Navigation Links
Edible bivalves as a source of human pathogens: signals between vibrios and the bivalve host.

Clams, mussels and oysters are important vehicles for the transmission of enteric diseases when consumed raw or undercooked. Vibrio species, including human pathogens, are particularly abundant in bivalve tissues, where they can persist even after cleaning procedures, thus representing a potential risk for human health. Although different environmental factors are well known to affect the persistence of vibrios in these organisms, the key role of the interactions between vibrios and the immune system of bivalves has been recently highlighted by scientists from the Universities of Genova and Urbino (Italy) in Environmental Microbiology.

Carla Pruzzo, from the University of Genova explains: "In bivalves, immunity is carried out by circulating haemocytes and soluble haemolymph factors that act in a co-ordinate way to kill microorganisms. Our research examines available data on Vibrio interactions with both cellular and soluble components of the bivalve immune system in the light of the capacity of bacteria to evade the hemolymph bactericidal activity and to develop pathogenic effects in the bivalve host."

The authors describe their data obtained with an in vitro model of Vibrio cholerae challenged against the immune system of Mytilus galloprovincialis, chosen as representative of important and appreciated seafood in the Mediterranean area. The results obtained allowed the identification of factors that are important in determining the fate of vibrios within the bivalve host, such as bacterial surface ligands, soluble hemolymph components and the ability of bacteria to affect distinct signaling pathways responsible for the hemocyte immune response.

Laura Canesi, from the University of Urbino adds "In bivalve hemocytes, different Vibrio species and strains seem to adopt a common strategy utilized by pathogenic bacteria in mammalian cells: to undermine host cell functions through disregulation of its signaling pathways".

This research gives an insight into the complexity of signals that pass between vibrios and bivalve host cells and helps to explain how these processes develop in natural conditions and determine the fate of vibrios in the bivalve host.


'"/>

Source:Blackwell Publishing Ltd.


Related biology news :

1. Edible coatings will be the packaging of the future
2. Spleen may be source of versatile stem cells
3. Poplar trees redirect resources in response to simulated attack
4. The BIOS Initiative - open source biotechnology is born
5. Microbial fuel cell: High yield hydrogen source and wastewater cleaner
6. Birds brains reveal source of songs
7. Fats fate depends on its source
8. Amazon source of 5-year-old river breath
9. Hybrid grass may prove to be valuable fuel source
10. Seal rookeries could provide a reliable food source for endangered California condors, study finds
11. Microbiology text tells stories, offers online resources
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/15/2016)... 15, 2016 Research and ... Biometrics Market 2016-2020,"  report to their offering.  , ... , ,The global gait biometrics market is expected ... the period 2016-2020. Gait analysis generates ... be used to compute factors that are not ...
(Date:4/13/2016)... 13, 2016  IMPOWER physicians supporting Medicaid patients in ... new clinical standard in telehealth thanks to a new ... higi platform, IMPOWER patients can routinely track key health ... mass index, and, when they opt in, share them ... to a local retail location at no cost. By ...
(Date:3/31/2016)... , March 31, 2016  Genomics firm Nabsys ... founding CEO, Barrett Bready , M.D., who returned ... of the original technical leadership team, including Chief Technology ... of Product Development, Steve Nurnberg and Vice President of ... to the company. Dr. Bready served as ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... 27, 2016   Ginkgo Bioworks , a leading ... was today awarded as one of the World ... world,s most innovative companies. Ginkgo Bioworks is engineering ... real world in the nutrition, health and consumer ... with customers including Fortune 500 companies to design ...
(Date:6/24/2016)... ... ... Researchers at the Universita Politecnica delle Marche in Ancona combed medical journal ... Their findings are the subject of a new article on the Surviving Mesothelioma website. ... the blood, lung fluid or tissue of mesothelioma patients that can help point doctors ...
(Date:6/23/2016)... 23, 2016 /PRNewswire/ - FACIT has announced the ... biotechnology company, Propellon Therapeutics Inc. ("Propellon" or ... of a portfolio of first-in-class WDR5 inhibitors for ... as WDR5 represent an exciting class of therapies, ... medicine for cancer patients. Substantial advances have been ...
(Date:6/23/2016)... SANTA MONICA, Calif. , June 23, 2016  The Prostate Cancer ... to pioneer increasingly precise treatments and faster cures for prostate cancer. Members of ... 77 institutions across 15 countries. Read More About the ... ... ...
Breaking Biology Technology: