Navigation Links
Expression Project for Oncology (expO) completes first phase of standardized gene expression analyses

course of 3 years.

Standardization of the collection, analysis, and vocabularies will help accelerate future development of new, targeted cancer treatments. Standardization, which will take place at every phase from consent to collection to gene expression, will result in better patient care.

Collaboration with the participating medical centers in the mechanics of tumor collection has also improved the quality of the collected tissues. The collection of tumor samples from surgery is historically difficult to achieve rapidly, due to the number of handling and review steps required to insure that the release of that tumor sample in no way jeopardizes patient care. Nonetheless, rapid handling is a necessity in order to maintain the integrity of RNA by quickly freezing the portion of tumor released for analysis. Historically, collection efforts typically achieve a successful preservation rate of 75%. Due to close collaboration between the surgeons, pathologists, local clinical research coordinators and expO, the success rate achieved in preserving these samples was 100%. Such well-preserved tissue allows the subsequent analysis to more precisely reflect the tumor’s biology.

"We are very pleased with the significant successes the project has achieved in our first year,"?said Robert Penny, M.D., Ph.D, Executive Director of expO and Chief Medical Officer of IGC. "These findings will be of benefit to the worldwide research community."

Consortium funding for expO’s launch comes from six international pharmaceutical firms. Major sponsors are Bristol-Myers Squibb, GlaxoSmithKline, Wyeth and IBM. Other sponsors are Pfizer, Aventis,

Johnson & Johnson, Flinn Foundation, ILEX Oncology, and Genomics Collaborative Inc. Research support from Affymetrix, AmeriPath, the Georgia Cancer Coalition, Agilent Technologies, Amersham Biosciences, and Telik Inc. also springboards the effort.

Major founding support was provided to IGC from Ari
'"/>

Source:International Genomics Consortium


Page: 1 2 3

Related biology news :

1. Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible
2. Iron Deficiency Sparks Dramatic Changes In Gene Expression
3. Applied Biosystems Introduces Advanced Gene Expression Service Provider Program
4. Gene Expression in the Aging Brain
5. The Shapes Of Life: NIGMS Project Yields More Than 1,000 Protein Structures
6. Whole genome promoter mapping - Human Genome Project v2.0?
7. Knockout Mouse Project
8. Worlds largest rainforest drying experiment completes first phase
9. Sandia completes depleted uranium study
10. LIAI completes worlds most comprehensive analysis on influenza virus data
11. A genes first kiss sets off that affair known as puberty
Post Your Comments:
(Date:8/27/2014)... Dinosaurs are often depicted as giant, frightening beasts. But ... examination of a rock slab containing fossils of 24 ... of a group of hatchlings overseen by a caretaker, ... researchers. , Penn,s Brandon P. Hedrick and Peter Dodson ... Museum of Natural History, where the specimen is held. ...
(Date:8/27/2014)... that a deficiency in serotonin a chemical messenger ... depression. In the journal ACS Chemical Neuroscience , ... serotonin in their brains (and thus should have been ... , Donald Kuhn and colleagues at the John ... School of Medicine note that depression poses a major ...
(Date:8/27/2014)... growing number of studies have shown that ... pathogenesis of Parkinson,s disease. Previous studies from ... University in China have shown that baicalin ... reduced divalent metal transporter 1 expression, and ... nigra of rotenone-induced Parkinson,s disease rats. However, ...
Breaking Biology News(10 mins):Penn paleontologists describe a possible dinosaur nest and young 'babysitter' 2Penn paleontologists describe a possible dinosaur nest and young 'babysitter' 3New study throws into question long-held belief about depression 2
... The bubbles in your champagne that appear to jump out ... quite similar to the tiny bubbles found throughout the world,s oceans, ... the champagne bubbles are likely to raise your spirits, those in ... "Bubbles are little packets of gases that rise or fall ...
... in the American diet by as little as one-half teaspoon ... attacks and 92,000 deaths each year, according to a new ... from reductions in smoking and could save the United States ... A team from the University of California, San Francisco, ...
... PHILADELPHIA - Biologists at the University of Pennsylvania studying ... longstanding conundrum: How can organisms be robust against the ... changes? The short answer, according to University ... two requirements are often not contradictory and that an ...
Cached Biology News:Bubble physicist counts bubbles in the ocean to answer questions about climate, sound, light 2Bubble physicist counts bubbles in the ocean to answer questions about climate, sound, light 3Even small dietary reductions in salt could mean fewer heart attacks, strokes and deaths 2Even small dietary reductions in salt could mean fewer heart attacks, strokes and deaths 3Penn biologists explain how organisms can tolerate mutations, yet adapt to environmental change 2
(Date:8/27/2014)... 27, 2014 In 2013, ... Lawrence Livermore National Security LLC (LLNS), was ... deliver a state-of-the-art laser system for the European ... under construction in the Czech Republic. , When ... system, called the " High repetition-rate Advanced Petawatt ...
(Date:8/27/2014)... survive impact by the huge amounts of energy ... energy for photosynthesis. The hypothesis is that the ... the energy throughout the entire protein molecule through ... now managed to successfully ,film, this process. , ... which play a role in photosynthesis and thus ...
(Date:8/27/2014)... , Aug. 27, 2014 ... the "Global Lactic Acid  (Biodegradable Polymer, Food ... Trends & Forecasts to 2019" report to ... simplest hydroxyl-carboxylic acid with an asymmetrical carbon atom. ... the biodegradable polymer, food and beverage, personal care ...
(Date:8/27/2014)... 2014 “We are honored to be ... Ven Thangaraj, CEO of Radiant Sage. “We are offering ... the imaging corelab market to a different level. ... organizations to efficiently and effectively manage the massive amounts ... be analyzed and read by trained physicians. Being recognized ...
Breaking Biology Technology:LLNL Synchs up with ELI Beamlines on Timing System 2LLNL Synchs up with ELI Beamlines on Timing System 3DTU researchers film protein quake for the first time 2Global Lactic Acid (Biodegradable Polymer, Food & Beverage, Personal Care & Pharmaceutical) Market - Trends & Forecasts to 2019 2Radiant Sage Named to CIOReview List of 100 Most Promising Technology Companies 2
... More Effective Than rituximab ... in a Pre-Clinical ... announced today that ofatumumab (HuMax-CD20(R)) appeared more,effective at inducing complement ... a pre-clinical study. The CD20,antibodies were incubated with tumor cells ...
... YORK, Sept. 6 Globally, approximately 418 million,people ... danger, and costs of hepatitis in the 21st ... Hepatitis Strategies, a,new report by Kalorama Information. ... not,taking the necessary steps to contain hepatitis. Yet ...
... Globally, approximately 418 billion,people are currently infected with ... hepatitis in the 21st century cannot be,understated or ... by Kalorama Information. Paradoxically, despite the obvious ... to contain hepatitis. Yet the incidence and,prevalence of ...
Cached Biology Technology:Genmab Announces Encouraging Preclinical Data for ofatumumab 2Touching 418 Million Lives, Hepatitis Still Presents Significant Threat to Global Health 2Touching 418 Billion Lives, Hepatitis Still Presents Significant Threat to Global Health 2
MOUSE ANTI GTP BINDING PROTEIN...
... of the human Topoisomerase II gene. ... state of nucleic acids by passing an intact ... a separate DNA helix (1,2) . As a ... enzyme can relax negatively or positively supercoiled DNA, ...
... Cell Expansion Kit - Monolayer is a system ... as a monolayer in a serum-free environment. The ... Supplement, which has been optimized for neural stem ... (1996) Genes & Development 10 :3129). Human ...
... Reverse Transcriptase (AMV RT) catalyzes the polymerization ... RNA:DNA hybrids (1). It requires a primer ... primers) as well as Mg2+ or Mn2+. ... activity. Both nonionic detergents and sulfhydryl compounds ...
Biology Products: