Navigation Links
Engineers improve plastic's potential for use in implants by linking it to biological material

Engineers at The University of Texas at Austin have found a way to modify a plastic to anchor molecules that promote nerve regeneration, blood vessel growth or other biological processes.

In the study led by Dr. Christine Schmidt, the researchers identified a piece of protein from among a billion candidates that could perform the unusual feat of attaching to polypyrrole, a synthetic polymer (plastic) that conducts electricity and has shown promise in biomedical applications. When the protein piece, or peptide, was linked to a smaller protein piece that human cells like to attach to, polypyrrole gained the ability to attach to cells grown in flasks in the laboratory.

"It will be very useful from a biomedical standpoint to be able to link factors to polypyrrole in the future that stimulate nerve growth or serve other functions," said Schmidt, an associate professor of biomedical engineering at the university.

Schmidt is the principal author for the study conducted with colleague Dr. Angela Belcher at Massachusetts Institute of Technology. It was published online May 15 by the journal Nature Materials.

Polypyrrole is of interest for tissue engineering and other purposes because it is a non-toxic plastic that conducts electricity. As a result, it could be used to extend previous experiments in Schmidt's laboratory. The experiments involve wrapping a tiny strip of plastic around damaged, cable-like extensions of nerve cells called neurites to help them regenerate.

"We can apply an electric field to this synthetic material and enhance neurite repair," said Schmidt. The newly gained ability to attach proteins to polypyrrole, she said, will mean that growth-enhancing factors could also be linked to this plastic wrapping, further stimulating neurite regeneration.

Working with Schmidt and Belcher, the paper's lead authors, graduate students Archit Sanghvi and Kiley Miller identified the peptide that attaches to polypyrrole from a
'"/>

Source:University of Texas at Austin


Page: 1 2 3

Related biology news :

1. Engineers discover why toucan beaks are models of lightweight strength
2. Discovery of key proteins shape could lead to improved bacterial pneumonia vaccine
3. Novel ultrafast laser detection of cancer cells also may improve understanding of stem cells
4. Vascular structure and function improve with diet and exercise
5. Scientists discuss improved biopesticides for locust control in West Africa
6. Product improves peptide identification for proteomics research
7. U. Iowa researchers improve Huntingtons disease symptoms in mice
8. Stem cell treatment improves mobility after spinal cord injury
9. Fragile US vaccine system needs improvement despite dramatic gains in health over past century
10. Monkeying around to improve organ transplantation
11. Research suggests fitness of Florida panthers improved by limited breeding with Texas animals
Post Your Comments:
(Date:2/19/2015)... .19, 2015 Research and Markets ... the "Military Electro-Optical / Infrared Systems Market ... Platform - Forecast to 2020" report to ... systems market is expected to reach $16.35 billion ... This report segments the military electro-optical/infrared ...
(Date:2/11/2015)... , February 11, 2015 ... report "Access Control Market by Product (Cards and Readers, ... Military and Defense, Government, Industrial, Healthcare, Education) and By ... by MarketsandMarkets, the Access Control Market is ... growing at a CAGR of 10.6% between ...
(Date:2/5/2015)... , Jan. 26, 2015   Epic Sciences , ... cancer, today announced that Murali Prahalad , Ph.D., president ... Medicine World Conference (PMWC) 2015: Silicon Valley, which is ... Mountain View, Calif. on January 26-28, 2015. ... Come of Age as Biomarkers." Last year, Epic Sciences was ...
Breaking Biology News(10 mins):Military Electro-Optical / Infrared Systems (Image Intensification, Laser, Infrared) Market - Forecast to 2020: Featuring Profiles of the Market Leaders on this $16 Billion market 2Military Electro-Optical / Infrared Systems (Image Intensification, Laser, Infrared) Market - Forecast to 2020: Featuring Profiles of the Market Leaders on this $16 Billion market 3Access Control Market Worth $10.4 Billion by 2020 2Access Control Market Worth $10.4 Billion by 2020 3Access Control Market Worth $10.4 Billion by 2020 4Epic Sciences to Present at Personalized Medicine World Conference 2015 on the Use of Circulating Tumor Cells as Cancer Biomarkers 2
... molecular events in the origin of fat cells. The ... obesity and diabetes, as fat cells produce hormones critical ... finds that a hormonal cocktail routinely used in the ... from fat-cell precursors to full-blown fat, researchers at University ...
... have used a glowing protein from fireflies to observe ... target for new drugs to treat cancer, autoimmune diseases ... as IKK (for IKappa kinase), regulates processes that can ... these changes to many different disorders. , "Our new ...
... the United States in 2001 the threat of a ... smallpox, plague or tularemia -- became very real. But ... contain an attack is still being developed. , In ... Quantum Devices have demonstrated solar-blind avalanche photodiodes (APDs) that ...
Cached Biology News:Short-term Bio Sensors Monitor From Afar 2Firefly protein lets researchers monitor molecule linked to cancer 2Firefly protein lets researchers monitor molecule linked to cancer 3Tiny avalanche photodiodes target bioterrorism agents 2
(Date:3/5/2015)... and Markets ( http://www.researchandmarkets.com/research/4ld5nw/mature_biotech ) has announced ... New Therapy Ventures Pave the Way for Success" ... companies - Gilead (GILD), Amgen (AMGN), Biogen Idec (BIIB) ... positive return and hence increased the interest of biotech ... indication where the high treatment cost justifies the need. ...
(Date:3/5/2015)... Texas (PRWEB) March 05, 2015 ... of acute and chronic orthopedic conditions such as ... knee, tennis elbow, and joint pain due to ... be administered during orthopedic surgeries to promote better ... scientific advances in nearly pain-free bone marrow harvesting ...
(Date:3/4/2015)... 4, 2015  Brooklyn residents now have a new ... pain and injuries. Nunzio Saulle , M.D., a ... of his NJS Physical Medicine and Rehabilitation (PM&R) practice ... March 5, 2015. Health Plus Management, LLC is managing ... at 1178 Flatbush Avenue. This new PM&R practice will ...
(Date:3/4/2015)... , March 4, 2015 /CNW/ - Resverlogix Corp. ... has completed a collaborative research program with ...  Using Fast Collective Evolution Technology (FACET), Emerald ... all measurements obtained from each of 798 ... 2 clinical trials ASSERT, SUSTAIN and ASSURE. ...
Breaking Biology Technology:Mature Biotech Outlook 2015: New Therapy Ventures Pave the Way for Success 2Mature Biotech Outlook 2015: New Therapy Ventures Pave the Way for Success 3Riordan-McKenna Institute of Regenerative Orthopedics and Stem Cell Therapy Announces Open House in Southlake, Texas on Friday, March 6th from 5:30 pm to 7:30 pm. 2Riordan-McKenna Institute of Regenerative Orthopedics and Stem Cell Therapy Announces Open House in Southlake, Texas on Friday, March 6th from 5:30 pm to 7:30 pm. 3Riordan-McKenna Institute of Regenerative Orthopedics and Stem Cell Therapy Announces Open House in Southlake, Texas on Friday, March 6th from 5:30 pm to 7:30 pm. 4Riordan-McKenna Institute of Regenerative Orthopedics and Stem Cell Therapy Announces Open House in Southlake, Texas on Friday, March 6th from 5:30 pm to 7:30 pm. 5NJS Physical Medicine & Rehabilitation Opening on Flatbush Avenue, Brooklyn, NY 2Resverlogix Collaborates with Emerald Logic to Identify Factors Driving Drug Response and Efficacy in Phase 2 Program 2Resverlogix Collaborates with Emerald Logic to Identify Factors Driving Drug Response and Efficacy in Phase 2 Program 3Resverlogix Collaborates with Emerald Logic to Identify Factors Driving Drug Response and Efficacy in Phase 2 Program 4
... BioCrossroads today announced the receipt of a two-year ... will fund a range of charitable, educational and scientific ... Indiana,s signature strengths in the life sciences. ... 2012, we recognize that Lilly Endowment,s significant investment in ...
... 5, 2011 ZyGEM Corp. Ltd., a developer and ... and other nucleic acids, today announced publication of an ... kit can rapidly extract DNA from small samples of ... produce accurate, reliable and reproducible DNA profiles for forensic ...
... golf clubs, developed by scientists, regularly catch the eye ... McIlroy get excited this time, this new golf putter ... The ,micro putter, developed in a study published today, ... and Technology, has been designed to test the "stickiness" ...
Cached Biology Technology:Two-year $2.8 million Grant from Lilly Endowment Fuels BioCrossroads' Charitable, Educational and Scientific Mission 2Two-year $2.8 million Grant from Lilly Endowment Fuels BioCrossroads' Charitable, Educational and Scientific Mission 3Application Note Shows ZyGEM's forensicGEM® Tissue Facilitates Forensic Casework by Rapidly and Reproducibly Extracting DNA From Human Hair 2Application Note Shows ZyGEM's forensicGEM® Tissue Facilitates Forensic Casework by Rapidly and Reproducibly Extracting DNA From Human Hair 3Scientists take up golf to prove long-standing theory of cell stickiness 2
ACS Reagent Grade C 19 H 14 O 5 S Formula Weight: 354.38 PRODUCT SPECIFICATIONS Form: Rust/red crystalline powder Clarity of Solution: Passes test Visual Transition Interval: pH 6.8 - Yellow pH 8.2...
Mouse monoclonal [34B12] to Nop5p + Nop58p - Nucleolar Marker ( Abpromise for all tested applications)....
... Mouse Anti Nop1p/Fibrillarin (monoclonal) ... nucleolar protein of bakers yeast, Saccharomyces ... is essential for yeast viability and ... human homologue of Nop1p is fibrillarin ...
... A and Protein G bind specifically to ... A and Protein G conjugates are commonly ... (antibodies) and immunoglobulin subtypes from serum, hybridoma ... biological fluids. These reagents are also commonly ...
Biology Products: