Navigation Links
Eating protein boosts hormone that staves off hunger

The amount of a hunger-fighting hormone can be increased by eating a higher protein diet, researchers report in the September issue of the journal Cell Metabolism, published by Cell Press. The hormone, known as peptide YY (PYY), was earlier found by the researchers to reduce food intake by a third in both normal-weight and obese people when given by injection.

"We've now found that increasing the protein content of the diet augments the body's own PYY, helping to reduce hunger and aid weight loss," said Medical Research Council clinician scientist Rachel Batterham of University College London, who led the new study.

Scientists have known that high-protein content meals make people feel more full and reduce food intake, resulting in improvements in weight loss and weight loss maintenance. However, the mechanism responsible remained elusive.

In a study in normal-weight and obese people, the researchers now show that enhanced-protein meals stimulate greater release of PYY than either high-fat or high-carbohydrate meals and result in a greater reduction of hunger.

Further investigation in mice supported the human study results. High-protein diets reduced the number of calories animals consumed and increased their PYY levels. Mice fed a high-protein diet also gained less weight and produced more PYY than animals that ate the usual amount of protein, they found.

In addition, the researchers found that genetically modified mice unable to produce PYY ate more and became markedly obese. The genetically modified mice were also resistant to the beneficial effects of a high-protein diet, the researchers reported, demonstrating a direct connection between protein and PYY.

When the researchers treated those hormone-deficient mice with PYY, the animals lost weight.

"The findings show that PYY deficiency can cause obesity and that PYY appears to mediate the beneficial effects of increased-protein content diets," Batterha m said. "One potential weight loss strategy is therefore to increase the satiating power of the diet and promote weight loss through the addition of dietary protein--harnessing our own satiety system.

"Such a diet is perhaps more typical to that of our hunter-gatherer ancestors," she added.

The average Western diet derives 49% of energy intake from carbohydrate, 35% from fat, and 16% from protein, Batterham said. That differs considerably from the diet of hunter-gatherers, who ate as much as twice the amount of protein.

Batterham cautioned, however, that large, long-term clinical trials are required before any particular diet could be recommended. She also noted that such a diet would not resemble the popular Atkins diet, which is typically high in both saturated fat and protein.


'"/>

Source:Cell Press


Related biology news :

1. Eating, body weight regulated by specific neurons
2. Eating less salt could prevent cardiovascular disease
3. Eating with our eyes: Why people eat less at unbused tables
4. New, automated tool successfully classifies and relates proteins in unprecedented way
5. New binding target for oncogenic viral protein
6. Controversial drug shown to act on brain protein to cut alcohol use
7. Timing is everything: First step in protein building revealed
8. UWs Rosetta software to unlock secrets of many human proteins
9. Researchers find how protein allows insects to detect and respond to pheromones
10. Signaling protein builds bigger, better bones in mice
11. Ancient olfaction protein is shared by many bugs, offering new pest control target
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/9/2016)... , June 9, 2016 ... deploy Teleste,s video security solution to ensure the safety of ... during the major tournament Teleste, an ... systems and services, announced today that its video security solution ... to back up public safety across the country. The ...
(Date:6/2/2016)... June 2, 2016 Perimeter Surveillance ... Unmanned Systems, Physical Infrastructure, Support & Other Service  ... visiongain offers comprehensive analysis of the global ... will generate revenues of $17.98 billion in 2016. ... Inc, a leader in software and hardware technologies for ...
(Date:5/12/2016)... , May 12, 2016 WearablesResearch.com , ... published the overview results from the Q1 wave of ... recent wave was consumers, receptivity to a program where ... with a health insurance company. "We were ... share," says Michael LaColla , CEO of Troubadour ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... , ... June 24, 2016 , ... Researchers at the ... commonly-identified miRNAs in people with peritoneal or pleural mesothelioma. Their findings are the subject ... it now. , Diagnostic biomarkers are signposts in the blood, lung fluid or ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... to announce the launch of their brand, UP4™ Probiotics, into Target stores nationwide. ... years, is proud to add Target to its list of well-respected retailers. This ...
(Date:6/23/2016)... 23, 2016 /PRNewswire/ - FACIT has announced the ... biotechnology company, Propellon Therapeutics Inc. ("Propellon" or ... of a portfolio of first-in-class WDR5 inhibitors for ... as WDR5 represent an exciting class of therapies, ... medicine for cancer patients. Substantial advances have been ...
(Date:6/23/2016)... HOUSTON , June 23, 2016 ... agreement with the Cy-Fair Sports Association to serve ... of the agreement, Houston Methodist Willowbrook will provide ... education and connectivity with association coaches, volunteers, athletes ... partner with the Cy-Fair Sports Association and to ...
Breaking Biology Technology: