Navigation Links
Encoded metallic nanowires reveal bioweapons

When dangerous infectious diseases or biological weapons are suspected, fast help is required. The first step is a reliable, sensitive, and unambiguous, yet also fast and simple, identification of the pathogen; preferably, this test should be carried out on the spot, not in a laboratory. Portable miniature biodetection systems that can detect multiple pathogens simultaneously would be ideal for this task.

American researchers from Lawrence Livermore National Laboratory led by Jeffrey Tok, in collaboration with groups at Stanford University, University of California at Davis, and Oxonica Inc (formerly Nanoplex Technologies Inc). have now developed a new basis for such a multiplex device: they are using silver and gold "striped" nanowires as supports for simultaneous immunological tests for various pathogens. Individual patterns of stripes act in the role of "barcodes". These "nanobarcoded" particles are manufactured by Oxonica Inc using template-assisted electrochemical deposition of metals within the tiny cylindrical pores of alumina membranes. When deposited gold and silver are alternated in a defined way, nanowires with different characteristic stripe patterns are produced. The pattern of optical reflections from each sequence of stripes can later be unambiguously recognized--just like a barcode.

Antibodies aimed at specific pathogens can be attached to these wires. For their test runs, Tok and his colleagues selected harmless model substances to stand in for anthrax spores, smallpox virus, and protein toxins such as ricin and botulinum toxin. If a simultaneous test for all of these is desired, the anthrax antibody would be attached to stripe pattern 1, the smallpox antibodies to stripe pattern 2, and the toxin antibodies to stripe pattern 3, for example. If the corresponding model pathogen is present in a sample, it is "recognized" and bound by its antibodies. At this point, free antibodies that have been tagged with a fluorescent dye are added to
'"/>

Source:John Wiley & Sons, Inc.


Page: 1 2

Related biology news :

1. Elusive HIV shape change revealed; Key clue to how virus infects cells
2. Timing is everything: First step in protein building revealed
3. Researchers reveal the infectious impact of salmon farms on wild salmon
4. A bacterial genome reveals new targets to combat infectious disease
5. Scientists reveal molecular secrets of the malaria parasite
6. Studies reveal methods viruses use to sidestep immune system
7. First real-time view of developing neurons reveals surprises, say Stanford researchers
8. Examination of internal wiring of yeast, worm, and fly reveals conserved circuits
9. Family trees of ancient bacteria reveal evolutionary moves
10. NYU study reveals how brains immune system fights viral encephalitis
11. Iron exporter revealed that may explain common human disorder
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Encoded metallic nanowires reveal bioweapons

(Date:8/21/2014)... smog-producing toxins in past decade, GTA still violates ... that while the Greater Toronto Area (GTA) has ... to smog, the city continues to violate the ... can cause or aggravate health problems such as ... a set of complex photochemical reactions involving volatile ...
(Date:8/21/2014)... Nxt-ID, Inc. (OTCQB: NXTD), a biometric authentication ... today that its shares of common stock and the ... its proposed underwritten public offering of common stock and ... Capital Market, subject to closing of its proposed underwritten ... will trade under the symbol "NXTD" and "NXTDW," respectively. ...
(Date:8/21/2014)... but they are the ultimate source of all organic ... dependent on algae, too, to suck up climate-warming carbon ... bottom of the ocean. Now, by using a combination ... showing that viruses infecting those algae are driving the ... else stays essentially the same, and this has important ...
Breaking Biology News(10 mins):Despite a significant reduction in smog-producing toxins, the Greater Toronto Area still violates Canada's standards for ozone air pollution 2Nxt-ID Approved for NASDAQ Capital Market Listing 2Nxt-ID Approved for NASDAQ Capital Market Listing 3Viruses take down massive algal blooms, with big implications for climate 2
... JISC Collections has purchased the archive content of ... protocols. With immediate effect the SpringerProtocols archive content ... of charge to UK Higher and Further Education ... than 31,000 protocols, most of which come from ...
... , May 2, 2013 CDX Diagnostics, Inc ... ), filed a patent infringement action against Histologics, LLC, ... Pathology, LLP d/b/a Avero Diagnostics (collectively, "Defendants") in the ... New York . According to court ...
... New discoveries of the way plants transport important substances ... pests, increase salt and drought tolerance, control water loss ... the supply of food and energy for our rapidly ... 12 leading plant biologists from around the world whose ...
Cached Biology News:JISC Collections purchases SpringerProtocols 2Shared Medical Resources, LLC files suit against Histologics, LLC, Women's Health Laboratories and Avero Diagnostics for Willful Patent Infringement 2New plant protein discoveries could ease global food and fuel demands 2New plant protein discoveries could ease global food and fuel demands 3New plant protein discoveries could ease global food and fuel demands 4
(Date:8/21/2014)... August 21, 2014 Ontotext S4 ... by Ontotext . Now the same enterprise ... of structured and unstructured data is available to start-ups ... of enterprise technology. Organizations that do not have resources ... management can use S4 since there is no need ...
(Date:8/21/2014)... (PRWEB) August 21, 2014 ... has been recognized as one of the nation’s ... 5000 magazine for the 2nd consecutive year. Inc. ... 33rd annual Inc. 500|5000, an exclusive ranking of ... the most comprehensive look at the most important ...
(Date:8/20/2014)... , Aug. 20, 2014 Clintrax ... services located in Raleigh, NC ... Evans as Vice President of Administration. ... will oversee all corporate processes, including their alignment ... Clintrax Global, Brad worked as an HR executive, ...
(Date:8/20/2014)... history lessons often have it that American Indians largely ... chicken pox, influenza and tuberculosis brought to the New ... vary, about 20 million people lived in the Americas ... them were killed by European diseases., But new research ... University and Johannes Krause of the University of Tubingen ...
Breaking Biology Technology:Ontotext Releases Text Mining & Semantic Technology Running in the Cloud – Welcome to “S4? 2Ontotext Releases Text Mining & Semantic Technology Running in the Cloud – Welcome to “S4? 3Ontotext Releases Text Mining & Semantic Technology Running in the Cloud – Welcome to “S4? 4SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 2SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 3Clintrax Global, Inc. Announces Addition to Executive Team 2Unusual discovery leads to fascinating tuberculosis theory 2Unusual discovery leads to fascinating tuberculosis theory 3
... , , EMERYVILLE, Calif. , Feb. ... announced that it has appointed Ted W. Love , M.D., ... Michael Kauffman , M.D., Ph.D., who has served as Interim ... Chief Medical Officer reporting to Dr. Love.   , In his ...
... , , , , ... Cellectricon AB today,announced that it has resumed its litigation against ... in the United States,District Court for the Northern District ... patents issued or licensed to Cellectricon for,microfluidic technology used ...
... ... Discussion on Boston Biotech Trends and Developments, , ... Boston, MA (PRWEB) January 30, 2010 -- Caturano and Company will host ... Biotech 2010 and Beyond , on Wednesday, February 3, 2010 at their office in Charlestown, ...
Cached Biology Technology:Onyx Pharmaceuticals Appoints Ted W. Love, M.D., as Head of Research & Development 2Onyx Pharmaceuticals Appoints Ted W. Love, M.D., as Head of Research & Development 3Onyx Pharmaceuticals Appoints Ted W. Love, M.D., as Head of Research & Development 4Onyx Pharmaceuticals Appoints Ted W. Love, M.D., as Head of Research & Development 5Cellectricon Files Patent Infringement Suit Against Fluxion Biosciences 2Caturano and Company to Host Boston Biotech Event, "BIBA Biotech 2010 and Beyond" 2
... convenient, and efficient native protein concentration following ... spin column to make handling easy. The ... which were electro-eluted in their native condition. ... high binding capacity fo all pH values. ...
... Disposable. Virgin, optically clear polystyrene ... and alphanumeric coordinates for cell counting. ... number is a new product number, ... number. If showing no availability yet, ...
... The Corning CellBIND surface is produced by ... more hydrophilic surface giving more consistent, even ... CellBIND enhances cell attachment and growth uunder ... medium. • CellBIND may provide a more ...
... system, 100-240 V, uses xMAP technology for ... proteins and peptides in one microplate well. ... to 100 color-coded bead sets, each of ... reactant (enzyme substrates, receptors, antigens, or antibodies) ...
Biology Products: