Navigation Links
Experimental vaccine protects mice against deadly 1918 flu virus

Federal scientists have developed a vaccine that protects mice against the killer 1918 influenza virus. They also have created a technique for identifying antibodies that neutralize this virus, a tool that could help contain future pandemic flu strains. These findings are important, the researchers say, to understanding and preventing the recurrence of the H1N1 influenza virus that caused the 1918 pandemic and to protecting against virulent flu strains in the future, including the H5N1 avian flu virus. Details of the research are available online this week in Proceedings of the National Academy of Sciences.

Gary J. Nabel, M.D., Ph.D., director of the Vaccine Research Center (VRC) at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), led the research team in developing the experimental vaccines and conducting the immunological studies in mice. Terrence Tumpey, Ph.D., of the Centers for Disease Control and Prevention (CDC) conducted vaccine studies in mice involving the live, reconstructed 1918 flu virus in a biosafety level 3-enhanced laboratory at the CDC in Atlanta--one of four types of specialized biosafety labs where scientists study contagious and potentially deadly materials under high-level safety and contamination precautions designed to protect the researchers and prevent microorganisms from entering the environment.

"Understanding why this influenza virus was so deadly is an extremely important question," says NIAID Director Anthony S. Fauci, M.D. "By building upon earlier research where scientists successfully reconstructed the 1918 pandemic flu strain, Dr. Nabel and his colleagues have demonstrated that this virus is vulnerable to intervention. This knowledge will help further our continued efforts to develop treatments and vaccines to protect us against another deadly flu pandemic."

The 1918-1919 influenza pandemic was the most deadly flu outbreak in modern histor
'"/>

Source:NIH/National Institute of Allergy and Infectious Diseases


Page: 1 2 3 4

Related biology news :

1. NIAID Initiates Trial of Experimental Avian Flu Vaccine
2. Experimental shingles vaccine proves effective in nationwide study
3. Experimental vaccine protects nonhuman primates when given after exposure to Marburg virus
4. Experimental TB drug effective against resistant and latent mycobacterium tuberculosis
5. Experimental drug reverses key cognitive deficits, pathology in Alzheimers
6. Experimental RNA-based drug kills prostate cancer cells effectively and safely
7. Experimental vaccine protects lab animals against several strains of H5N1
8. Experimental cancer drugs counter muscle deterioration seen in muscular dystrophy
9. Experimental vaccine given during pregnancy reduces stillbirths from common virus
10. Research advances quest for HIV-1 vaccine
11. A much-needed shot in the arm for HIV vaccine development
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Experimental vaccine protects mice against deadly flu virus

(Date:5/23/2013)... Science , Automated conserved noncoding ... promoter evolution among grasses , Within the genome ... DNA that undergo little change in position and sequence ... any proteins. Some of these evolutionarily stable sequences, so-called ... expression of other genes or the condensation of chromosomes, ...
(Date:5/23/2013)... Health at Emory University, along with partners at ... $4 million grant over four years to establish ... Exposome Research Center: Understanding Lifetime Exposures). The grant ... the United States. , The HERCULES Center ... Health Sciences (NIEHS) of the National Institutes of ...
(Date:5/23/2013)... undergo surgery or harsh treatments because science fails ... forms of the disease. Researchers at Case Western ... developing technology that allows patients to safely choose ... or take drastic measures. , The project is ... of biomedical engineering at Case Western Reserve and ...
Breaking Biology News(10 mins):Frontiers news briefs: May 23 2Frontiers news briefs: May 23 3Emory, Georgia Tech receive first human exposome center grant in US 2Emory, Georgia Tech receive first human exposome center grant in US 3Using big data to identify prostate cancers and best treatments 2Using big data to identify prostate cancers and best treatments 3
... reporting new evidence that certain high blood pressure drugs may ... cause of vision loss in people with diabetes. The study, ... lead to new ways to prevent or treat the sight-threatening ... of Proteome Research , a monthly publication. Edward ...
... are embracing new tactics to deal with an estimated ... from being won. That,s the focus of an article ... News (C&EN) , ACS, weekly newsmagazine. Counterfeiting ploys include ... identify their products as genuine. C&EN Associate Editor ...
... shown that it is not, as has long been presumed, to ... Biomechanics, who have modelled the cohesive strength of food after a ... food to ensure it is in a firm blob and, therefore, ... Dr Roland Ennos, a biomechanic in the Faculty of Life Sciences ...
Cached Biology News:How people work ... and the fingerprint mystery 2
(Date:5/23/2013)... (PRWEB) May 23, 2013 Patheon ... manufacturing services to the global pharmaceutical industry, will host ... Novel Approaches to Testing” on Tuesday, June 4, 2013 ... pharmaceutical manufacturers are required to comply with regulations for ... practices with limited scientific underpinning and little evaluation of ...
(Date:5/23/2013)... 23, 2013 PI’s new LPS-24 ... provide 15 mm travel range with closed-loop sensor ... dimensions make these new positioners the ideal choice ... vacuum rated version is also available. , ... datasheets can be found at: , http://www.physikinstrumente.com/en/products/prdetail.php?sortnr=1000745&prw-lps24 ...
(Date:5/23/2013)... 23, 2013 BioTrends Research Group, one ... for specialized biopharmaceutical issues, finds that, unaided, one ... specialists reported that in the past six months, ... treatment) in anticipation of the next generation of ... when only 6 percent reported that they had ...
(Date:5/23/2013)... May 23, 2013 The New Jersey ... industries, Black Data Processing Associates (BDPA), is hosting its ... 8, 2013. This all-day event will encourage students and ... the ins and outs from many of the industries’ ... at the New Jersey Institute of Technology, the event ...
Breaking Biology Technology:Patheon to Present on “Cleaning Validation: Science, Risk and Novel Approaches to Testing” 2Precision Positioning System Uses Miniaturezed Piezo Linear Motor: LPS-24 Linear Stage by PI 2The Majority of Physicians that Treat Hepatitis C Virus (HCV) Have Begun "Warehousing" and Preparing Their HCV Patients for the Next Generation of HCV Treatments 2The Majority of Physicians that Treat Hepatitis C Virus (HCV) Have Begun "Warehousing" and Preparing Their HCV Patients for the Next Generation of HCV Treatments 3Black Data Processing Associates (BDPA) New Jersey Hosts 10th Annual Families in Technology Day June 8, 2013 2
... tactics. However, there is one area where I finally decided it's ... sure, there are various articles and such that describe the "improved ... The problem is that at least half of us use no ... to prove my point. I took my laptop home from work, ...
... colony of human embryonic stem cells grown over a period ... feeder cells. The cell nuclei are stained green; the cell ... Madison, Wis. Tackling a pressing and controversial ... Research Institute and the University of Wisconsin-Madison have crafted a ...
... duking it out with Los Angeles for second place in ... Chicago's business community is finite. , ,In Milwaukee and throughout ... therefore follows that the technology business community is even smaller. ... curse. , ,One of the inevitable outcomes of spending some ...
Cached Biology Technology:Screen-door security: most wireless networks left wide open 2Screen-door security: most wireless networks left wide open 3Human stem cells stand on their own 2Human stem cells stand on their own 3How name-dropping can make interviews fail 2How name-dropping can make interviews fail 3How name-dropping can make interviews fail 4