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Engineering the heart piece by piece

ster a higher degree of functionality.

Even if cell-growing conditions can be perfected to produce tissue that is strong, durable and shaped like the native tissue it is designed to replace, another major challenge remains: which type of cells to use. Or more clearly, which types of cells to use ?because heart muscle tissue is made up of several types of cells. Human heart cells are hard to come by, and “adult?stem cells haven’t yet been shown to be changeable into cardiac cells. Embryonic stem cells, while promising, come with political baggage. And other types of muscle cells taken from elsewhere in the body ?including skeletal muscles ?have been used in early clinical trials, but results are mixed.
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Source:University of Michigan Health System


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