3NuVasive to Host Investor Reception on September 11, 2007 4
Mouse Anti-Human Serpin A3 Monoclonal Antibody, Unconjugated, Clone 213907 from R&D Systems
Sheep Growth Hormone from Cell Sciences
Goat Anti-Human SorCS1 Polyclonal Antibody, Unconjugated from R&D Systems
Goat Anti-Viral CCI Polyclonal Antibody, Biotin Conjugated from R&D Systems
Biology Products: