Navigation Links
Fat overrides effects of vitamin C

Fats in our stomach may reduce the protective effects of antioxidants such as vitamin C. Scientists at the University of Glasgow found that in the presence of lipid the ability of antioxidants, such as ascorbic acid (the active component of vitamin C), to protect against the generation of potential cancer-forming compounds in the stomach is less than when no lipids are present. “Our results illustrate how diet can influence gastric biochemistry? says Emilie Combet, the post-doctoral researcher working on the project, who will be presenting her results at the Society of Experimental Biology’s Annual Main Meeting on Monday 2nd of April.

The incidence of cancer of the proximal stomach has been increasing over the last 20 years for which environmental factors, such as diet, certainly play a part. Nitrite, which is present in our saliva and is derived from nitrate in our diet, is thought to be a pre-carcinogen for gastric cancer. When it is swallowed and enters the acidic environment of the stomach, nitrite spontaneously forms nitrosating species able to convert a range of targets, such as secondary amines and bile acids, into carcinogenic N-nitrosocompounds. Antioxidants such as ascorbic acid protect against the formation of these nitrosocompounds by converting the nitrosating species back into nitric oxide (NO). However, NO diffuses rapidly to lipids, where it reacts with oxygen to reform nitrosating species. The presence of lipids therefore overrides the protective effect of vitamin C against the formation of harmful compounds.

Source:Society for Experimental Biology

Page: 1

Related biology news :

1. Scientists ID molecular switch in liver that triggers harmful effects of saturated and trans fats
2. Alcohols effects on gene expression in the central nervous system
3. Scientists discover how plants disarm the toxic effects of excessive sunlight
4. Physiological effects of reduced gravity on bacteria
5. Protein prevents detrimental immune effects of bacterial sepsis
6. The ecological effects of the Chernobyl disaster
7. Jefferson researchers find nanoparticle shows promise in reducing radiation side effects
8. Greasing interferons gears may pave way to greater therapeutic benefits, fewer side effects
9. Young scientists turn to gel to ease side-effects of cancer treatment
10. Losing sleep undoes the rejuvenating effects new learning has on the brain
11. Gene therapy protects mice from the effects of whole-body irradiation
Post Your Comments:

(Date:11/12/2015)... -- A golden retriever that stayed healthy despite having the ... a new lead for treating this muscle-wasting disorder, report ... MIT and Harvard and the University of São Paolo ... Cell, pinpoints a protective gene that boosts muscle ... Boston Children,s lab of Lou Kunkel , PhD, ...
(Date:11/11/2015)... --  MedNet Solutions , an innovative SaaS-based eClinical technology company ... to announce that it will be a Sponsor of the ... be held November 17-19 in Hamburg , ... iMedNet , MedNet,s easy-to-use, proven and affordable ... been able to deliver time and cost savings of up ...
(Date:11/9/2015)... , Nov. 09, 2015 ... the addition of the "Global Law ... their offering. --> ) ... "Global Law Enforcement Biometrics Market 2015-2019" ... Research and Markets ( ) has ...
Breaking Biology News(10 mins):
(Date:11/25/2015)... ... November 25, 2015 , ... Jessica Richman ... AngelList early in their initial angel funding process. Now, they are paying it ... to make early stage investments in the microbiome space. In this, they ...
(Date:11/24/2015)... Halozyme Therapeutics, Inc. (NASDAQ: HALO ) will be ... York on Wednesday, December 2 at 9:30 a.m. ET/6:30 ... CEO, will provide a corporate overview. th Annual ... 1:00 p.m. ET/10:00 a.m. PT . Jim Mazzola , ... corporate overview. --> th Annual Oppenheimer Healthcare Conference ...
(Date:11/24/2015)... Nov. 24, 2015 /PRNewswire/ - Aeterna Zentaris Inc. (NASDAQ: ... on behalf of the Toronto Stock Exchange, confirms that ... are no corporate developments that would cause the recent ... --> --> About Aeterna Zentaris Inc. ... --> Aeterna Zentaris is a specialty biopharmaceutical ...
(Date:11/24/2015)... (PRWEB) , ... November 24, 2015 , ... The Academy ... Special Interest Group (SIG), MultiGP, also known as Multirotor Grand Prix, to represent the ... last few years. Many AMA members have embraced this type of racing and several ...
Breaking Biology Technology: