Navigation Links
Engineered mouse mimics cognitive aspects of schizophrenia

circuits affected in people are more complex than the analogous circuits in rodents. In particular, the relative size of the prefrontal cortex that is involved in the cognitive deficits is much smaller in rodents than in primates. Some of the cognitive symptoms such as hallucinations or delusions are impossible to address.

"However, rodent models have the advantage of allowing direct tests of cause-effect relationships for specific aspects of the disease, such as some of the cognitive deficits," they concluded. "We here have been able to introduce genetically a single molecular alteration in a restricted and regulated fashion and to study its behavioral and physiological consequences."

The researchers said that their findings suggest that cognitive symptoms of schizophrenia may arise from subtle genetic differences in the dopamine receptor gene in schizophrenics that increase receptor activity.


'"/>

Source:Cell Press


Page: 1 2 3

Related biology news :

1. Engineered molecule amplifies bodys immune response
2. Engineered skin offers clues to melanoma development
3. Engineered Stem Cells Show Promise For Sneaking Drugs Into The Brain
4. Engineered heart tissue offers insights into irregular heartbeats, defibrillator failure
5. Engineered yeast speeds ethanol production
6. Man and mouse share genome structures
7. Genome-wide mouse study yields link to human leukemia
8. Report that delayed motherhood decreases life expectancy of mouse offspring
9. Agilent Technologies introduces advanced zebrafish, mouse microarrays for stem cell and developmental biology research
10. Stem cells in bone marrow replenish mouse ovaries
11. Mosaic mouse technique offers a powerful new tool to study diseases and genetics
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Engineered mouse mimics cognitive aspects schizophrenia

(Date:4/15/2014)... associate professor of mechanical engineering at Worcester ... the university,s Integrative Materials Design Center (iMdc), ... from leading engineering societies. , At its ... global association of more than 138,000 engineers ... aerospace, and commercial vehicle industries, presented Lados ...
(Date:4/15/2014)... who study the deadliest infectious diseases recognized the contributions ... at the University of Texas Medical Branch, with a ... on Filoviruses. The filoviruses include Ebola and Marburg viruses ... people infected. The current outbreak of Ebola virus raging ... so far. , "This award represents the culmination ...
(Date:4/15/2014)... Md. (April 15, 2014) The American Association ... award winners. All awards will be presented during ... Diego Marriott Hotel on Tuesday, April 29th at 7:30 ... (EB). , The 2014 award winners are: ... Jeffrey Laitman, PhD, of the Icahn School of Medicine ...
Breaking Biology News(10 mins):WPI's Diana Lados honored by SAE International and Minerals, Metals, and Materials Society 2WPI's Diana Lados honored by SAE International and Minerals, Metals, and Materials Society 3WPI's Diana Lados honored by SAE International and Minerals, Metals, and Materials Society 4WPI's Diana Lados honored by SAE International and Minerals, Metals, and Materials Society 5International research group recognizes UTMB experts 2International research group recognizes UTMB experts 3American Association of Anatomists 2014 award winners 2
... in the Archives of General Psychiatry, researchers at the ... the first time molecular circuitry associated with schizophrenia that ... "This is very exciting because until now the many ... connected in any way," says Akira Sawa, M.D., Ph.D., ...
... color, their knobby knees or their big feet to their children ... through those same genes. New research from the University of ... herpes virus 6 (HHV-6) to their children because it is integrated ... been shown to become part of the human DNA and then ...
... and other hoofed animals, new research suggests that, when ... study, published today in the open access journal ... wolves will reduce deer hunting activity and instead focus ... Victoria and the Raincoast Conservation Foundation, Canada, led a ...
Cached Biology News:Hopkins researchers piece together gene 'network' linked to schizophrenia 2Hopkins researchers piece together gene 'network' linked to schizophrenia 3Virus weaves itself into the DNA transferred from parents to babies 2Wolves would rather eat salmon 2
(Date:1/15/2014)... 2014 The Microcompetition with Foreign DNA ... disease. One of these latent viruses is the Epstein ... rheumatoid arthritis (RA). Rheumatoid arthritis (RA) is a chronic ... by the theory, a study found that RA patients ... (1). , What is Microcompetition? , Dr. Hanan ...
(Date:1/15/2014)... Sunnyvale, CA (PRWEB) January 15, 2014 ... of high throughput research solutions, today announced that ... companies, has received delivery of Freeslate’s CM ... form screening. , Lupin, headquartered in Mumbai, ... quality, affordable generic and branded formulations and Active ...
(Date:1/14/2014)... (PRWEB) January 14, 2014 Date: Friday, ... p.m. , Location: Warrington Country Club, 1360 Almshouse Road, ... Foundation, the only national nonprofit organization solely dedicated to ... quality of life for those affected worldwide, will host ... Warrington Country Club in Warrington, Pa. , Each ...
(Date:1/14/2014)... , Jan. 14, 2014  3D Communications, a leading provider ... major scientific, regulatory, business, and media events in ... , today announced its former associate Virginia Cox , ... office. Virginia Cox re-joins ... Commissioner for the Office of External Affairs at the U.S. ...
Breaking Biology Technology:Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 3Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 2Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 3Hepatitis B Foundation to Host Annual Crystal Ball Gala 2Former FDA Associate Commissioner Returns To 3D Communications 2
... Inc.,(Nasdaq: NVAX ) and the ... a preclinical study of a Respiratory Syncytial Virus ... rights from the, University of Massachusetts Medical School ... of Paramyxovirus vaccines incorporating,certain Virus-Like-Particles ("VLPs"). This ...
... announced as the recipient of a $750,000 investment by the Michigan ... ... Wire EON) December 9, 2008 -- Invest Michigan!, a program ... one of only two companies to receive capital in its first ...
... Dec. 9 First Coast Service Options (FCSO) has ... reimbursement solutions, to support a new Medicare contract awarded ... (CMS). , , Under ... Jan. 1, 2009 between health care providers and organizations ...
Cached Biology Technology:NOVAVAX and the University of Massachusetts Medical School Announce Preclinical Study Results for a Respiratory Syncytial Virus ('RSV') Vaccine Candidate 2NOVAVAX and the University of Massachusetts Medical School Announce Preclinical Study Results for a Respiratory Syncytial Virus ('RSV') Vaccine Candidate 3NOVAVAX and the University of Massachusetts Medical School Announce Preclinical Study Results for a Respiratory Syncytial Virus ('RSV') Vaccine Candidate 4 EcoSphere(R) Biolatex(TM) Secures Funding from Granholm and Invest Michigan! 2FCSO Selects Burgess as Exclusive Pricing Solution for New Medicare Contract 2
... Agencourt offers quick turnaround sequencing of ... copy and high copy plasmids. Agencourt's world-class, ... million Phred20 bases per day. The ... Sequencing service are 24 48 hour ...
Great for biotinylating DNA/RNA probes...
...
...
Biology Products: