Navigation Links
Diabetes research takes wing thanks to long-lived fruit fly

The creation of an extraordinarily long-lived fruit fly by genetics researchers at the University of Rochester has led scientists down an unexpected new path in the fight against diabetes. The mutant fly is serving as a portal for understanding the factors that determine how nutrition and stress set the foundation for metabolic syndrome and diabetes, why diabetes occurs more frequently as people age, and indeed why people live as long as they do.

Dirk Bohmann, Ph.D., and Henri Jasper, Ph.D., are focusing on a cell signaling system that responds to stress and works in tandem with the insulin receptor that is central to diabetes. They recently received $2.5 million from the National Institutes of Health to conduct the next phase of their studies.

Why spend such funds on a fly that lives 40 percent longer than the average fly? Because of its promise for human health. New findings on aging, diabetes, and stress converge on the fly the team created. Later this month Bohmann will discuss the fly's implications for aging and health at a symposium in Sweden sponsored by the Wenner-Gren Foundations and also at the exclusive International Workshop on the Molecular and Developmental Biology of Drosophila, sponsored by the European Molecular Biology Organization, in Crete.

Bohmann and Jasper showed in 2003 that boosting the amount of a molecular signal known as JNK in a fruit fly allows the fly to live 85 days instead of 60, by spurring the fly to defend itself more aggressively against the oxidative stress that accelerates with aging. Such stress comes from the same chemical process that makes cars rust in the Rochester winter: Free-wheeling molecules known as free radicals zing through materials and run roughshod over anything in their way, including vital proteins and DNA. It's a major reason why generally our bodies falter as we age ?we're literally dinged to death by free radicals.

While scientists knew that JNK in a fly cranks up the anti-ox
'"/>

Source:University of Rochester Medical Center


Page: 1 2 3 4

Related biology news :

1. FDA Approves New Drug to Treat Type I and Type II Diabetes
2. First North American Encapsulated Islet Transplant without Long-term Immune Suppression into a Patient with Type 1 Diabetes
3. Single-donor Islet Transplantation Procedure Shows Promise For Patients With Type 1 Diabetes
4. Precise Timing Enabled Pig-to-rat Transplants To Cure Diabetes
5. Diabetes researchers pioneer islet cell xenotransplantation in primate studies
6. Diabetes hits 275 Australians each day as pandemic spreads
7. Diabetes slows nerve recovery after heart transplant
8. Columbia research lifts major hurdle to gene therapy for cancer
9. U of M researcher examines newly emerging deadly disease
10. NYU researchers simulate molecular biological clock
11. First atlas of key brain genes could speed research on cancer, neurological diseases
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Diabetes research takes wing thanks long lived fruit fly

(Date:3/17/2015)... MINNETONKA, Minn. , March 17, 2015 /PRNewswire/ ... sciences technology company specializing in clinical study management ... will be in attendance at ARENA,s Outsourcing in ... Cary, NC.  This event provides an excellent forum ... company,s easy-to-use, flexible and affordable software-as-a-service (SaaS) eClinical ...
(Date:3/12/2015)... 12, 2015 IriTech, a leading iris based ... the Texas Instruments Design Network, announced today that the ... its IriShield USB MK2120U device during a launching event ... distribution. The iris scanner is manufactured ... in India through its Indian ...
(Date:3/11/2015)... DUBLIN , Mar. 11, 2015 Research and ... addition of the "Access Control Market by Product, ... to 2020" report to their offering. , ... is expected to reach $10.4 billion by 2020, with ... control market report covers the products types such as ...
Breaking Biology News(10 mins):Connect With MedNet Solutions At Outsourcing In Clinical Trials Southeast 2Indian States See IriTech's Scanner Bolstering Efficiency of Authentication for Aadhaar 2Indian States See IriTech's Scanner Bolstering Efficiency of Authentication for Aadhaar 3Global Access Control (Cards & Readers, Biometrics, Controllers, Management Software) Market 2015-2020 - Analysis of the $10 Billion Market 2
... are social butterflies. They constantly interact with their surroundings, taking ... themselves, among other critical tasks. This networking is driven ... cell,s outer plasma membrane. Their job is to convert mechanical ... tell the cell what to do. That is, when they ...
... Springer and Politecnico di Milano will partner to publish ... will consist of concise summaries of cutting-edge research and ... books in the series are available as eBooks on ... (POD) format. The POLIMI SpringerBriefs will cover ...
... a series of research cruises to understand the impact of ... West Europe. The 3.2 million study focuses on the ... - play in the cycling of carbon and nutrients, and ... study will be carried out on RRS Discovery, the Natural ...
Cached Biology News:Computer simulations yield clues to how cells interact with surroundings 2Computer simulations yield clues to how cells interact with surroundings 3Scientists awarded £3M to study the way Northwest European seas absorb carbon 2
(Date:3/30/2015)... PMG Research, Benchmark Research, and Miami ... of VaxCorps, a network of highly experienced, geographically ... of vaccine trials in healthy adult, elderly, and ... conducted over 500 phase I-III vaccine clinical trials, ... as well as a vast array of other ...
(Date:3/30/2015)... NEW BRUNSWICK, N.J. , March 30, 2015 /PRNewswire-USNewswire/ ... research and innovation projects in the state of ... to its next round of grant funding, announced ... existing New Jersey Health Foundation Research Grants program, an ... to $35,000 each to fund early stage research projects ...
(Date:3/30/2015)... GERMANTOWN, Md. , March 30, 2015  /PRNewswire/ ... a leader in synthetic biology, and Merck Serono, ... Germany , today announced an exclusive ... commercialize Chimeric Antigen Receptor T-cell (CAR-T) cancer therapies. ... to develop innovative therapies that modulate the immune ...
(Date:3/30/2015)... March 30, 2015  Naldemedine, an investigational peripherally ... Shionogi & Co., Ltd., met its primary and ... I) for the treatment of opioid-induced constipation (OIC) ... opioid therapy. Study results showed that naldemedine (0.2 ... the frequency of spontaneous bowel movement (SBM) compared ...
Breaking Biology Technology:PMG Research announces formation of VaxCorps with two industry-leading vaccine site networks 2New Jersey Health Foundation Announces An Additional $1 Million To Fund Innovation and Research Grants in New Jersey 2Intrexon and Merck Serono Announce Agreement for the Development and Commercialization of CAR-T Therapy 2Intrexon and Merck Serono Announce Agreement for the Development and Commercialization of CAR-T Therapy 3Intrexon and Merck Serono Announce Agreement for the Development and Commercialization of CAR-T Therapy 4Shionogi & Co., Ltd. Announces That Naldemedine Meets Primary Endpoint In A Phase 3 Study For The Treatment Of Opioid-Induced Constipation 2Shionogi & Co., Ltd. Announces That Naldemedine Meets Primary Endpoint In A Phase 3 Study For The Treatment Of Opioid-Induced Constipation 3
... YORK, Oct. 29 Reportlinker.com announces ... is available in its catalogue. , ... and Scanning SEM Electron Microscope Market ... 2015 , ...
... Calif. & HAMILTON, New Zealand, Oct. 29 ZyGEM ... DNA extraction and other life sciences applications, today announced ... Japan to distribute ZyGEM,s DNA extraction products to the ... in a series of recent major distribution agreements for ...
... , ... Access IR/PR, a San Diego-based investor and ... corporate/financial communications consultancy based in Boston, have formed a strategic alliance. ... firms, clients and provides extended access to key financial, investor and ...
Cached Biology Technology:Reportlinker Adds Worldwide Optical, Transmission TEM, and Scanning SEM Electron Microscope Market Shares, Strategies, and Forecasts, 2009 to 2015 2Reportlinker Adds Worldwide Optical, Transmission TEM, and Scanning SEM Electron Microscope Market Shares, Strategies, and Forecasts, 2009 to 2015 3Reportlinker Adds Worldwide Optical, Transmission TEM, and Scanning SEM Electron Microscope Market Shares, Strategies, and Forecasts, 2009 to 2015 4Reportlinker Adds Worldwide Optical, Transmission TEM, and Scanning SEM Electron Microscope Market Shares, Strategies, and Forecasts, 2009 to 2015 5ZyGEM Strengthens its Worldwide Presence With New Distribution Agreement for Japan 2ZyGEM Strengthens its Worldwide Presence With New Distribution Agreement for Japan 3ZyGEM Strengthens its Worldwide Presence With New Distribution Agreement for Japan 4Investor Relations Firm Access IR/PR and The Communications Strategy Group Announce Strategic Alliance 2
... Sytem is a highly advanced digital ... digital imaging and automation technology that ... analysis, archving/retrieval and colored professional reporting. ... industry's fastest scanning and detection modules ...
... with temperature probe, 100-120 and 220-240 V, supports ... and 400 W. The temperature probe is used ... degrees C during electrophoresis. Built-in infrared capability allows ... are provided. Dimensions are 27.5 x 34 x ...
... mini IEF cell is an apparatus dedicated ... polyacrylamide or agarose slab gels. The cell ... electrodes, casting tray, 5 glass plates, 50 ... 5 sample templates, and instructions. Dimensions are ...
... The Biomek FX provides ... analysis applications. With 96-, ... pipetting heads in either single ... Biomek FX offers maximum speed ...
Biology Products: