Navigation Links
FDA causes unnecessary scare about common painkillers

The U.S. Food and Drug Administration (FDA) has caused an unnecessary scare about some pain relievers by adding a warning to drugs that are safe, says Curt Furberg, M.D., Ph.D., from Wake Forest University School of Medicine. At the same time, he says the agency has failed to recognize the harm of a pain reliever that should be taken off the market.

"The FDA is adding 'black box' warnings to all prescription and over-the-counter pain relievers ?even to naproxen ?which the evidence shows is safe," said Furberg, who serves on the FDA Drug Safety and Risk Management Advisory Committee. "This is based on the false assumption that all nonsteroidal anti-inflammatory drugs increase the risk of heart attacks. In fact, there are major differences between these agents."

In a commentary published by Trials (http://www.trialsjournal.com/content/8/1/13), an online journal of BioMed Central, Furberg says the FDA has failed to recognize current scientific evidence when it made decisions on the safety of nonsteroidal anti-inflammatory drugs (NSAIDs) that are often used to treat the pain or inflammation from arthritis.

The most commonly used NSAIDs are ibuprofen (Advil®), naproxen (Aleve®), and diclofenac (Voltaren®). There are more than a dozen others, including drugs such as celecoxib (Celebrex®) that are in a special class known as selective COX-2 inhibitors because of the hormone they target. The other NSAIDs are known as "non-selective."

Furberg said while the evidence for the non-selective NSAIDs is somewhat limited, an analysis combining several small studies found that high doses (500 mg twice daily) of Aleve were not associated with an increased risk of heart attacks compared to a placebo, or an inactive pill.

On the other hand, high doses of Advil (800 mg three times a day) and Voltaren (75 mg twice daily) were associated with rates of heart attack that were 51 percent
'"/>

Source:Wake Forest University Baptist Medical Center


Page: 1 2

Related biology news :

1. BRCA1 causes ovarian cancer through indirect, biochemical route
2. Researchers discover molecule that causes secondary stroke
3. NASA study finds snow melt causes large ocean plant blooms
4. Alarm pheromone causes aphids to sprout wings
5. One hit of crystal meth causes birth defects
6. University of Nevada, Reno research team discovers hormone that causes malaria mosquito to urinate
7. Gene discovery sheds light on causes of rare disease, cancer
8. Defect in gene causes neuralgic amyotrophy
9. Genomics researchers discover protein deficit that causes drug toxicity
10. Variant prion protein causes infection but no symptoms
11. Prenatal exposure to marine toxin causes lasting damage
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: FDA causes unnecessary scare about common painkillers

(Date:6/23/2015)... June 22, 2015 ... addition of the "Body-Worn Temperature Sensors Market ... and Forecast 2014 - 2020" report to ... analysis of the global body-worn temperature sensors market. ... segmented on the basis of types, care setting, ...
(Date:6/18/2015)... This report analyzes the worldwide markets for ... Segments, which includes Immunoassay Analyzers and Reagents: Enzyme Immunoassay ... Systems, and Nephelometric Immunoassay Systems. The report provides separate ... , Japan , Europe ... Latin America , and Rest of World. Annual ...
(Date:6/17/2015)... Germany , June 17, 2015 ... Standard: QIA) today launched new Investigator ® STR assay ... the United States . The new genetic ... key genomic markers (short tandem repeats or STRs) for DNA ... evaluate the quality of DNA in each sample, a novel ...
Breaking Biology News(10 mins):Body-Worn Temperature Sensors Market - Global Industry Analysis 2Global Immunoassay Systems Market 2Global Immunoassay Systems Market 3Global Immunoassay Systems Market 4Global Immunoassay Systems Market 5Global Immunoassay Systems Market 6Global Immunoassay Systems Market 7Global Immunoassay Systems Market 8Global Immunoassay Systems Market 9Global Immunoassay Systems Market 10Global Immunoassay Systems Market 11Global Immunoassay Systems Market 12Global Immunoassay Systems Market 13Global Immunoassay Systems Market 14Global Immunoassay Systems Market 15Global Immunoassay Systems Market 16Global Immunoassay Systems Market 17Global Immunoassay Systems Market 18Global Immunoassay Systems Market 19Global Immunoassay Systems Market 20Global Immunoassay Systems Market 21Global Immunoassay Systems Market 22Global Immunoassay Systems Market 23Global Immunoassay Systems Market 24Global Immunoassay Systems Market 25Global Immunoassay Systems Market 26Global Immunoassay Systems Market 27Global Immunoassay Systems Market 28Global Immunoassay Systems Market 29QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 2QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 3QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 4QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 5
... 2011 The collaboration of two leading cell image ... facility for archiving, sharing, and analyzing microscope images in ... (ASCB) and the National Center for Microscopy and Imaging ... (UCSD), have joined forces to provide a unified interface. ...
... University is subjecting chunks of rock to hellish conditions in ... change. By exposing a handful of rocks ... new data about the large-scale underground storage of carbon dioxide, ... "About 60 percent of the world,s carbon ...
... a deadly batch of spinach killed three people and sickened ... line have argued over how best to protect consumers and ... Now, a major, national initiative, led by University of Maryland ... more trustworthy salad fixings. It promises to be one of ...
Cached Biology News:2 top biological imaging centers offer powerful free online tool to researchers and public 2AGU meeting: Stanford scientists subject rocks to hellish conditions to combat global warming 2AGU meeting: Stanford scientists subject rocks to hellish conditions to combat global warming 3AGU meeting: Stanford scientists subject rocks to hellish conditions to combat global warming 4Salads you can trust -- safe farm practices get major test 2Salads you can trust -- safe farm practices get major test 3Salads you can trust -- safe farm practices get major test 4
(Date:6/29/2015)... 29, 2015  AACC, a global scientific and ... laboratory medicine, is pleased to announce that the ... , has increased to 7.9 in the 2014 ... Clinical Chemistry in the top 3% ... influence of the research it publishes on laboratory ...
(Date:6/29/2015)... , June 29, 2015 According ... (DNA, RNA, XNA), by Application (Diagnostics, Therapeutics, R&D), by Technology ... & Pharmaceutical Companies, CRO) - Global Forecast to 2020", published ... $244.93 Million by 2020 from $107.56 Million in 2015, at ... T ables and 67 F igures ...
(Date:6/29/2015)... , June 29, 2015   For the seventh year ... to assess their overall digital maturity called the ... these companies are not maturing fast enough. While it,s ... in numerous ways overall and customers are increasingly "digital ... of digital customer engagement.  ...
(Date:6/26/2015)... 26, 2015   Aratana Therapeutics, Inc ... therapeutics company focused on the licensing, development ... companion animals, today announced positive results from ... (AT-002), the company,s innovative therapeutic for appetite ... molecule that mimics ghrelin, the naturally occurring ...
Breaking Biology Technology:AACC's Journal, Clinical Chemistry, Continues to Have Significant Impact on Medical Testing, Healthcare 2AACC's Journal, Clinical Chemistry, Continues to Have Significant Impact on Medical Testing, Healthcare 3Aptamers Market Worth $244.93 Million by 2020 2Aptamers Market Worth $244.93 Million by 2020 3Aptamers Market Worth $244.93 Million by 2020 4Results from Digital Maturity Study Show Pharma Lagging 2Results from Digital Maturity Study Show Pharma Lagging 3Results from Digital Maturity Study Show Pharma Lagging 4Aratana Therapeutics Announces Positive Pivotal Results for AT-002 2Aratana Therapeutics Announces Positive Pivotal Results for AT-002 3Aratana Therapeutics Announces Positive Pivotal Results for AT-002 4Aratana Therapeutics Announces Positive Pivotal Results for AT-002 5
... to design computer chips and electronic circuitry for extreme ... electrical engineers at Vanderbilt University has developed all the ... thin films of nanodiamond. They have created diamond versions ... a key element in computers., "Diamond-based devices have the ...
... Mass., Aug. 4, 2011 Interleukin Genetics, Inc. ... call and Webcast on Friday, August 12 at 9:30 a.m. ... To access the live call, dial 877-324-1976 (domestic) or 631-291-4550 ... will be available on the Investors section of Interleukin Genetics, ...
... N.J., Aug. 4, 2011 Palatin Technologies, Inc. (NYSE ... of a Phase 1 clinical trial of AZD2820, a ... a single-agent therapy for the treatment of obesity. AZD2820 ... collaborative research program with Palatin Technologies. Obesity ...
Cached Biology Technology:Designing diamond circuits for extreme environments 2Designing diamond circuits for extreme environments 3Interleukin Genetics, Inc. Announces Conference Call to Discuss Second Quarter 2011 Results 2Palatin Announces Commencement of a Phase 1 Trial for Obesity Compound in Collaboration with AstraZeneca 2Palatin Announces Commencement of a Phase 1 Trial for Obesity Compound in Collaboration with AstraZeneca 3
... high experimental throughput, minimum input of ... 4 up to 16 culture vessels ... users with proven fermentation results when ... fungi or any other microbial application. ...
... If particles in the submicron range are ... process, measurement and control of particle size ... analyzer that can reliably detect the component ... N5 Submicron Particle Size Analyzer uses Photon ...
... of Caspase/DIABLO Liquid. In 100 mM ... CYCLES. Amino acid residues 56 - 239 of ... sequence was expressed in and purified from ... with cytochrome c during apoptosis and ...
... to support the growth of cells derived ... The medium is a modification of Wyatt's ... lines established by Grace using this medium ... basal medium, when properly supplemented, has been ...
Biology Products: