Navigation Links
Fat stem cells being studied as option for breast reconstruction

Breast cancer survivors might one day avoid the prospect of invasive breast reconstruction surgery, opting instead for an approach that would involve using stem cells derived from their own fat, suggest University of Pittsburgh researchers who are studying the potential these cells may have for regenerating new breast tissue.

In animal models, the researchers hope to prove that an injection of fat-derived stem cells that are seeded onto microscopic scaffold structures will enable the production of a durable, replacement soft tissue. The team, led by J. Peter Rubin, M.D., assistant professor of plastic and reconstructive surgery at the University of Pittsburgh School of Medicine, recently received a three-year grant from the National Cancer Institute to further explore this unique approach.

"The surgical options for breast reconstruction involve either the use of implants or a procedure whereby fat tissue taken from another part of the body is shaped into the form of a breast. Neither is ideal nor without risk. The use of adipose- or fat-derived stem cells may represent a better solution for soft tissue reconstruction in breast cancer patients," said Dr. Rubin, who also is co-director of the Aesthetic Surgery Center at the University of Pittsburgh Medical Center.

The use of stem cells to treat disease or regenerate tissue is believed to hold promise because of their potential to develop into different specialized cell types. Indeed, when exposed to specific conditions in the laboratory, fat-derived stem cells have been shown to differentiate into cells characteristic of those from tissues such as fat, bone, cartilage, nerve, muscle and blood vessels.

Dr. Rubin and his colleagues are focusing their efforts on an approach that involves combining the fat-derived stem cells with microscopic beads composed of a type of extracellular matrix (ECM) that has regenerative properties. Preliminary results indicate that the stem cells can ea
'"/>

Source:University of Pittsburgh Medical Center


Page: 1 2

Related biology news :

1. Wisconsin scientists grow critical nerve cells
2. Spleen may be source of versatile stem cells
3. Researchers discover way to make cells in the eye sensitive to light
4. Priming embryonic stem cells to fulfill their promise
5. Lack of enzyme turns fat cells into fat burners
6. Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas
7. Elusive HIV shape change revealed; Key clue to how virus infects cells
8. Mouse brain cells rapidly recover after Alzheimers plaques are cleared
9. Enzyme allows B cells to resist death, leading to leukemia
10. Scientists rid stem cell culture of key animal cells
11. Genetically modified natural killer immune cells attack, kill leukemia cells
Post Your Comments:
(Date:7/24/2008)...), a new family of genes discovered by researchers...olecular Medicine in Temple University,s College o...ptosis or programmed cell death. , NSPs were di...toral student at the University and now an assista...e Cardeza Foundation, and Antonio Giordano, direct...
(Date:7/24/2008)...ently burning through a study area where projectio.... Managers used data and analysis from the Gotchen...ning, analysis, and implementation of treatments n...The Gotchen LSR, lies on the east slope of the Cas...acres of the Mount Adams Ranger District on the Gi...
(Date:7/24/2008)... storage in western U.S. forests , Active fire ...caused a widespread increase in fire-intolerant tr...ng on trees within western U.S. forests. These fac...to account for much of North America,s carbon sink...s, Fellows and Goulden compare California forest i...
(Date:7/23/2008)...ons people on low-carbohydrate diets may lose weig... type of sugar that can be made into body fat quic...Medical Center. , Dr. Elizabeth Parks, associa... of a study appearing in a current issue of the J...gest that the right type of carbohydrates a person...
Breaking Biology News(10 mins):Novel structure proteins could play a role in apoptosis 2Landscape study may offer solutions for fire managers 2AGU journal highlights -- July 23, 2008 2AGU journal highlights -- July 23, 2008 3AGU journal highlights -- July 23, 2008 4AGU journal highlights -- July 23, 2008 5AGU journal highlights -- July 23, 2008 6AGU journal highlights -- July 23, 2008 7AGU journal highlights -- July 23, 2008 8Limiting fructose may boost weight loss, UT Southwestern researcher reports 2Limiting fructose may boost weight loss, UT Southwestern researcher reports 3Phoenix Academys Therapeutic Community Model Is First to be Federally Recognized as Evidence Based 12673 1Phoenix Academys Therapeutic Community Model Is First to be Federally Recognized as Evidence Based 12673 2Media highlights in the March 1 issue of Biophysical Journal 2310 1Sunrise Announces Release Date for Fourth Quarter Preliminary Selected Financial and Operating Data 12666 1Doing Angioplasty Long After Heart Attack Still Worth It Analysis Shows 12661 1Doing Angioplasty Long After Heart Attack Still Worth It Analysis Shows 12661 2
...e Research Institute (NHGRI), part of the National...s awarded grants totaling more than $32 million to...technologies intended to reduce the cost of DNA se...cal research and health care. , "The efforts are a...tion of sequencing technologies become available i...
...nfections may create autoimmune response , New re...evolutionary changes that would allow it to produc...ved antibodies would be far more likely to attack ...finds the immune system has evolved a near-perfect...fective against pathogens and unlikely to cause au...
...ol of Medicine have found that 85 percent of embry...to become live births, highlighting the need for i...embryos. , Published in the August issue of Fertil...of U.S. statistics from all the fertility clinics ...tor of the Yale Fertility Center, Pasquale Patrizi...
...dicine is an ongoing challenge to blood services w...dt-Jakob Disease (vCJD), emerge. An update on the ...an form of Bovine Spongiform Encephalopathy (BSE),...k of transmission through blood transfusion was pr... Transfusion Congress. At the "Safety in Transfusi...
Other Biology News:NHGRI expands effort to revolutionize sequencing technologies 2NHGRI expands effort to revolutionize sequencing technologies 3NHGRI expands effort to revolutionize sequencing technologies 4NHGRI expands effort to revolutionize sequencing technologies 5Immune system has evolved to prevent autoimmune disease 2Immune system has evolved to prevent autoimmune disease 3New results validating Pall prion reduction filter disclosed at ISBT Congress 2New results validating Pall prion reduction filter disclosed at ISBT Congress 3
(Date:7/24/2008)...re/ -- The Global Probiotics Council,(GPC), a comm...ult Honsha,Co., Ltd., announced the two awardees w...rant for Probiotics Research (YIGPRO) today. The p...who will continue to contribute to,the advancement...United,States., Ajay S. Gulati, MD, an Assistant ...
(Date:7/24/2008)... Important Advance in Radiofrequency ...if., July 24 /- PEAK Surgical, Inc., ...tissue dissection system,based on a proprietary te...rug Administration has granted the company 510(k) ... use in general surgery. The PEAK Surgery System,c...
(Date:7/24/2008)...ire/ -- Sagent Pharmaceuticals, Inc.,a privately-...nced that it,has launched ceftazidime for injectio...m antibiotic. Sagent will offer ceftazidime in 1,a...ge vials. According to,IMS data, 2007 sales of inj...ximately $45.7 million., "Sagent is proud to be p...
(Date:7/24/2008)...swire-FirstCall/ -- United,Therapeutics Corporatio...lease its 2008 second quarter financial results be...., United Therapeutics will host a half-hour tele.... Eastern Time. The teleconference is accessible,b...rs dialing,1-706-679-8129. A rebroadcast of the te...
Breaking Biology Technology:Global Probiotics Council Announces First Awardees for New Young Investigator Grant for Probiotics Research 2Global Probiotics Council Announces First Awardees for New Young Investigator Grant for Probiotics Research 3Global Probiotics Council Announces First Awardees for New Young Investigator Grant for Probiotics Research 4PEAK Surgical Receives 510(k) Clearance to Market PEAK(R) Surgery System for Use in General Surgery 2PEAK Surgical Receives 510(k) Clearance to Market PEAK(R) Surgery System for Use in General Surgery 3PEAK Surgical Receives 510(k) Clearance to Market PEAK(R) Surgery System for Use in General Surgery 4Sagent Pharmaceuticals Launches Ceftazidime for Injection, USP 2
...ith the presidential primaries less than a year aw...apture the hearts of their party,s voters. Interes...y to make their hearts known long before they reac...t democratic in modern history, thanks to blogs an...rough all that content will be a challenge for vot...
...dison, Wis. The technology industry in Dane Count...nt years, and its ranks grew to 510 businesses, ac... of High-Tech Companies published by Madison Gas ...nnual directory, which will be released next week,...rs. They reported more than $5.5 billion in combin...
...ookfield, Wis . - Leslie Muma, who led the technol...t prosperous periods, is one of four executives wh...usiness Hall of Fame. , ,Muma, who was Fiserv,s pr...999, when he was named CEO, helped grow the Brookf...siness to a publicly traded company reporting $4.1...
...dison, Wis . - Calling President Bush severely o...ine other governors in calling for passage of a bi...cell research. , ,The pending legislation, Senate ... 2007 - is being debated in the Senate. It would e...sed by Bush in 2001. , ,Doyle urged passage of the...
Other Biology Technology:Tired of the spin? ExpertVoter website makes candidate selection easier 2Tired of the spin? ExpertVoter website makes candidate selection easier 3Directory shows high-tech growth spurt in Dane Co. 2Directory shows high-tech growth spurt in Dane Co. 3Directory shows high-tech growth spurt in Dane Co. 4Doyle joins governors in support of stem cell bill 2
Standard 2" and 3" Fiberboard Boxes can be sold separately or with 16, 25, 36, 49, 64, 81 or 100 cell dividers. Fiberboard boxes can also be ordered with corresponding freezer racks
Whole blood is collected from mice (Swiss Webster, 8-10 weeks old,either sex) and processed within 45 minutes of collection. The complement is then filtered and pooled on ice, bottled and stored at -
Anti-HMGN2/HMG-17 Immunogen : Recombinant human HMGN2/HMG-17 Formulation: 0.2M Tris-glycine, pH7.4, 5mg/ml BSA, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30% Quality Assuranc
...MMP-3, Human, Assay, 96 wells. ELISA.Specific for...d complexed MMP-3. No cross-reactivity with MMP-1,...ng/ml.Suitable for use with cell culture supernata...l.Store at -15 to -30 C. Category: Drug Screening...
Biology Products: