Navigation Links
Electric jolt triggers release of biomolecules, nanoparticles

Johns Hopkins researchers have devised a way to use a brief burst of electricity to release biomolecules and nanoparticles from a tiny gold launch pad. The technique could someday be used to dispense small amounts of medicine on command from a chip implanted in the body. The method also may be useful in chemical reactions that require the controlled release of extremely small quantities of a material.

The technique was described Sept. 10 in a presentation by Peter C. Searson, a Johns Hopkins professor of materials science and engineering, during the 232nd national meeting of the American Chemical Society in San Francisco. "You can think of the useful biomolecule or nanoparticle as a balloon tethered to a surface," he said. "We use an electrical pulse to cut the tether, and it floats away."

This method could be used to control the release of drug molecules; nanoparticles; biopolymers such as peptides, proteins and DNA; and protein assemblies such as viruses, said Searson, who also is director of the Institute for NanoBioTechnology at Johns Hopkins.

"The technique is relatively simple, but nothing like this has been done before," he said. "Scientists have known that molecules could be removed from a surface in this way, but it's never been considered useful. They've been more interested in preventing this from happening."

Yet Searson and Johns Hopkins biomedical engineering graduate students Prashant Mali and Nirveek Bhattacharjee concluded that this controlled release of molecules might have important applications in the growing field of nanobiotechnology.

For their experiments, the researchers used gold electrodes, each as thin as a single strand of human hair, fabricated through the same photolithography techniques used to make computer chips. "We used a gold electrode because gold is a good conductor of electricity," said Mali, "and because it's an inert metal, it wouldn't get involved in any of the chemical reactions
'"/>

Source:Johns Hopkins University


Page: 1 2

Related biology news :

1. Researchers Discover That Microbes Can Produce Miniature Electrical Wires
2. What can change in the brain? Electrical synapses, research shows
3. Electric fish in Africa could be example of evolution in action
4. Scientists ID molecular switch in liver that triggers harmful effects of saturated and trans fats
5. Source of molecular triggers in cutaneous T cell lymphoma identified
6. A whole lot of shaking goin on triggers early hatching in red-eyed tree frogs
7. Nicotine triggers the same brain reward circuitry as opiates
8. Sudden change in social status triggers genetic response in male fish, study finds
9. Researchers now able to look deep into heart to view triggers of a hearts beat
10. Drug triggers bodys mechanism to reverse aging effect on memory process
11. Chemical switch triggers critical cell activities
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Electric jolt triggers release biomolecules nanoparticles

(Date:7/9/2014)... They are amongst the most numerous inhabitants of the ... . Not visible to the naked eye, when they ... sized patches, they are even visible on satellite images. ... responsible for approximately half of the global photosynthesis output," ... University Jena (Germany). In the process the greenhouse gas ...
(Date:7/9/2014)... they are used in the right ways. ... Hospital and coauthors analyzed six use cases with ... decompensation (when a patient,s condition worsens); adverse events; ... organ systems. They suspect that cost-savings benefits will ... all six scenarios will be significant. The authors ...
(Date:7/8/2014)... found the first two specimens of the prickly plant in ... the 14-inch-tall plant was identified wrongly as one species, then ... long search turned up a "pathetic, wilted" third specimen ... spiny plant as a new, possibly endangered species and named ... in Valentine, Texas, population 134 in 2010. , Most new ...
Breaking Biology News(10 mins):Short circuit in the food web 2The impact of big data on health care: Health Affairs' July issue 2New plant species from the heart of Texas 2New plant species from the heart of Texas 3New plant species from the heart of Texas 4New plant species from the heart of Texas 5
... recently developed a mathematical model of the rate ... Researchers believe this new model improves upon existing ... natural subsurface environments, the typical bacteria hangouts. This ... of important bacterial traits. , The swapping of ...
... catching an infectious disease, according to new research by ... spread far and wide. , Professor Lidia Morawska, director ... said the study dispelled the myth that viruses emitted ... , Professor Morawska and a team of ...
... with chronic herpes virus infections can better resist the ... one kind of food poisoning, researchers report in this ... Medicine in St. Louis attributed the surprising finding to ... presence of a latent herpes virus infection. In latent ...
Cached Biology News:Researchers develop way to calculate speed of bacterial sex 2Spreading viruses as we breathe 2Herpes infection may be symbiotic, help beat back some bacteria 2Herpes infection may be symbiotic, help beat back some bacteria 3Herpes infection may be symbiotic, help beat back some bacteria 4
(Date:1/15/2014)... , Jan. 15, 2014  Bill Jacobs Automotive, a group ... is teaming up with the Heartland Blood Center and offering ... drive. The drive takes place Saturday, Jan. 18 at the ... 2 p.m. (Photo: http://photos.prnewswire.com/prnh/20140115/MN46637 )  ...
(Date:1/15/2014)... (PRWEB) January 15, 2014 Look inside ... hard-working items for the lab, from fluid handling to ... (GIS)—ready to ship when you order. , Preferred ... Pumps , from the L/S® model for precise flow ...
(Date:1/15/2014)... Jan. 15, 2014 ­ RedBrick Health , a ... technology, today announces that EmblemHealth , the ... company, is now providing the RedBrick Compass health assessment, ... to all of its members. EmblemHealth is among the ...
(Date:1/15/2014)... TX (PRWEB) January 15, 2014 More ... disease, and about 1 in 3 seniors will die ... source ). These jaw-dropping figures have shocked many Americans ... and, hopefully, help prevent these tragic age-related cognitive disorders. ...
Breaking Biology Technology:Join the Bill Jacobs Auto blood drive and receive a free oil change 2Cole-Parmer Begins 2014 with the Release of Preferred Solutions 2EmblemHealth Selects RedBrick Health to Power its Next-Generation Health Engagement and Behavior Change System 2EmblemHealth Selects RedBrick Health to Power its Next-Generation Health Engagement and Behavior Change System 3Biohack Pure Offers 5 Tips for Increasing Memory in 2014 2
... this year, the ongoing saga of the consolidating pharmaceutical industry ... news over the last two weeks, were talking about the ... take over French-German pharmaceutical giant Aventis . , ... If it happens, the combined company would create the worlds ...
... -- Pulling an all-nighter has never been so profitable ... School students who won a venture capital (VC) ... all MBA students, secured the win from a panel ... , ,The new competition, called Venture Capital Spring Training, ...
... , a maker of molecular diagnostic products, recently announced ... provides clinical trial laboratories with access to a broad ... gene. , ,The panel is a pharmacogenetic testing solution ... custom assay panels. The panel is being used to ...
Cached Biology Technology:The Industry Impact of Two Big Pharmas Mating 2The Industry Impact of Two Big Pharmas Mating 3The Industry Impact of Two Big Pharmas Mating 4The Industry Impact of Two Big Pharmas Mating 5The Industry Impact of Two Big Pharmas Mating 6The Industry Impact of Two Big Pharmas Mating 7VC Contest Winners Learn from Experience 2Third Wave Releases Gene Test 2
... Escherichia coli RY 13 5'G AATTC3' 3'CTTAA G5' ... min or ethanol precipitation. Storage Conditions: 10mM Tris-HCl ... 0.15% Triton X-100, 0.01% BSA, 50% glycerol. Shipping ... -20C. Unit Definition: One unit is defined as ...
... LabWorks Software provides a comprehensive experiment based ... drop down menus yet sophisticated and powerful ... dozens of CCD cameras for easy image ... , Automated Digital Video Playback ...
... Heavy duty stainless-steel shaker flask clips, purpose-designed ... speeds. All clips are equipped with ... 1L.) also include a bottom retainer spring, ... scratching of expensive glassware. Clips include ...
... mix (Thermoprime Plus DNA Polymerase with a ... times higher fidelity than standard Taq DNA ... DNA polymerase, Amplifies DNA templates >20kb, Concentration: ... PCR for cloning and mutagenesis We are ...
Biology Products: