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Embryo tests give parents the choice

MORE than 40 per cent of fertility clinics in the US are allowing couples to choose the sex of their child, a survey conducted by the Genetics and Public Policy Center (GPPC) in Washington DC suggests. The testing method, called preimplantation genetic diagnosis (PGD), was originally designed to test for severe or deadly diseases such as Tay-Sachs. It is typically performed by removing a cell from a three-day-old embryo, which is then screened for a range of chromosomal abnormalities or specific gene mutations. Seemingly healthy embryos are implanted in the womb; others are discarded or frozen. The survey, which covered 186 out of 415 fertility clinics in the US, found that around two-thirds of PGD procedures were performed to identify embryos at risk of birth defects or being miscarried.

However, the survey also revealed that applications of PGD have broadened to include choosing the baby's sex, as well as screening for diseases that may not strike until late in life, if at all. Non-medical sex selection accounted for 9 per cent of PGD tests conducted in the US in 2005, while 28 per cent of the clinics surveyed are now offering PGD to detect a propensity for adult-onset diseases such as Alzheimer's, Huntington's, hereditary breast cancer, and many other cancers.

PGD was originally intended to overcome infertility and to ensure that all children are born with achance of a full and flourishing life, says Eric Cohen, head of the bioethics programme at the Ethics and Public Policy Center in Washington DC. "PGD clinics are performing sex selection just to satisfy parental preferences, and embryo screening is being used for late-onset diseases that have nothing to do with childhood sickness," Cohen claims. He sees these as troubling trends.

The changes are taking place because there is little consensus on which tests are appropriate for PGD, and no federal or professional oversight of the clinics, according to Susannah Baruch, who led the GPPCstudy
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Source:New Scientist


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