Navigation Links
Dual-imaging technique useful before -- and during -- brain surgery

Brain specialists associated with the Neuroscience Institute at the University of Cincinnati (UC) and University Hospital say the ability to incorporate—in real time—two high-tech imaging tools into the operating room can improve the functional abilities of patients who undergo brain surgery.

Neuroradiologist James Leach, MD, and his UC colleagues are among the first in the United States to combine functional magnetic resonance imaging (MRI) and “diffusion tensor tractography” data to outline important areas of brain function and their connections prior to surgery—and then transfer that data to the operating room to track those areas during actual surgery.

This approach, Leach says, has already been used in 20 cases at Cincinnati’s University Hospital.

“Combining tractography and functional MRI intraoperatively has been in use clinically for only a few years,” says Leach, associate professor of radiology at UC and a neuroradiologist with University Hospital, “but our preliminary data is very promising because it allows us to optimize surgical approaches to treating brain tumors to ultimately improve patient outcomes.”

He says that combining standard visual, sound, and voice-based tests, whose results are measured by MRI, performed on a high-field-strength (3 Tesla) scanner, with a precise intraoperative guidance system will improve patients’ post-operative speech, movement and memory, and also optimize quality of life for those with brain tumors and other neurological conditions.

Leach will present this preliminary research in a special scientific exhibit at the American Society of Neuroradiology’s annual meeting, June 9–13 in Chicago.

To combine both functional MRI and diffusion tensor tractography images in the operating room, Leach and his colleagues use a high-tech surgical navigation system known as BrainLAB. The BrainLAB technology incorporates functional MRI data to identify brain areas linked t o speech, movement and vision, and diffusion tensor imaging data to map critical “white-matter tracts”—the electrical connections between different parts of the brain that should be avoided during surgery.

Leach says the detailed, easy-to-understand images produced from functional MRI data also help patients understand what is happening in their head and how the surgery will be conducted.

“We can essentially show patients a color-coded picture of their brain and explain to them where their tumor is in relation to areas that control critical functions like expressive speech, movement and vision,” says Leach. “This can help alleviate the patient’s apprehension and help explain what will happen during surgery.”

Although researchers expect this dual-imaging technique to become standard practice across the United States in the next five years, there are still limitations. For example, explains Leach, patients with limited vision may not demonstrate as much activity in the brain in areas linked to vision during functional MRI testing.

“That doesn’t necessarily mean that there’s no function there—it may just be that functional MRI is not sensitive enough to detect it,” says Leach.
'"/>

Source:University of Cincinnati


Related biology news :

1. New lab technique identifies high levels of pathogens in therapy pool
2. Brain-mapping technique aids understanding of sleep, wakefulness
3. Study reveals new technique for fingerprinting environmental samples
4. Researchers pioneer new gene therapy technique using natural repair process
5. Newer imaging techniques may lead to over-treatment
6. Gene silencing technique offers new strategy for treating, curing disease
7. Mosaic mouse technique offers a powerful new tool to study diseases and genetics
8. Researchers devise new technique for creating human stem cells
9. New technique rapidly detects illness-causing bacteria
10. New bioinformatics technique for systematically analyzing key regions in DNA that help control gene activity
11. New technique may speed DNA analysis

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/20/2016)... -- VoiceIt is excited to announce its new marketing ... working together, VoiceIt and VoicePass will offer an ... slightly different approaches to voice biometrics, collaboration between ... Both companies ... "This marketing and technology partnership allows VoiceIt ...
(Date:4/28/2016)... BANGALORE, India , April 28, 2016 /PRNewswire/ ... product subsidiary of Infosys (NYSE: INFY ), and ... global partnership that will provide end customers with ... banking and payment services.      (Logo: http://photos.prnewswire.com/prnh/20130122/589162 ... area for financial services, but it also plays a fundamental ...
(Date:4/15/2016)...  A new partnership announced today will help ... in a fraction of the time it takes ... life insurance policies to consumers without requiring inconvenient ... Diagnostics, rapid testing (A1C, Cotinine and HIV) and ... weight, pulse, BMI, and activity data) available at ...
Breaking Biology News(10 mins):
(Date:5/23/2016)... , May 23, 2016 Oxitec CEO ... th at 10:15 a.m. ET before the United States ... genetically engineered mosquitos can play in controlling the spread of ... the Zika virus.      (Logo: http://photos.prnewswire.com/prnh/20150630/227348 ... mosquito with a self-limiting gene. Trials in Brazil ...
(Date:5/23/2016)... ... May 23, 2016 , ... RoviSys, ... services based in Aurora, Ohio, has broken ground on a new building in ... Triangle Park area, this new location solidifies a commitment to business in the ...
(Date:5/22/2016)... ... May 22, 2016 , ... Doctors in Rome say micronutrients found in ... malignant mesothelioma. Surviving Mesothelioma has just posted an article on the new research. ... Department of Clinical Sciences and Translational Medicine evaluated more than 150 studies on polyphenols ...
(Date:5/20/2016)... Minneapolis, MN (PRWEB) , ... May 20, 2016 , ... ... and consumer goods companies, today announced its official 25th anniversary of the business. “We ... we are so grateful to our customers for the privilege and honor of serving ...
Breaking Biology Technology: