Navigation Links
Dual-imaging technique useful before -- and during -- brain surgery

Brain specialists associated with the Neuroscience Institute at the University of Cincinnati (UC) and University Hospital say the ability to incorporate—in real time—two high-tech imaging tools into the operating room can improve the functional abilities of patients who undergo brain surgery.

Neuroradiologist James Leach, MD, and his UC colleagues are among the first in the United States to combine functional magnetic resonance imaging (MRI) and “diffusion tensor tractography” data to outline important areas of brain function and their connections prior to surgery—and then transfer that data to the operating room to track those areas during actual surgery.

This approach, Leach says, has already been used in 20 cases at Cincinnati’s University Hospital.

“Combining tractography and functional MRI intraoperatively has been in use clinically for only a few years,” says Leach, associate professor of radiology at UC and a neuroradiologist with University Hospital, “but our preliminary data is very promising because it allows us to optimize surgical approaches to treating brain tumors to ultimately improve patient outcomes.”

He says that combining standard visual, sound, and voice-based tests, whose results are measured by MRI, performed on a high-field-strength (3 Tesla) scanner, with a precise intraoperative guidance system will improve patients’ post-operative speech, movement and memory, and also optimize quality of life for those with brain tumors and other neurological conditions.

Leach will present this preliminary research in a special scientific exhibit at the American Society of Neuroradiology’s annual meeting, June 9–13 in Chicago.

To combine both functional MRI and diffusion tensor tractography images in the operating room, Leach and his colleagues use a high-tech surgical navigation system known as BrainLAB. The BrainLAB technology incorporates functional MRI data to identify brain areas linked t o speech, movement and vision, and diffusion tensor imaging data to map critical “white-matter tracts”—the electrical connections between different parts of the brain that should be avoided during surgery.

Leach says the detailed, easy-to-understand images produced from functional MRI data also help patients understand what is happening in their head and how the surgery will be conducted.

“We can essentially show patients a color-coded picture of their brain and explain to them where their tumor is in relation to areas that control critical functions like expressive speech, movement and vision,” says Leach. “This can help alleviate the patient’s apprehension and help explain what will happen during surgery.”

Although researchers expect this dual-imaging technique to become standard practice across the United States in the next five years, there are still limitations. For example, explains Leach, patients with limited vision may not demonstrate as much activity in the brain in areas linked to vision during functional MRI testing.

“That doesn’t necessarily mean that there’s no function there—it may just be that functional MRI is not sensitive enough to detect it,” says Leach.

Source:University of Cincinnati

Related biology news :

1. New lab technique identifies high levels of pathogens in therapy pool
2. Brain-mapping technique aids understanding of sleep, wakefulness
3. Study reveals new technique for fingerprinting environmental samples
4. Researchers pioneer new gene therapy technique using natural repair process
5. Newer imaging techniques may lead to over-treatment
6. Gene silencing technique offers new strategy for treating, curing disease
7. Mosaic mouse technique offers a powerful new tool to study diseases and genetics
8. Researchers devise new technique for creating human stem cells
9. New technique rapidly detects illness-causing bacteria
10. New bioinformatics technique for systematically analyzing key regions in DNA that help control gene activity
11. New technique may speed DNA analysis

Post Your Comments:

(Date:11/26/2015)... DUBLIN , Nov. 26, 2015 Research ... of the "Capacitive Fingerprint Sensors - Technology and ... --> --> ... market, especially in smartphones. The fingerprint sensor vendor Idex ... fingerprint sensor units in mobile devices and of the ...
(Date:11/20/2015)... , November 20, 2015 ... company focused on the growing mobile commerce market and ... Gino Pereira , was recently interviewed on ... will air on this weekend on Bloomberg Europe ... America . --> NXTD ) ("NXT-ID" or ...
(Date:11/19/2015)... , Nov. 19, 2015  Based on its ... & Sullivan recognizes BIO-key with the 2015 Global Frost ... year, Frost & Sullivan presents this award to the ... catering to the needs of the market it serves. ... line meets and expands on customer base demands, the ...
Breaking Biology News(10 mins):
(Date:11/30/2015)... ... November 30, 2015 , ... ... tighter software integration with MarkLogic, the Enterprise NoSQL database platform provider, creating ... drive change. , Smartlogic’s Content Intelligence capabilities provide a robust set of ...
(Date:11/30/2015)... and PETACH TIKVAH, Israel , Nov. 30, ... BCLI ), a leading developer of adult stem cell technologies ... Cell Therapeutics Ltd., has been awarded an additional grant of ... the Chief Scientist (OCS). This grant, the second this year, ... activities to approximately $1.8 million (approximately NIS7 million).  ...
(Date:11/28/2015)... Seoul, South Korea (PRWEB) , ... November 28, 2015 , ... ... new class of eco-friendly avian, porcine and rodent control solutions , ... such as peppermint and cinnamon oil, works across all sensory modalities including visual, smell, ...
(Date:11/27/2015)... /PRNewswire/--  Mallinckrodt plc (NYSE: MNK ), a ... closed the sale of its global contrast media and ... in a transaction valued at approximately $270 million. The ... total of approximately 1,000 employees spread across the globe, ... area. This entire workforce and the manufacturing ...
Breaking Biology Technology: