Navigation Links
Experimental vaccine given during pregnancy reduces stillbirths from common virus

tal amount of virus found in the mothers?blood. The vaccine in the study was developed in collaboration with researchers at AlphaVax, Inc.

Background

CMV is a common viral infection related to the herpes virus and often causes few or no symptoms, according to the National Institute on Deafness and Other Communication Disorders. Every year, 0.5 to 2.5 percent of babies born in the United States are infected with CMV. The virus is transmitted to the fetus through the mother’s placenta.

Dr. Schleiss said that 10 percent to 15 percent of babies with congenital CMV have a long-term disability such as mental retardation, cerebral palsy, and hearing loss. The infection could potentially cause other developmental disabilities such as autism or attention deficit disorder. The virus can also damage the placenta, leading to pregnancy loss.

CMV is present in bodily secretions and is spread through close personal contact, such as kissing or sharing eating utensils. For example, an infant in daycare could give the virus to her pregnant mother by kissing her on the lips, said Dr. Schleiss. The virus can enter through mucosal surfaces such as the mouth or breaks in the skin. It can also be transmitted through nasal secretions, blood transfusions, and sexual contact. Most adults will become infected with CMV at some point during their lives. Dr. Schleiss added that pregnant women may not even know they have the infection.

CMV Vaccine Prototype

The experimental vaccine differs from traditional vaccines, which are made from a whole killed virus. Called a vector vaccine, the experimental vaccine uses an altered virus to deliver one gene from the viral DNA to the animal’s cells. The cells then begin manufacturing the viral protein. Cells of the guinea pigs?immune system detect the viral protein and launch an attack against it. In so doing, they learn to recognize CMV. The gene used in the experime
'"/>

Source:NIH/National Institute of Child Health and Human Development


Page: 1 2 3

Related biology news :

1. NIAID Initiates Trial of Experimental Avian Flu Vaccine
2. Experimental shingles vaccine proves effective in nationwide study
3. Experimental vaccine protects nonhuman primates when given after exposure to Marburg virus
4. Experimental TB drug effective against resistant and latent mycobacterium tuberculosis
5. Experimental drug reverses key cognitive deficits, pathology in Alzheimers
6. Experimental RNA-based drug kills prostate cancer cells effectively and safely
7. Experimental vaccine protects lab animals against several strains of H5N1
8. Experimental vaccine protects mice against deadly 1918 flu virus
9. Experimental cancer drugs counter muscle deterioration seen in muscular dystrophy
10. Research advances quest for HIV-1 vaccine
11. A much-needed shot in the arm for HIV vaccine development
Post Your Comments:
(Date:7/29/2014)... news for parents of preterm babies latest research from ... time they become teenagers, the brains of many preterm children ... , A study conducted by the University,s Robinson Research ... child experiences no brain injury in early life, their cognitive ... their term-born peers. , However, the results of the study, ...
(Date:7/29/2014)... types of cell, including sperm, bacteria and algae, ... These protrusions, about one-hundredth of a millimetre long, ... fluid. Similar, shorter structures called cilia are found ... perform roles such as moving liquids over the ... versatile: they transport mucus and expel pathogens from ...
(Date:7/28/2014)... discovery of two additional coral communities showing signs of damage ... of the 2010 spill in the Gulf of Mexico. The ... professor of biology at Penn State University. A paper describing ... in the Gulf of Mexico will be published during the ... of the journal Proceedings of the National Academy of ...
Breaking Biology News(10 mins):Preterm children's brains can catch up years later 2Microscopic rowing -- without a cox 2Microscopic rowing -- without a cox 3Impact of Deepwater Horizon oil spill on coral is deeper and broader than predicted 2
... genome consortium, consisted of scientists from China Agricultural University, ... the genome sequencing and analysis of the duck ( ... A viruses, which caused a new epidemic in China ... and provides an invaluable resource for unraveling the interactive ...
... Paris, France: French scientists have discovered that supposedly rare ... cells responsible for creating energy, account for more than ... as a respiratory deficiency. Their data emphasise ... DNA (mtDNA) in patients suspected as having a mitochondrial ...
... genetically modified (GM) cotton has significantly improved calorie consumption ... a 7-year-period, according to research published June 5 in ... Matin Qaim and Shahzad Kouser from the University of ... a survey of over 500 randomly selected small farm ...
Cached Biology News:The duck genome provides new insight into fighting bird flu 2Rare mitochondrial mutations -- maybe not so rare? 2
(Date:7/29/2014)... JOLLA, Calif. , July 29, 2014 ... diagnostic and therapeutic company focused on extending the healthy, ... hired Franz Och , Ph.D., an expert in ... Data Scientist. Och comes to HLI from Google where ... Google Translate. He will report directly to HLI Co-Founder ...
(Date:7/29/2014)... 2014) Tough, ultralight foam of atom-thick sheets can ... chemical process invented at Rice University. , In ... nanoscale building, with floors and walls that reinforce each ... materials: floors and walls of graphene oxide that self-assemble ... , The researchers say the foam could find use ...
(Date:7/29/2014)... , July 29, 2014  The Society ... new and updated program for the 9 th ... 12, 2014 in Amelia Island , Florida.  ... and investigators remains unchanged, however, the topics and ... and networking opportunity among all stakeholders with a ...
(Date:7/29/2014)... Second generation biofuels are a viable solution to the ... natural gas is very cheap, this is affecting the biofuels ... as they could be in comparison to natural gas. ... it difficult for renewable energy developers to get the economics ... these reasons, certain companies have shifted their focused within renewable ...
Breaking Biology Technology:Franz Och, Ph.D., Expert in Machine Learning and Machine Translation, Joins Human Longevity, Inc. as Chief Data Scientist 2Franz Och, Ph.D., Expert in Machine Learning and Machine Translation, Joins Human Longevity, Inc. as Chief Data Scientist 3Tough foam from tiny sheets 2TransCelerate, Lilly, Pfizer, and FDA Highlight Collaborative Program at the Site Solutions Summit 2TransCelerate, Lilly, Pfizer, and FDA Highlight Collaborative Program at the Site Solutions Summit 3Renewable Waste Intelligence: Could Renewable Chemicals Be the Future for the Renewable Energy Industry? 2
... historians, journalists and politicians, and has been recounted everywhere from ... forces used chemical weapons on Iraqis just after World War ... squared with the historical record, says R. M. Douglas, a ... the December issue of The Journal of Modern History ...
... at the University of East Anglia (UEA) could contribute ... agricultural waste to generate clean electricity. Published today ... National Academy of Sciences (PNAS), the researchers have ... some bacteria survive by ,breathing rocks,. The findings ...
... roadside bombs to freeway crashes. Traumatic injury, the leading cause ... the body,s natural blood-clotting process. In an effort to ... a new Case Western Reserve University biomedical engineering professor, and ... that show promise in halting internal and external bleeding. Their ...
Cached Biology Technology:Despite claims, UK did not gas Iraqis in the 1920s, new research finds 2Despite claims, UK did not gas Iraqis in the 1920s, new research finds 3Despite claims, UK did not gas Iraqis in the 1920s, new research finds 4'Rock-breathing' bacteria could generate electricity and clean up oil spills 2Researchers take the inside route to halt bleeding 2
... polyclonal to Endothelin B Receptor Like ... Receptor-Like Protein 2 (ETBR-LP-2) has been ... been isolated from human brain and ... Synthetic peptide (unfortunately, the amino acid ...
HSV-2 gD (0191)...
... The epitope recognized by ... of isoform 5 of human ... AAH19917.1 (GeneID 9444). The ... isoforms 1, 2, 3, 4, ...
... The product contains 5 ml Dynabeads Epoxy ... glycidyl ether (epoxy) reactive groups. Ideal for ... are absorbed hydrophobically on initial coupling with ... 2 and sulphydryll groups (SH)) occurring ...
Biology Products: