Navigation Links
Einstein's tea leaves inspire new blood separation technique

Scientists at Monash University in Australia have developed a process for rapidly and efficiently separating blood plasma at the microscopic level without any moving parts, potentially allowing doctors to do blood tests without sending samples to a laboratory. The new method uses the same principle that causes tea leaves to accumulate at the center of the bottom in a stirred teacup, a phenomenon first explained by Einstein in the 1920s.

The research was done by Drs. Dian R. Arifin, Leslie Y. Yeo and James R. Friend, of Monash University's Micro/Nanophysics Research Laboratory in the Department of Mechanical Engineering. The researchers' findings are published in the current issue of the new open-access journal Biomicrofluidics (http://bmf.aip.org).

Separating blood plasma from red blood cells, proteins and other microscopic particles is an essential step in many common medical tests, including those for cholesterol levels, drugs in athletes, blood types in donors and glucose levels in diabetics. Current testing requires samples to be taken in a doctor's office and sent off to a laboratory and analyzed with a large centrifuge, a process that can take several days.

In the new method, a tiny amount of blood enters a fluid chamber, and a needle tip is placed close to the surface of the blood at an angle. A voltage is applied to the needle, generating ions around its tip that repel the oppositely charged ions close to it. This creates an airflow known as "ionic wind" that sweeps across the surface of the blood, causing it to circulate. The microscopic particles in the blood travel in a downward spiral because of the needle's angle relative to the surface.

When the fluid begins to circulate, one might intuitively expect the microscopic particles such as red blood cells would be pulled to the outside wall of the chamber owing to centrifugal force. But because of a phenomenon called the "tea leaf paradox," the particles are instead pulled i nward near the bottom of the chamber. Einstein proposed an explanation to this phenomenon in 1926 when he noticed that tea leaves collected at the center of the bottom of a stirred teacup instead of being expelled outward.

The tiny chamber of blood, like the teacup, is a cylinder of liquid that is rotated at the top while the base remains stationary. To satisfy a zero-velocity condition at the base, an inward force near the bottom of the liquid is generated, suppressing the centrifugal force there. Thus the microscopic particles spiral inward toward the bottom of the chamber like a miniature tornado, leaving a clear layer of plasma above.

Yeo anticipates the technology could be incorporated into a chip roughly the size of a credit card. He said the devices could be produced cheaply with current manufacturing techniques -- about 50 cents per chip -- but could still be five to 10 years away from mass production.


'"/>

Source:American Institute of Physics


Related biology news :

1. Depression model leaves mice with molecular scar
2. Researchers discover way to transport environmental arsenic to plant leaves in new clean-up strategy
3. Researchers offer clues to how leaves patterns are formed
4. Ghost protein leaves fresh tracks in the cell
5. Beetle-inspired switch uses water for bonding
6. Nanotubes inspire new technique for healing broken bones
7. UC Berkeley researchers create a biologically-inspired artificial compound eye
8. Methane-belching bugs inspire a new theory of the origin of life on Earth
9. Squid-inspired design could mean better handling of underwater vehicles
10. Biologically inspired sensors can augment sonar, vision system in submarines
11. White blood cell waste disposal system plays critical regulatory role
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/20/2016)... 20, 2016  Synaptics Incorporated (NASDAQ: SYNA ... today announced sampling of S1423, its newest ClearPad ... small screen applications including smartwatches, fitness trackers, and ... and rectangular shapes, as well as thick and ... moisture on screen, while wearing gloves, and supports ...
(Date:1/15/2016)... , Jan. 15, 2016 Recent publicized ... small to find new ways to ensure data security ... iOS and Android that ties ... biometrics, transforming it into a hardware authorization token. Customer ... swipe their fingerprint on their KodeKey enabled device to ...
(Date:1/13/2016)... , January 13, 2016 /PRNewswire/ ... announced the addition of the  "India ... Estimation & Forecast (2015-2020)"  report ... http://www.researchandmarkets.com/research/7h6hnn/india_biometrics ) has announced the addition ... Identification Market - Estimation & Forecast ...
Breaking Biology News(10 mins):
(Date:2/8/2016)... (PRWEB) , ... February 08, 2016 , ... Information Management ... Web product. The upgrade represents a completely new technical foundation and is so ... offer a responsive design interface, significantly increased speed for search results, a streamlined layout ...
(Date:2/8/2016)... Feb. 8, 2016  Diplomat Pharmacy, Inc. (NYSE: DPLO) announced today that its new website has ... resource–user-centric, story-driven, knowledge-based and mobile-friendly. Visit the new ... ... ... "The goal was to reimagine ...
(Date:2/5/2016)... , Feb. 5, 2016  In the pharmaceutical ... for a host of launch activities including the identification ... this launch activity is especially high in the oncology ... Best Practices and the Role of Medical Affairs ... companies focused on oncology therapies find better ways to ...
(Date:2/4/2016)... - New FDA action date of July 22, ... July 22, 2016   --> - ...   - Lifitegrast has the potential to be the ... signs and symptoms of dry eye disease in adults ... product approved in the U.S. in the past decade indicated for the treatment of ...
Breaking Biology Technology: