Navigation Links
FDA approves first medical device using rutgers biomaterial

Rutgers scientists and TyRx Pharma, Inc., have announced the Food and Drug Administration's clearance of a new medical device for hernia repair that incorporates a biodegradable technology developed at the university. This action signals a paradigm shift in the application of biomaterials from permanent prosthetic replacements toward regenerative medicine, in which materials help the body to repair itself and are then resorbed.

The device consists of a surgical mesh coated with a polymer developed using a Rutgers bioresorbable technology. The polymer gives the surgical mesh improved handling characteristics that facilitate precise placement during the surgical repair and leave less implant material following the resorption of the coating.

Hernias occur when musculature fails and one part of the body protrudes through the resulting gap or opening into another part of the body. And although a hernia can theoretically develop almost anywhere, most are in the groin and abdominal areas.

The partially degradable device has been developed and will be marketed by TyRx Pharma, Inc., a medical device company founded in 1998.

"The company's early research was conducted at the Rutgers-based New Jersey Center for Biomaterials (CBM) in Rutgers' chemistry laboratories," said Joachim Kohn, CBM director and Board of Governors Professor of Chemistry and Chemical Biology at Rutgers, The State University of New Jersey. "This is an example of a close and strong academic-industry interaction that led to a relatively fast entrance of the product into the medical market."

Kohn pointed out that the technology was invented in 1997 and has progressed along a fast and efficient track to FDA approval ?a process that usually takes 10 years or more.

The invention was made with initial research support from the National Institutes of Health and demonstrates how a federal agency's funding can reap benefits for the American public. On a local level, the company and the invention from which it grew have already led to economic benefits for New Jersey through the creation of some 30 new jobs.

"There are only a handful of synthetic, degradable polymers that have an FDA approval history ?therefore, the approval of the TyRx device employing a new biomaterial represents a major breakthrough for regenerative medicine," Kohn said.

The novel tyrosine-based polyarylates, as they are known chemically, arose from an adaptation of combinatorial chemistry to biomaterials. "Our approach uses two sets of starting materials that are combined with each other in all possible combinations," Kohn said. "In this way, we can create a large variety of related polymers from a small number of initial starting materials."

The result in this case was a library of 112 structurally related materials created in parallel, each one potentially useful in a wide range of medical implant applications. TyRx has licensed this entire library of polyarylates from Rutgers and has now, as a first application, identified one of these polymers for the hernia repair device.

The New Jersey Center for Biomaterials, based at Rutgers, is a cooperative research initiative sponsored by Rutgers, the University of Medicine and Dentistry of New Jersey and New Jersey Institute of Technology.

Established in 1766, Rutgers is America's eighth oldest institution of higher learning and one of the nation's premier public research universities.

TyRx Pharma, Inc. designs, develops and commercializes innovative combination medical devices and drug delivery products using patent protected tyrosine-derived polyarylates.


'"/>

Source:Rutgers, the State University of New Jersey


Related biology news :

1. Canada approves marijuana-based pain spray
2. FDA approves more generic AIDS drugs
3. FDA approves child-friendly AIDS medicine
4. Health Canada approves cold and flu medicine
5. A genes first kiss sets off that affair known as puberty
6. Love at first smell
7. Worlds largest rainforest drying experiment completes first phase
8. PCRM develops worlds first cruelty-free insulin assay
9. Expression Project for Oncology (expO) completes first phase of standardized gene expression analyses
10. World-first Living Donor Islet Cell Transplant A Success; Procedure Offers Promise For Diabetics
11. DuPonts first biologically derived polymer receives global recognition
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/28/2017)... February 28, 2017 News solutions for biometrics, ... ... from 14 to 16 March, Materna will present its ... how seamless travel is a real benefit for passengers. To ... to their passenger touch point solutions to take passengers through the ...
(Date:2/27/2017)... --  Strategic Cyber Ventures , the industry,s first cybersecurity ... million investment in  Polarity , the first commercial human ... based and is led by cybersecurity veterans Tom ... Gula , also a longtime cybersecurity veteran and founder ... A round of funding. This new funding will be ...
(Date:2/24/2017)... , Feb. 24, 2017  EyeLock LLC, a leader of ... elite iris biometric solution on the latest Qualcomm® ... at Mobile World Congress 2017 (February 27 ... in Hall 3, Stand 3E10. ... Haven™ security platform—a combination of hardware, software ...
Breaking Biology News(10 mins):
(Date:3/27/2017)... ... March 27, 2017 , ... IsoPlexis Corporation (IsoPlexis), a venture ... and more through a single-cell precision engineering platform, today announced it has received ... in the laboratory of Dr. James Heath at the California Institute of Technology, ...
(Date:3/27/2017)... Linda, Ca (PRWEB) , ... March 27, 2017 ... ... metastatic colorectal cancer (mCRC) generally produce small, heterogeneous samples with limited tumor content ... analytical challenges remain to be resolved, such as the need for reliable detection ...
(Date:3/27/2017)... 27, 2017  The global market for clinical ... to a new report from Kalorama Information.  In ... performed to evaluate disease progression, monitor drug treatment ... reasons.  The healthcare market research firm,s report, ... an overview of the medical laboratory industry and ...
(Date:3/27/2017)... , March 27, 2017 The new ... a comprehensive library of reports on Valero Energy , ... fuels and petrochemical industries. ...      (Logo: http://photos.prnewswire.com/prnh/20160330/349511LOGO) ... production to go green. Ethanol today, even though touted as ...
Breaking Biology Technology: