Navigation Links
Development of gene therapy

Since the late 1980s, gene therapy, more than virtually any other type of therapy, has given rise not only to high expectations of treatment success but also great concerns regarding health risks. Since the Deutsche Forschungsgemeinschaft (German Research Foundation, DFG) issued its first memorandum in 1995, this field of research has developed enormously.

Wide-ranging experiments have shown the therapeutic potential as well as the risks of gene therapy. The second memorandum, which has just been presented by the DFG Senate Commission on Genetic Research, makes it clear that gene therapy already shows signs of success in certain areas, such as severe hereditary immunodeficiency diseases, while in other areas there is still considerable need for research. Moreover, the clinical application of gene therapy requires careful risk/benefit assessment, although in this respect it does not differ substantially from other therapeutic approaches.

Gene therapy is defined as the introduction of genes into tissues or cells via gene transfer, with the purpose of deriving a therapeutic or preventative benefit from the function of these genes. Gene transfer is achieved using a vector ? a kind of vehicle that carries the gene. Somatic gene transfer only targets body cells (somatic cells). Introducing genes into the germline is illegal in Germany. The first well-documented gene therapy studies were launched in the early 1990s. By 2005 it was estimated that more than 1,100 gene therapy studies had been conducted worldwide, one-third of them in Europe, and a significant number in Germany. The DFG is currently funding a Priority Programme for research groups, some of which are international leaders in their field, that examine the entry and persistence of gene therapy vectors in target cells.

In spite of continued great difficulties with technical implementation, initial successes in somatic gene therapy are on the horizon, for example in treating adenosine deam
'"/>

Source:Deutsche Forschungsgemeinschaft


Page: 1 2

Related biology news :

1. Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease
2. Gene Vaccine Protects Mice Against Development Of Her2/neu Breast Cancer
3. Development of portable infectious disease detector
4. Unexpressed But Indispensable -- The DNA Sequences That Control Development
5. UCSD-Salk Team Show Protein’s Gene-Silencing Role In Development of Nervous System
6. Analysis Of Human Genome To Predict The Development Of Illnesses
7. Study identifies predictors of HIV drug resistance in patients beginning triple therapy
8. Insight into natural cholesterol control suggests novel cholesterol-lowering therapy
9. Two chemicals boost immune cells ability to fight HIV without gene therapy
10. Elevated temperature enhances success of viral cancer therapy
11. HIV mortality in India drops with introduction of generic antiretroviral therapy
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Development gene therapy

(Date:5/18/2015)... GOTHENBURG, Sweden , May 18, 2015 ... touch fingerprint sensors FPC1020, FPC1025, FPC1145, FPC1155 and FPC1035 from ... place from June until and including Q3 2015 and the ... Asia . Communicated order values for 2015 hereby amount ... revenues for Q1 2015 of 140 MSEK and a number ...
(Date:5/11/2015)... , May 11, 2015 Curemark LLC, ... the start of a new Phase III double blind, ... its novel formulation, CM-AT, on all children ages 3-8 ... its FDA Phase III double blinded clinical trial for ... low levels of the digestive enzyme chymotrypsin. This new ...
(Date:5/5/2015)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or the "Company"), ... market, reminds investors and media that  Mr. David Tunnell ... SECURE CONNEXIONS AMERICA 2015, held in Washington DC ... conference is organized into a series of nine session tracks. ... Fraud: Where is the Trust in Cyberspace? and will ...
Breaking Biology News(10 mins):Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 230 Million and Raises Revenue Guidance for 2015 2Curemark, LLC, Launches New Phase III Trial in Expanded Population of Children with Autism 2NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 2NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 3
... new study in the July 18 issue of The ... more harmful than their unpigmented relatives. A group of ... have discovered that the molecules that give certain bugs ... cells called neutrophils. , Scientists and clinicians have known ...
... Microbiologists seeking ways to eliminate pollution from waterways with ... in freshwater ponds can generate electricity. They present their ... American Society for Microbiology. , "The bacteria are capable ... used to operate small electronic devices. As long as ...
... of that group of diseases, affects 500 000 people in ... Leishmania infantum, transmitted by sand fly bites. There is no ... if no treatment is given. In the most heavily affected ... acts as parasite reservoir for humans. Development of a vaccine ...
Cached Biology News:Pollution-eating bacteria produce electricity 2Visceral Leishmaniasis: Successful Vaccine Trial In Dogs 2Visceral Leishmaniasis: Successful Vaccine Trial In Dogs 3Visceral Leishmaniasis: Successful Vaccine Trial In Dogs 4
(Date:5/27/2015)... 2015  RXi Pharmaceuticals Corporation (NASDAQ: RXII ... developing innovative therapies primarily in the areas of ... status of the Company,s Series A and Series ... http://photos.prnewswire.com/prnh/20130917/NE80755LOGO At March ... of Series A Preferred Stock and Series A-1 ...
(Date:5/27/2015)... 27, 2015 ­ Caris Life Sciences®, a ... precision medicine, today announced it has appointed the Levine ... of excellence site in the Caris Centers of Excellence ... Cancer Institute is one of the largest cancer care ... new cancer patients annually. Derek Raghavan , M.D., ...
(Date:5/26/2015)... (PRWEB) May 26, 2015 Regenestem ... new stem cells clinic in Buenos Aires, Argentina. The ... renowned critical care specialist. Pastrana has assembled a multidisciplinary ... and orthopedics in her state-of-the-art Puerto Madero office. ... phase I to phase IV clinical studies in cellular ...
(Date:5/26/2015)... CA (PRWEB) May 26, 2015 ... and solutions in the human and animal health ... annual Vetericyn® Future Innovators of Agriculture College Scholarship ... school senior who exhibits a passionate commitment to ... , This year’s winners, Alexis Pedrow from ...
Breaking Biology Technology:RXi Pharmaceuticals Provides an Update on Series A and Series A-1 Preferred Stock 2RXi Pharmaceuticals Provides an Update on Series A and Series A-1 Preferred Stock 3Caris Life Sciences Designates Levine Cancer Institute as a Caris Center of Excellence 2Caris Life Sciences Designates Levine Cancer Institute as a Caris Center of Excellence 3Caris Life Sciences Designates Levine Cancer Institute as a Caris Center of Excellence 4Regenestem Network and Silvina Pastrana, M.D. Announce the Opening of a New Stem Cell Clinic in Buenos Aires 2Regenestem Network and Silvina Pastrana, M.D. Announce the Opening of a New Stem Cell Clinic in Buenos Aires 3Innovacyn Announces Winners Of This Year’s Vetericyn® College Scholarship Award 2Innovacyn Announces Winners Of This Year’s Vetericyn® College Scholarship Award 3
... Guide New Service Offering, PHILADELPHIA, Feb. 7 ... Alzheimer,s risk assessment service,with the appointment of a medical ... leading laboratory testing companies in the world., "Our ... accurate,information about their genetic risk, help them understand and ...
... Calif., Feb. 7 Documents,detailing the California stem ... relations firm reveal an agency,leadership worried about the ... secret by channeling it through an outside law ... said today., The stem cell institute, a ...
... In a speech to be delivered Tuesday,February 12th, ... Conference,at the New York Grand Hyatt Hotel, U.S. ... Thompson, will propose that,prevention is the solution for ... together experts from throughout the health care industry,to ...
Cached Biology Technology:Smart Genetics Announces Plans to Launch a New Alzheimer's Risk Assessment Service 2Smart Genetics Announces Plans to Launch a New Alzheimer's Risk Assessment Service 3'Crisis Management' PR Firm's Advice to Stem Cell Agency Laundered Through Law Firm to Avoid Scrutiny 2'Crisis Management' PR Firm's Advice to Stem Cell Agency Laundered Through Law Firm to Avoid Scrutiny 3U.S. Preventive Medicine National Policy Advisor Gov. Tommy Thompson to Propose Prevention is the Solution at UBS Global Health Services Conference 2
Reported to support murine B lymphocytes, hematopoietic tissue from bone marrow, B cells stimulated with lipopolysaccharide, T lymphocytes, and a variety of hybrid cells....
... Eagle's medium have been developed ... most widely used modification is ... a modification of Minimum Essential ... a higher concentration of vitamins ...
... Hollandes is a fixative useful for ... fixation. It is stable and will decalcify ... with Hollande's can be stained successfully with ... the solution stabilizes red blood cell membranes ...
... Gas Chromatograph/Mass Spectrometer, utilizing many of ... Plus, offers high throughput and excellent ... performance-to-cost ratio. Like the GCMS-QP2010 Plus, ... velocity for optimum separation, 20 temperature ...
Biology Products: