Navigation Links
Detection of DNA on nanotubes offers new sensing, sequencing technologies

Researchers at the University of Illinois at Urbana-Champaign who recently reported that DNA-wrapped carbon nanotubes could serve as sensors in living cells now say the tiny tubes can be used to target specific DNA sequences. Potential applications for the new sensors range from rapid detection of hazardous biological agents to simpler and more efficient forensic identification.

In the Jan. 27 issue of the journal Science, chemical and biomolecular engineering professor Michael Strano and his students reported that single-walled carbon nanotubes coated with DNA could be placed in living cells and detect trace amounts of harmful contaminants. In a paper accepted for publication in the journal Nano Letters, and posted on its Web site, the researchers report they have taken the technique a significant step further.

"We have successfully demonstrated the optical detection of selective DNA hybridization on the surface of a nanotube," said Strano, who is also a researcher at the Beckman Institute for Advanced Science and Technology and at the university's Micro and Nanotechnology Laboratory. "This work opens possibilities for new types of nanotube-based sensing and sequencing technologies."

In its natural state, DNA is in the double stranded form, consisting of two complementary strands, each resembling the side of a ladder and having a specific sequence of nucleotide bases as rungs. Hybridization refers to the spontaneous binding of two complementary strands through base pair matching.

By wrapping one strand of DNA around the surface of a carbon nanotube, the researchers can create a sensor that is targeted for a particular piece of complementary DNA. When the complementary DNA then binds to the DNA probe, the nanotube's natural near-infrared fluorescence is shifted slightly, and can readily be detected.

"The optical detection of specific DNA sequences through hybridization with a complementary DNA probe has many potential applicati
'"/>

Source:University of Illinois at Urbana-Champaign


Page: 1 2

Related biology news :

1. System Drastically Cuts Down Botulism Detection Time
2. Gadonanotubes greatly outperform existing MRI contrast agents
3. Modifications render carbon nanotubes nontoxic
4. Nanoparticles, nanoshells, nanotubes: How tiny specks may provide powerful tools against cancer
5. Carbon nanotubes that detect disease-causing mutations developed by Pitt researcher
6. Stable polymer nanotubes may have a biotech future
7. Pure carbon nanotubes pass first in vivo test
8. Motorola researchers develop selective sensors based on carbon nanotubes
9. Neural networking nanotubes
10. Cells selectively absorb short nanotubes
11. The longest carbon nanotubes youve ever seen
Post Your Comments:
(Date:4/17/2014)... MANHATTAN, KAN. A Kansas State University engineer ... security and remotely detects improvised explosive devices. The ... , William Dunn, the Steven M. and Kay ... of mechanical and nuclear engineering, and his research ... explosives hidden underground or in car trunks. The ...
(Date:4/17/2014)... news release is available in German . ... to pay the protection money demanded of him, he can ... seldom required, however, as fear of the consequences is enough ... observed in parasitic birds, which lay their eggs in other ... out, the brood parasites take their revenge by destroying the ...
(Date:4/17/2014)... many serious conditions such as heart disease, epilepsy and ... therapies. Unfortunately, there is still much scientists do not ... and unexpected insight into the structure of sodium channels ... - which are responsible for ,fine-tuning, the activity of ... recent edition of the Journal of Biological Chemistry ...
Breaking Biology News(10 mins):Patented research remotely detects nitrogen-rich explosives 2Fear of the cuckoo mafia 2Fear of the cuckoo mafia 3Structure of sodium channels different than previously believed 2
... in the May 2008 print issue of The FASEB ... dystrophy are missing a protein called c-FLIP, which the ... By targeting the cellular and molecular mechanisms responsible for ... stop muscle wasting from limb-girdle muscular dystrophy and other ...
... screening method for analyzing interactions between cells and ... more than half, researchers from the National Institute ... report in the new issue of Advanced Materials.* ... methods, enables rapid assessment of the biocompatibility and ...
... (WHOI) and the Bioacoustics Research Program (BRP) at the ... international energy company and federal regulators to listen for ... New England waters. Building on advances in ocean ... built and installed ten auto-detection buoys to listen for ...
Cached Biology News:Researchers discover molecular basis of a form of muscular dystrophy 2New 3-D test method for biomaterials 'flat out' faster 2New whale detection buoys will help ships take the right way through marine habitat 2New whale detection buoys will help ships take the right way through marine habitat 3
(Date:1/15/2014)... 15, 2014 More than 5 million ... 1 in 3 seniors will die with Alzheimer’s or ... jaw-dropping figures have shocked many Americans into looking for ... prevent these tragic age-related cognitive disorders. Jonathan Weisman, president ...
(Date:1/15/2014)... 2013 was a banner year of ... They saw continued independent research led by the team ... a $1 million grant from the Susanne Marcus Collins ... a peer reviewed journal, Amy Grant highlighted Brainwave Optimization® ...
(Date:1/14/2014)... (PRWEB) January 14, 2014 Date: Friday, April ... Location: Warrington Country Club, 1360 Almshouse Road, Warrington, Pa. ... nonprofit organization solely dedicated to finding a cure for hepatitis ... worldwide, will host its annual Crystal Ball on Friday, April ...
(Date:1/14/2014)... Jan. 14, 2014 As pet owners drew up their lists ... them wrote: "Take better care of my furry companion." Nowadays there ... and top-brand carrying cases to take the little canine or feline ... feel compelled to buy some pricey toys at the pet store. ...
Breaking Biology Technology:Biohack Pure Offers 5 Tips for Increasing Memory in 2014 2Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 2Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 3Hepatitis B Foundation to Host Annual Crystal Ball Gala 2New Year's Resolution: Give Pets the Gift of Top-Notch Health Care 2
... PBI-1402 did not require blood ... ... Inc.,(TSX: PLI) ("ProMetic") announces that oral PBI-1402 demonstrates,significant activity in patients ... ("RBC") transfusion., Only 2 patients out of 28 (7%) treated ...
... Contributes to First Quarter Performance; Company Taking ... Actions to Address New Challenges, ... ) today reported financial results for the first,quarter of 2008, ... (acquired in November 2007) and addressed recent,events affecting the Merck/Schering-Plough ...
... types of image are better than one for analyzing tumors ... method to determine the amount of oxygen in a tumor very ... linked to a poor outcome. A new method to do this ... time has been developed and used to image tumors in mice ...
Cached Biology Technology:Oral PBI-1402 Demonstrates Significant Activity in Chemotherapy-Induced Anemia Phase II Clinical Trial 2Oral PBI-1402 Demonstrates Significant Activity in Chemotherapy-Induced Anemia Phase II Clinical Trial 3Schering-Plough Reports Financial Results for First Quarter of 2008 2Schering-Plough Reports Financial Results for First Quarter of 2008 3Schering-Plough Reports Financial Results for First Quarter of 2008 4Schering-Plough Reports Financial Results for First Quarter of 2008 5Schering-Plough Reports Financial Results for First Quarter of 2008 6Schering-Plough Reports Financial Results for First Quarter of 2008 7Schering-Plough Reports Financial Results for First Quarter of 2008 8Schering-Plough Reports Financial Results for First Quarter of 2008 9Schering-Plough Reports Financial Results for First Quarter of 2008 10Schering-Plough Reports Financial Results for First Quarter of 2008 11Schering-Plough Reports Financial Results for First Quarter of 2008 12Schering-Plough Reports Financial Results for First Quarter of 2008 13Schering-Plough Reports Financial Results for First Quarter of 2008 14Schering-Plough Reports Financial Results for First Quarter of 2008 15Schering-Plough Reports Financial Results for First Quarter of 2008 16Schering-Plough Reports Financial Results for First Quarter of 2008 17Schering-Plough Reports Financial Results for First Quarter of 2008 18Schering-Plough Reports Financial Results for First Quarter of 2008 19JCI table of contents: April 22, 2008 2JCI table of contents: April 22, 2008 3JCI table of contents: April 22, 2008 4JCI table of contents: April 22, 2008 5JCI table of contents: April 22, 2008 6JCI table of contents: April 22, 2008 7JCI table of contents: April 22, 2008 8JCI table of contents: April 22, 2008 9JCI table of contents: April 22, 2008 10JCI table of contents: April 22, 2008 11JCI table of contents: April 22, 2008 12
Fast, sensitive quantitation of Mouse IgM concentration....
... vial contains 200 g of lyophilized peptide ... (C-terminal amino acids 380-402; GLTPSAWEASSLRSSRHSGLSHF. ... for production of Cayman's EP1 receptor polyclonal ... used in conjunction with this antibody to ...
... x 25 mm; approximately 1 mm thick, ... sections, sandblasted frosted writing ... markings will not rub off or wash off ... store at room temperature ...
Complete cell culture media with cytokines...
Biology Products: