Navigation Links
Exploring the dark matter of the genome

latively easy to perform in euchromatin but harder in heterochromatin, "because it is so rich in repeats."

Smith and his colleagues found evidence for 230 to 254 protein-coding genes in the heterochromatin, previously thought to contain a mere 30 to 40 (the fly's total is 14,000 or more). Many of these genes were organized quite differently from genes in euchromatin, with much longer gaps (introns) between the coding sections of the gene (exons); unlike the introns in euchromatic genes, these long gaps consisted almost entirely of repeating sequences derived from disabled transposons. The evidence suggests that heterochromatic genes are regulated differently from euchromatic ones.

Besides protein-coding genes, the annotators found other significant elements in the heterochromatin, including 13 single-copy genes that do not code for proteins but for small RNA structures called noncoding RNAs.

They also found pseudogenes -- truncated copies of genes which have become inactive, most likely because they have been duplicated or code for traits no longer needed by the organism. Drosophila has very few pseudogenes compared to most complex organisms (humans have some 20,000), but the annotators found 32 new ones in the heterochromatin, more than twice as many as previously described.

Finally, the annotators calculated the kind and distribution of repeating elements. "The heterochromatin is incredibly repeat-rich," says Smith, "and most of it is transposable elements that have been chewed up and fragmented."

Susan Celniker emphasizes that transposable elements, of which 96 families have been found in Drosophila so far, "can be very dangerous. They are viruses -- literally." She points out that during subsequent sequencing efforts, DNA was made three times from the same strain of flies -- in 1990, 1998, and 1999 -- and that new patterns of transposons were found in each. "We can see intact transposons moving from one posi
'"/>

Source:DOE/Lawrence Berkeley National Laboratory


Page: 1 2 3 4 5 6

Related biology news :

1. Exploring the molecular origin of blood clot flexibility
2. To sea or not to sea: When it comes to salmon sex, size sometimes doesnt matter
3. Size matters: Preventing large mammal extinction
4. Space matters: Estimating species diversity in the fossil record
5. Looks matter to female barn swallows
6. Bigger brain size matters for intellectual ability
7. UCSB researchers discover shape matters to macrophages
8. Researchers find that bumblebees flower choice matters
9. For Pacific white shrimp, gender matters when competing for food
10. Particle size matters to bacteria ability to immobilize heavy metals
11. Monitoring poisons in the environment -- a woolly matter
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Exploring the dark matter the genome

(Date:7/30/2014)... as simple as inserting a medicated, disappearing fabric minutes ... have discovered a potentially faster way to deliver a ... method spins the drug into silk-like fibers that quickly ... of the drug than possible with other topical materials ... women a potentially more effective, discreet way to protect ...
(Date:7/30/2014)... out how to create colors, nature had already perfected ... many different hues, for example. Now scientists are tapping ... way to make colored plastics. Their paper on using ... rather than dyes, to produce color appears in ... Asger Mortensen, Anders Kristensen and colleagues point out that ...
(Date:7/30/2014)... University Professor Steven Chown has been awarded the ... for Excellence in Antarctic Research. , SCAR, an ... high quality international scientific research in the Antarctic ... region in the Earth system. The organisation also ... Treaty System, responsible for governing the region. , ...
Breaking Biology News(10 mins):Dissolvable fabric loaded with medicine might offer faster protection against HIV 2Dissolvable fabric loaded with medicine might offer faster protection against HIV 3
... Mitochondrial diseases disrupt the power generating machinery within cells ... in the lungs or respiratory tract. A new study ... shows that infection with the pneumonia causing bacteria ... a signaling protein that is associated with mitochondrial disease. ...
... Stony Brook, N.Y., July 27, 2009 - Temperature ... amphibians, crustaceans, and lizards live longer at higher latitudes ... week in the Proceedings of the National Academy ... Dr. Stephan Munch and Ph.D. candidate Santiago Salinas, both ...
... Los Angeles, London, New Delhi, Singapore and Washington DC ... special issue of Medical Decision Making , a ... overwhelm hospital resources even with an extremely effective public ... the attack and initiating a response to it. ...
Cached Biology News:Stress signals link pre-existing sickness with susceptibility to bacterial infection 2Warmer environment means shorter lives for cold-blooded animals 2Bioterrorism and disaster preparedness explored in special issue of Medical Decision Making 2
(Date:7/30/2014)... July 30, 2014  RXi Pharmaceuticals Corporation ... company focused on discovering, developing and commercializing ... using RNA-targeted technologies, today announced that their ... for the reduction of recurrence of hypertrophic ... been initiated. Logo - ...
(Date:7/30/2014)... Henderson, CA (PRWEB) July 30, 2014 ... hosting presentations of leading Immunologists, Principle Investigators, scientists ... Charles J Malemud, Professor at Case Western ... be delivering his keynote address on “The ... TNF-a in production of matrix metalloproteinase-9”. Arya Biragyn, ...
(Date:7/29/2014)... July 29, 2014 The advanced optical ... brain that are driving a revolution in the neurosciences ... peer-reviewed journal published by SPIE, the international society ... coincides with the launch of the BRAIN Initiative in ... that lay out a vision for and provide examples ...
(Date:7/29/2014)... A team of researchers has created a new ... three-dimensional textures. These surfaces, made by self-assembly of ... properties including controllable mechanical stiffness and strength, ... certain direction. , "We have demonstrated that mechanical ... form complex three-dimensional microstructures, and that we can ...
Breaking Biology Technology:RXi Pharmaceuticals Expands Clinical Program with Initiation of Third Phase 2a Study with RXI-109 for Treatment of Hypertrophic Scars 2RXi Pharmaceuticals Expands Clinical Program with Initiation of Third Phase 2a Study with RXI-109 for Treatment of Hypertrophic Scars 3RXi Pharmaceuticals Expands Clinical Program with Initiation of Third Phase 2a Study with RXI-109 for Treatment of Hypertrophic Scars 4RXi Pharmaceuticals Expands Clinical Program with Initiation of Third Phase 2a Study with RXI-109 for Treatment of Hypertrophic Scars 5Unveiling Breakthroughs in Clinical & Cellular Immunology 2Unveiling Breakthroughs in Clinical & Cellular Immunology 3SPIE Launches 'Neurophotonics' Journal with Special Section on BRAIN Initiative 2SPIE Launches 'Neurophotonics' Journal with Special Section on BRAIN Initiative 3SPIE Launches 'Neurophotonics' Journal with Special Section on BRAIN Initiative 4A new way to make microstructured surfaces 2
... Korea, August 8, 2011Can a flexible LED conformably placed on ... human brain, or rolled upon the blood vessels, diagnose or ... in the near future. The team of Professor Keon ... developed a new concept: a biocompatible, flexible Gallium Nitride (GaN) ...
... (OTCBB: IAGX) announced today that it received an adverse ... its pending dispute with former distributor TriPharma, LLC and ... a private arbitrator and is conducted under the rules ... Diego, California.  The interim award against the Company and ...
... Sept. 19, 2011 Reportlinker.com announces that ... in its catalogue: Established ... http://www.reportlinker.com/p0618133/Established-and-Emerging-Biotech-Clusters.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Biotechnology There ... focused clusters of biotechnology companies and related ...
Cached Biology Technology:Established and Emerging Biotech Clusters 2Established and Emerging Biotech Clusters 3Established and Emerging Biotech Clusters 4Established and Emerging Biotech Clusters 5Established and Emerging Biotech Clusters 6Established and Emerging Biotech Clusters 7Established and Emerging Biotech Clusters 8
... causing shortages in your laboratory or fellow ... cause unwanted distractions, problems and delays. • ... hard work and endeavour! Bring us your ... and market it internationally. We work under ...
... Perhaps sheer in-house demand is causing shortages ... precious antibody. This can cause unwanted distractions, ... Receive royalties for your hard work ... let us build it up,and market it ...
Topoisomerase I...
...
Biology Products: