Navigation Links
Engineered Stem Cells Show Promise For Sneaking Drugs Into The Brain

to be overcome before such a technique could be attempted in human patients, says Svendsen, is developing a method to switch transplanted cells on or off and thus control their drug delivery capabilities. Working with engineered cells in culture, the Wisconsin group found they could switch the cells on and off using a second drug. Doing so in animal models, however, was more difficult and the issue will need to be addressed in new experiments, according to Svendsen.

The new study, Svendsen argues, proves that progenitor cells -- cells that can now be made in large quantities in the laboratory -- can be crafted to help clinicians deliver drugs where they are needed most in the body. Delivering medicine to the brain, whose blood-brain barrier effectively excludes more than 70 percent of all drugs, would be an especially valuable use for the cells. Such a new method may be useful for treating a number of neurodegenerative diseases beyond Parkinson's, he says.

In addition to Svendsen and Behrstock, authors of the new Gene Therapy paper include Allison Ebert, Jacqueline McHugh, Stephen Vosberg, Elizabeth Capowski, Bernard Schneider and Derek Hei, all of UW-Madison; Jeffery Kordower of Rush University Medical Center; and Patrick Aebischer of the Swiss Federal Institute of Technology.


'"/>

Source:University of Wisconsin-Madison


Page: 1 2 3

Related biology news :

1. Engineered molecule amplifies bodys immune response
2. Engineered skin offers clues to melanoma development
3. Engineered mouse mimics cognitive aspects of schizophrenia
4. Engineered heart tissue offers insights into irregular heartbeats, defibrillator failure
5. Engineered yeast speeds ethanol production
6. Jump-starting T Cells In Skin Cancer
7. Emory Study Tests Bone Marrow Stem Cells to Improve Circulation in Legs
8. Transplantation Of Monkey Embryonic Stem Cells Reverses Parkinson Disease In Primates
9. Fundamental Finding Yields Insight into Stem Cells, Cancer; Opens Door to Drug Discovery
10. Weill Cornell Research Reveals Secrets Of Trafficking Within Cells
11. First-ever Compounds To Target Only Metastatic Cells Are Highly Effective Against Breast, Prostate, And Colon Cancers
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Engineered Stem Cells Show Promise For Sneaking Drugs Into The Brain

(Date:12/4/2014)... BEACH GARDENS, Fla. , Dec. 3, 2014 ... management solutions, today announced that its DigitalPersona ® ... 4500 fingerprint readers have been deployed throughout First ... , South Carolina ... headquartered in Southern Pines, North Carolina ...
(Date:11/21/2014)... -- According to a new market research ... Access Control, Intrusion Detection, Parking Management, Under Vehicle Inspection), ... Geography - Global Forecasts to 2020", published by MarketsandMarkets, ... around $25 Billion in 2014 and is expected to ... of 8.69%. Browse 116 market data Tables ...
(Date:11/21/2014)... -- C-Labs LLC, a leading provider of remote and ... announced the appointment of John Traynor to ... advisor to the firm, Mr. Traynor will now oversee ... out of the C-Labs office in Redmond, ... , Chief Executive Officer. Photo - ...
Breaking Biology News(10 mins):First Bank Partners with Crossmatch to Increase Log In Security 2First Bank Partners with Crossmatch to Increase Log In Security 3Industrial Security Systems Market Worth $38 Billion by 2020 2Industrial Security Systems Market Worth $38 Billion by 2020 3C-Labs Names Former Microsoft and Bsquare Executive as Chief Operating Officer 2
... 2011 In a new study scientists at NYU Langone ... be improved. The new findings, published online November 20, 2011, ... the loss of smell due to aging or disease. ... A. Wilson, PhD, professor of child and adolescent psychiatry at ...
... University of British Columbia researchers reveals how the effect of ... fisheries practices. "Fisheries are already providing fewer fish and ... says Rashid Sumaila, principal investigator of the Fisheries Economics Research ... "We could be earning interest, but instead we,re fishing away ...
... Suitable habitat for native fishes in many Great Plains ... from the High Plains aquifer and scientists analyzing the ... Results of their study have been published in the ... be replenished seasonally with rain and snow, these regional aquifers ...
Cached Biology News:A failing sense of smell can be reversed 2Effects of climate change to further degrade fisheries resources: UBC researchers 2Great Plains river basins threatened by pumping of aquifers 2Great Plains river basins threatened by pumping of aquifers 3
(Date:12/22/2014)... DIEGO , Dec. 22, 2014 GenomeDx ... the Decipher Prostate Cancer Classifier, a genomic test for ... in node-negative, high-risk men managed by radical prostatectomy without ... radical prostatectomy is relatively uncommon, using tumor genomics to ... of metastatic disease is an important advance. The study ...
(Date:12/19/2014)... and Hershey, PA (PRWEB) December 19, 2014 ... BJCT), a leading developer and manufacturer of needle-free ... into an agreement with Immunomic Therapeutics, Inc. (“ITI”) ... needle-free injection device with its LAMP™ vaccine platform. ... option for an exclusive Worldwide license to the ...
(Date:12/19/2014)... CITY, Calif. , Dec. 19, 2014 Bina ... , USA) announced today that they have been acquired ... 1,2 is a privately held company that provides ... of next generation sequencing (NGS) data for the academic ... the Roche Sequencing Unit, and will continue to focus ...
(Date:12/19/2014)... MA (PRWEB) December 18, 2014 LayerBio ... for ophthalmology and wound care. The National Eye Institute ... awarded LayerBio a Phase I SBIR grant to develop ... Cataracts are the most common cause of vision loss ... of blindness worldwide. According to Dr. Ken Mandell, LayerBio’s ...
Breaking Biology Technology:Study Published in European Urology Shows that the Decipher Prostate Cancer Classifier is Predictive of Rapid Metastasis in High-Risk Men who have had Prostate Surgery 2Study Published in European Urology Shows that the Decipher Prostate Cancer Classifier is Predictive of Rapid Metastasis in High-Risk Men who have had Prostate Surgery 3Bioject and Immunomic Therapeutics Enter into an Agreement for License of Needle-Free Technology for LAMP-vax Vaccines 2Bioject and Immunomic Therapeutics Enter into an Agreement for License of Needle-Free Technology for LAMP-vax Vaccines 3Bina Technologies is acquired by Roche. 2Bina Technologies is acquired by Roche. 3LayerBio Awarded NIH Grant to Develop a Drug Delivery Device for Cataract Surgery 2
... 30 /PRNewswire-FirstCall/ - ICBS Limited,(PINKSHEETS: ICBM), today announced ... Bacteria Bank Ltd., is a Bio medical ... for use in medical research, located,in Montreal Canada. ... a world,renowned bacteriologist. Dr. Karl Weiss is ...
... 30 CryoCor, Inc. (Nasdaq:,CRYO), a medical device ... today that Edward F. Brennan, President and Chief,Executive ... are,scheduled to present at the CIBC World Markets ... Tuesday, November 6, 2007 at 3:40 p.m. ET ...
... ST. LOUIS, Oct. 30 Sigma, a division ... provide researchers,additional Cell Biology solutions through the new ... http://www.sigma.com/ionchannelsolutions ). In addition to the most,comprehensive product ... provide a,wealth of scientific information to assist in ...
Cached Biology Technology:ICBS acquires 30% interest in Bacteria Bank Ltd. 2CryoCor to Present at CIBC World Markets 18th Annual Healthcare Conference 2Sigma Launches The New Ion Channel Solutions Brochure and Web Site 2
...
BD Primaria 35 mm Cell Culture Dish with Easy-Grip design, surface-modified polystyrene for enhanced cell culture. (20/sp, 200/ca) Packaging: 20 / sleeve, 500 / case ...
...
BD Falcon insert HTS 96 well, square A-bottom with lid. PET membrane, sterile. (5/ca) Packaging: 5 / pack, 5 / case ...
Biology Products: