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Eat less, weigh more? Enzyme makes lean mice 'susceptible' to dietary fat

o use more energy. Therefore, identifying molecules that interact with malonyl-CoA will help scientists understand how energy balance and body weight is controlled.

"We are beginning to understand what the hypothalamus inputs are, but unlike the liver, where nearly the whole organ is involved in the same thing, the brain is very specialized and only a few neurons do very specific things," says Lane. The researchers hope to further understand how malonyl-CoA and CPT1c function to control body weight and appetite.
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Source:Johns Hopkins Medical Institutions


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