Navigation Links
'Dating agency' boosts hunt for disease genes

Doctors and scientists nationwide will today for the first time be able to join together over the internet to start the search for genes that underlie a range of chronic diseases.

Patients across Britain with cancer, heart and other common diseases have been providing blood samples for research since 2000. They are part of a project hosted by The University of Manchester that will allow more researchers than ever before to study genes in chronic diseases. The project - called the UK DNA Banking Network - was initiated in 1999 as a scientific infrastructure with government funding via the Medical Research Council.

"The infrastructure is already up and running for handling patient samples. Now what we've done is to create a sort of scientists' dating agency and shop," explains the Director of the Network's archive, Dr Martin Yuille (University of Manchester). "Vetted scientists can find on the website both data and materials about a disease. Then, they can 'date' a collaborator, design an experiment together and make an online wish list of patients' DNAs that they need."

The DNA Network provides web access by registered researchers to detailed summaries of data on patients whose anonymity is assured. The researchers hone their hypotheses in collaboration with the clinicians who are the custodians of the samples provided by patients. The new collaborators then request top quality research materials from the DNA Network's archive.

"The significance of this development is that it builds on the success of the Human Genome Project. This discovered all our genes - and revealed that biologists now need serious logistics for this type of research," says Dr Yuille. "The UK DNA Banking Network is leading the world in providing a sample and data infrastructure to tackle the challenge of uncovering the genetic pathways of complex disease."

Dr Kate Dixon, who manages the archive at the Centre for Integrated Genomic Medical Research (CIGMR ) at The University of Manchester, adds: "The archive manages tens of thousands of samples for a dozen diseases. Now we are using the internet to sort out the logistics of distribution."

Simon Pullum, the chief executive of Azura Group, a technology consultancy in Essex used by the DNA Network, says: "The software is designed to be compatible with any database architecture. This will help the scientists bring in more collaborators and more data types."

The website is at www.dna-network.ac.uk.

The UK clinicians in the Network are experts in gut, breast and white blood cell cancers, heart attacks and high blood pressure, depression, diabetes, kidney disease, multiple sclerosis, Parkinson's and Alzheimer's diseases, old age blindness, childhood asthma and eczema. The clinicians leading each national disease collection are based in London, Exeter, Cardiff, Oxford, Cambridge, Birmingham, Leeds, Edinburgh and Aberdeen.

Samples and data are managed at a robotic archive in the University of Manchester and in the Health Protection Agency's European Collection of Cell Cultures labs in Salisbury.


'"/>

Source:University of Manchester


Related biology news :

1. Combination therapy boosts effectiveness of telomere-directed cancer cell death
2. Crickets finicky mating behavior boosts biodiversity
3. Lance Armstrong through a physiological lens: hard training boosts muscle power 8%
4. Discovery of T-cell traffic control boosts new drug promise
5. Good news for the medical marijuana movement: pot proliferates brain cells and boosts mood
6. Just the expectation of a mirthful laughter experience boosts endorphins 27 percent, HGH 87 percent
7. Breastfeeding boosts mental health
8. A natural chemical found in strawberries boosts memory in healthy mice
9. Queen bee promiscuity boosts hive health
10. New technique boosts size of proteins that can be analyzed
11. Eating protein boosts hormone that staves off hunger
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/14/2017)... WINSTON-SALEM, N.C. , Feb. 14, 2017  Wake ... FRY-shlog), M.D., as its new chief executive officer (CEO). ... succeeds CEO John D. McConnell , M.D., who ... new position at the Medical Center, after leading it ... oversee the full scope of Wake Forest Baptist,s academic ...
(Date:2/10/2017)... -- Research and Markets has announced the ... Scientific and Commercial Aspects" to their offering. ... Biomarkers play ... therapy for selection of treatment as well for monitoring the ... disease in modern medicine. Biochip/microarray technologies and next generation sequencing ...
(Date:2/8/2017)... (NASDAQ: AWRE ), a leading supplier of biometrics ... and year ended December 31, 2016. Revenue ... to $6.9 million in the same quarter last year. Operating ... compared to $2.6 million in the fourth quarter of 2015. ... million, or $0.02 per diluted share, which compares to $1.8 ...
Breaking Biology News(10 mins):
(Date:2/20/2017)... , ... February 20, 2017 , ... ... the re-launch of “Crosswalk Insight: Oncology™” (Crosswalk), a unique precision medicine knowledge visualization ... can now be accessed through Inspirata’s diagnostic cockpit and is downloadable as an ...
(Date:2/20/2017)... ... February 20, 2017 , ... PuraCath ... associated with peritoneal dialysis, announced today that it has published the result of ... in Peritoneal Dialysis International (PDI), the official Journal of the International Society ...
(Date:2/20/2017)...  Atrius Health and IBM (NYSE: IBM ... to develop a cloud based service designed to ... view of the multiple influences on an individual,s ... be designed to support shared decision making between ... nonprofit healthcare organization with 875 physicians caring for ...
(Date:2/18/2017)... ... February 17, 2017 , ... The BMT ... the Center for International Blood & Marrow Transplant Research (CIBMTR) will take place ... , The combined scientific sessions offer investigators, clinicians, laboratory technicians, clinical research ...
Breaking Biology Technology: