Navigation Links
Fast and slow -- How the spinal cord controls the speed of movement

Using a state-of-the-art technique to map neurons in the spinal cord of a larval zebrafish, Cornell University scientists have found a surprising pattern of activity that regulates the speed of the fish’s movement. The research may have long-term implications for treating injured human spinal cords and Parkinson’s disease, where movements slow down and become erratic.

The study, "A Topographic Map of Recruitment in Spinal Cord," published in the March 1 issue of the journal Nature, maps how neurons in the bottom of the fish’s spinal cord become active during slow movements, while cells further up the spinal cord activate as movements speed up.

By removing specific neurons in the lower spinal cord with laser beams, the researchers rendered the fish incapable of slow movements. By removing nerves further up the backbone, the fish had difficulty moving fast.

"No one had any idea that organization like this existed in a spinal cord," said Joseph Fetcho, a Cornell professor of neurobiology and behavior and an author of the study. "Now that we know the pattern, we can begin to ask how that changes in disease states."

David McLean, Cornell postdoctoral researcher in Fetcho’s laboratory, was the first person to discover the pattern of neural activation and how it was associated with speed of movement. He is the lead author on the study.

The researchers worked with 4 millimeter-long larval zebrafish (Danio rerio) because they are transparent and researchers can see their cells. Fetcho and his colleagues injected the fishes?spinal cords with a fluorescent dye, which then lit up when calcium ions flooded in as the nerve cells activated. A confocal microscope with lasers allowed the researchers to image the cells at very high resolutions. Using this set up, they watched nerve cells light up as the animals moved at different speeds.

While no one knows how this pattern relates to other vertebrates, the research opens a door
'"/>

Source:Cornell University News Service


Page: 1 2

Related biology news :

1. Stem cell treatment improves mobility after spinal cord injury
2. Combination therapy leads to partial recovery from spinal cord injury in rats
3. Purdue scientists may have found key to halting spinal cord damage
4. Researchers find molecule that inhibits regrowth of spinal nerve cells
5. Gradient guides nerve growth down spinal cord
6. One small step means giant leap for spinal cord research
7. New study identifies key gene in development of connections between brain and spinal cord
8. Protein fingerprint in spinal fluid could spot Alzheimers disease
9. Thinking with the spinal cord?
10. Elderly spinal cord injuries increase five-fold in 30 years, Jefferson neurosurgeons find
11. Cooperation is key—a new way of looking at MicroRNA and how it controls gene expression
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Fast and slow How the spinal cord controls the speed movement

(Date:8/24/2015)... South Africa , August 24, 2015 ... Germany ,s largest biometrics manufacturer DERMALOG and its ... with the "2015 African Biometrics Company of the Year Award". ... Nigeria .   -Cross reference: ... http://www.presseportal.de/nr/8896 - On Thursday evening, in ...
(Date:8/20/2015)... -- NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or ... growing mobile commerce market and creator of the Wocket® ... Alliance and the EMV Migration Forum.  ... Alliance Latin America (SCALA) Chapter provides NXT-ID, Inc. direct ... promoting adoption of smart card technology. To ...
(Date:8/17/2015)... , Aug. 17, 2015  NXT-ID, Inc. (NASDAQ: ... authentication company focused on the growing mobile commerce market ... new sales campaign for Q4 2015. The new marketing ... team consisting of Amplitude Marketing Group ( http://amplitudemarketing.com/ ) ... Group is a leader in retail driven marketing and ...
Breaking Biology News(10 mins):Frost & Sullivan Honors DERMALOG with Biometrics Prize for Achievements in Africa 2Frost & Sullivan Honors DERMALOG with Biometrics Prize for Achievements in Africa 3NXT-ID, Inc. Joins Smart Card Alliance and EMV Migration Forum 2NXT-ID, Inc. Joins Smart Card Alliance and EMV Migration Forum 3NXT-ID, Inc. Joins Smart Card Alliance and EMV Migration Forum 4NXT-ID, Inc. Launches Sales Campaign for Wocket Smart Wallet with Award Winning Marketing Team 2NXT-ID, Inc. Launches Sales Campaign for Wocket Smart Wallet with Award Winning Marketing Team 3
... available in German . , At the ... FZI Research Center for Information Technology will present innovations for ... G33 in hall 26, a humanoid kitchen robot will move ... algorithms will be presented to protect data in the cloud. ...
... from Karolinska Institutet in Sweden shows that a new ... ACR16 might operate via previously unknown mechanisms of ... ACR16 binds to the sigma-1 receptor, a protein in ... new knowledge can be used to develop future treatments ...
... school takes off in fear, tipped off by a mysterious substance ... online on February 23 in the Cell Press journal Current ... made of. Within that chemical brew is a special ... fish is wounded, fragments of the sugar known as chondroitin sulfate ...
Cached Biology News:CeBIT: Robot obeys commands and gestures 2CeBIT: Robot obeys commands and gestures 3CeBIT: Robot obeys commands and gestures 4New knowledge on the pharmacology of dopamine stabilizers 2For fish, fear smells like sugar 2
(Date:8/31/2015)... , Aug. 31, 2015 LabStyle Innovations ... Management Solution, today announced it recently closed a ... will be used to support the global rollout ... a mobile, cloud-based, diabetes management solution that includes ... pocket-sized, blood glucose monitoring device, and for working ...
(Date:8/31/2015)... ... August 31, 2015 , ... ... most successful food and beverage processors, equipment manufacturers and leaders in the field ... and industrial weighing and formulation for manufacturers of bakery and snacks; beverages; dairy; ...
(Date:8/30/2015)... England , August 31, 2015 /PRNewswire/ ... 51-jährige Wartezeit   einer Frau   für chirurgische   ... Alter von 7-90   werden für eine ... Programm soll 1200 Frauen behandeln und die Anzahl ausgebildeter ... Astellas gab heute bekannt, dass  Action ...
(Date:8/28/2015)... IRVINE, CA (PRWEB) , ... August 28, 2015 ... ... leader in Personalized Medicine, presented two studies at the International Spine Intervention ... on July 28th, 2015 through to August 1st, 2015. With a focus on ...
Breaking Biology Technology:LabStyle Innovations Closes $2.5 Million Funding to Support Global Rollout of Dario Diabetes Management Solution 2LabStyle Innovations Closes $2.5 Million Funding to Support Global Rollout of Dario Diabetes Management Solution 3LabStyle Innovations Closes $2.5 Million Funding to Support Global Rollout of Dario Diabetes Management Solution 4METTLER TOLEDO Hosts Food Safety Educational Center at 2015 PROCESS EXPO 2Über 550 Frauen, deren Leben durch "Action on Fistula" transformiert wurde 2Über 550 Frauen, deren Leben durch "Action on Fistula" transformiert wurde 3Über 550 Frauen, deren Leben durch "Action on Fistula" transformiert wurde 4Über 550 Frauen, deren Leben durch "Action on Fistula" transformiert wurde 5Proove Biosciences Presents New Research Study at the International Spine Intervention Society’s Annual Scientific Meeting 2Proove Biosciences Presents New Research Study at the International Spine Intervention Society’s Annual Scientific Meeting 3Proove Biosciences Presents New Research Study at the International Spine Intervention Society’s Annual Scientific Meeting 4
... raised questions over a billion dollar industry by boldly ... nanotechnology materials can be mass produced. In ... Publishing,s journal Nanotechnology , Professor Mike Kelly, Centre ... that you cannot mass produce structures with a diameter ...
... professor at the University of California, Riverside,s Bourns ... for his pioneering work in nanotechnology that could ... Balandin, a professor of electrical engineering and founding ... Program, was selected to receive the Pioneer of ...
... Mylan Inc. (Nasdaq: MYL ) announced today ... on Tuesday, May 3, 2011, at 8:30 a.m. ET, to ... which ended March 31, 2011. Mylan will release its financial ... The dial-in number to access the call is 800.479.9001 or ...
Cached Biology Technology:Limit to nanotechnology mass-production? 2Engineering professor wins award for pioneering work expected to improve electronic devices 2