Navigation Links
'Dating agency' boosts hunt for disease genes

Doctors and scientists nationwide will today for the first time be able to join together over the internet to start the search for genes that underlie a range of chronic diseases.

Patients across Britain with cancer, heart and other common diseases have been providing blood samples for research since 2000. They are part of a project hosted by The University of Manchester that will allow more researchers than ever before to study genes in chronic diseases. The project - called the UK DNA Banking Network - was initiated in 1999 as a scientific infrastructure with government funding via the Medical Research Council.

"The infrastructure is already up and running for handling patient samples. Now what we've done is to create a sort of scientists' dating agency and shop," explains the Director of the Network's archive, Dr Martin Yuille (University of Manchester). "Vetted scientists can find on the website both data and materials about a disease. Then, they can 'date' a collaborator, design an experiment together and make an online wish list of patients' DNAs that they need."

The DNA Network provides web access by registered researchers to detailed summaries of data on patients whose anonymity is assured. The researchers hone their hypotheses in collaboration with the clinicians who are the custodians of the samples provided by patients. The new collaborators then request top quality research materials from the DNA Network's archive.

"The significance of this development is that it builds on the success of the Human Genome Project. This discovered all our genes - and revealed that biologists now need serious logistics for this type of research," says Dr Yuille. "The UK DNA Banking Network is leading the world in providing a sample and data infrastructure to tackle the challenge of uncovering the genetic pathways of complex disease."

Dr Kate Dixon, who manages the archive at the Centre for Integrated Genomic Medical Research (CIGMR ) at The University of Manchester, adds: "The archive manages tens of thousands of samples for a dozen diseases. Now we are using the internet to sort out the logistics of distribution."

Simon Pullum, the chief executive of Azura Group, a technology consultancy in Essex used by the DNA Network, says: "The software is designed to be compatible with any database architecture. This will help the scientists bring in more collaborators and more data types."

The website is at www.dna-network.ac.uk.

The UK clinicians in the Network are experts in gut, breast and white blood cell cancers, heart attacks and high blood pressure, depression, diabetes, kidney disease, multiple sclerosis, Parkinson's and Alzheimer's diseases, old age blindness, childhood asthma and eczema. The clinicians leading each national disease collection are based in London, Exeter, Cardiff, Oxford, Cambridge, Birmingham, Leeds, Edinburgh and Aberdeen.

Samples and data are managed at a robotic archive in the University of Manchester and in the Health Protection Agency's European Collection of Cell Cultures labs in Salisbury.


'"/>

Source:University of Manchester


Related biology news :

1. Combination therapy boosts effectiveness of telomere-directed cancer cell death
2. Crickets finicky mating behavior boosts biodiversity
3. Lance Armstrong through a physiological lens: hard training boosts muscle power 8%
4. Discovery of T-cell traffic control boosts new drug promise
5. Good news for the medical marijuana movement: pot proliferates brain cells and boosts mood
6. Just the expectation of a mirthful laughter experience boosts endorphins 27 percent, HGH 87 percent
7. Breastfeeding boosts mental health
8. A natural chemical found in strawberries boosts memory in healthy mice
9. Queen bee promiscuity boosts hive health
10. New technique boosts size of proteins that can be analyzed
11. Eating protein boosts hormone that staves off hunger
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/21/2016)... 22, 2016 Unique technology ... for superior security   Xura, ... of secure digital communications services, today announced it is ... offer enterprise customers, particularly those in the Financial Services ... voice authentication within a mobile app, alongside, and in ...
(Date:3/15/2016)... , March 15, 2016 --> ... published by Transparency Market Research "Digital Door Lock Systems Market ... 2015 - 2023," the global digital door lock systems market ... in 2014 and is forecast to grow at a CAGR ... micro, small and medium enterprises (MSMEs) across the world and ...
(Date:3/14/2016)... , Allemagne, March 14, 2016 ... ) - --> - Renvoi : image ... --> --> ... biométriques, fournit de nouveaux lecteurs d,empreintes digitales pour ... de DERMALOG sera utilisé pour produire des cartes ...
Breaking Biology News(10 mins):
(Date:5/31/2016)... ... 2016 , ... Doctors in Italy say mesothelioma patients with the highest levels ... levels. Surviving Mesothelioma has just posted an article on the new research. Click ... La Spezia, Italy tested the blood serum, tumors, and lung fluid of 45 ...
(Date:5/31/2016)... ... May 31, 2016 , ... The Academy of Model Aeronautics is thrilled ... on display Memorial Day through Labor Day 2016. Bill Chaffee’s Boeing P-12B will be ... , Bill Chaffee won first place for Senior Scale Model at the 1930 National ...
(Date:5/27/2016)... ... May 27, 2016 , ... Weeks after hosting a ... Phoenix, Dr. Michael Fitzmaurice, hand surgeon and founder of the Fitzmaurice Hand Institute, has ... Wrist MRI machine is a state-of-the-art technology and only 1 of about 3 currently ...
(Date:5/27/2016)... ... ... Doctors in Italy, Japan, the UK and the US have reached some surprising ... its link to malignant mesothelioma. Surviving Mesothelioma has just posted the details of their ... , The studies analyzed for the new report included more than 3,447 cancer patients. ...
Breaking Biology Technology: