Navigation Links
Dartmouth study finds that arsenic inhibits DNA repair

Dartmouth researchers, working with scientists at the University of Arizona and at the Department of Natural Resources in Sonora, Mexico, have published a study on the impact of arsenic exposure on DNA damage. They have determined that arsenic in drinking water is associated with a decrease in the body's ability to repair its DNA.

"This work supports the idea that arsenic in drinking water can promote the carcinogenic effects of other chemicals," says Angeline Andrew, the lead author and a research assistant professor of community and family medicine at Dartmouth Medical School. "This is evidence that it's more important than ever to keep arsenic out of drinking water."

The study, which was published online on May 10, 2006, in the journal Environmental Health Perspectives, examined the drinking water and measured the arsenic levels in samples of urine and toenails of people who were enrolled in epidemiologic studies in New Hampshire, and in Sonora, Mexico.

Andrew and her colleagues examined the data in conjunction with tissue samples from the study participants to determine the effect of arsenic on DNA repair. To further corroborate their findings, the researchers conducted laboratory studies to examine the effects of arsenic on DNA repair in cultured human cell models.

"The DNA repair machinery normally protects us from DNA-damaging agents, such as those found in cigarette smoke," says Andrew. "The concern is that exposure to drinking water arsenic may exacerbate the harmful effects of smoking or other exposures."

Andrew explains that in regions of the United States where the rock contains higher levels of arsenic, the greater the likelihood that drinking water sources contain some potential adverse levels of the toxin. While the levels of arsenic in municipal water systems are regularly monitored, there is no mandated testing of arsenic levels in private wells. This is of particular concern since the regions where arsenic
'"/>

Source:Dartmouth College


Page: 1 2

Related biology news :

1. GlycoFi and Dartmouth report full humanization of yeast glycosylation pathway in Science
2. Bioartificial kidney under study at MCG
3. W.M. Keck Foundation funds study of friendly microbes
4. Yellowstone microbes fueled by hydrogen, according to U. of Colorado study
5. Genome-wide mouse study yields link to human leukemia
6. Clam embryo study shows pollutant mixture adversely affects nerve cell development
7. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
8. Same mutation aided evolution in many fish species, Stanford study finds
9. Sequencing of marine bacterium will help study of cell communication
10. Genetically modified rice in China benefits farmers health, study finds
11. A new study examines how shared pathogens affect host populations
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Dartmouth study finds that arsenic inhibits DNA repair

(Date:8/27/2014)... NY (June, 2014) Outstanding basic research, a ... a dedication to patient care have earned the ... University Medical Center (CUMC) and NewYork-Presbyterian Hospital an ... the National Cancer Institute (NCI). The grant renews ... NCI-designated Comprehensive Cancer Centers in New York City ...
(Date:8/27/2014)... number of studies have shown that excessive ... of Parkinson,s disease. Previous studies from Chunyan ... in China have shown that baicalin prevented ... divalent metal transporter 1 expression, and increased ... of rotenone-induced Parkinson,s disease rats. However, the ...
(Date:8/27/2014)... of seven hours ago the Happy Camp Complex of ... California, the July complex had consumed 35,530 as of ... fires on the Happy Camp Ranger District of the ... area on August 11, 2014. All but three of ... is a list of contained fires and their size ...
Breaking Biology News(10 mins):Herbert Irving Comprehensive Cancer Center awarded $18 million grant 2Herbert Irving Comprehensive Cancer Center awarded $18 million grant 3Herbert Irving Comprehensive Cancer Center awarded $18 million grant 4Happy Camp and July Fire Complexes in California 2
... your body is telling you that your pace feels a little ... A new study, published online March 18 in the ... human running varies with speed and that each individual has an ... distance with the least effort. The result debunks the ...
... millions of people with diseases that starve eye tissue ... procedure being developed by researchers at Oak Ridge National ... of Tennessee. The technique uses a new class ... tissue being deprived of oxygen because of restricted blood ...
... of the benefits of cooling strategies to protect the ... to a wealth of cutting edge research, prime examples ... of Journal of Neurotrauma , a peer-reviewed journal ... The issue will be available free online at ...
Cached Biology News:Optimum running speed is stride toward understanding human body form 2ORNL, Southern Cal set sights on preventing blindness 2Therapeutic hypothermia is promising strategy to minimize tissue damage 2
(Date:8/28/2014)... , Aug. 28, 2014  Armetheon, Inc. ( ... novel mid- to late-stage cardiovascular drug candidates, today ... its first round of financing. The Series A ... Hercules Bioventures with participation from investors that included ... executive, Dr. Larry Hsu , the founder ...
(Date:8/28/2014)... USA (PRWEB) August 27, 2014 Scientists, ... month for SPIE Laser Damage 2014 symposium. ... materials for high-power lasers will run 14-17 September. The ... for optics and photonics . , The premier conference ... understanding laser damage to optical materials will engage researchers ...
(Date:8/28/2014)... Earlier this month, a report ... with the U.S. Air Force on the performance of ... that this type of fuel made from mustard seeds, ... important to America’s Eco friendly future. In fact, every ... to become independent of foreign oil over the next ...
(Date:8/28/2014)... 28, 2014 Supplementing their complete ... promotion for Eppendorf Safe Lock Centrifuge Tubes ... the highest quality tubes at an affordable price. ... customers doing chemical, medical, pharmaceutical, and life science ... not regularly able to afford Eppendorf products. , ...
Breaking Biology Technology:Armetheon Completes $7.0 Million Series A Financing 2Armetheon Completes $7.0 Million Series A Financing 3Laser Damage to Draw Researchers, Engineers, Scientists to 46th Annual Conference 2Laser Damage to Draw Researchers, Engineers, Scientists to 46th Annual Conference 3Can Small Farmers and a New Seed Based Biofuel “Green” the World? Major Universities and Even the U.S. Air Force Seem to Think So 2Can Small Farmers and a New Seed Based Biofuel “Green” the World? Major Universities and Even the U.S. Air Force Seem to Think So 3Can Small Farmers and a New Seed Based Biofuel “Green” the World? Major Universities and Even the U.S. Air Force Seem to Think So 4Can Small Farmers and a New Seed Based Biofuel “Green” the World? Major Universities and Even the U.S. Air Force Seem to Think So 5Eppendorf Safe Lock Centrifuge Tube Promotion Now Available at Major Pipette Distributor Pipette.com 2Eppendorf Safe Lock Centrifuge Tube Promotion Now Available at Major Pipette Distributor Pipette.com 3
... N.J., July 21 BioNeutral Group, Inc. ("BioNeutral") (OTC ... Science Company announced today that at ATS Labs using ... Antimicrobial passed the difficult Quantitative Disk Carrier test ... difficile (C.diff) present in this test ...
... , , PALO ALTO, Calif., July 21, ... third quarter of its fiscal year 2009 after 1:00 p.m. Pacific Time ... of its investor conference call to review those quarterly results is scheduled ... , That live webcast can be accessed from Varian, ...
... , , KENILWORTH, N.J., July 21 ... for the 2009 second quarter. , , ... given us the strength to again power through tough challenges - delivering ... Fred Hassan, chairman and CEO. , , ...
Cached Biology Technology:BioNeutral's Ygiene(TM) Hospital Grade Achieves a 100% Total Kill (Pass) Against the Life Threatening Clostridium Difficile (C.diff) Spores in Independent EPA Required Protocol Testing. 2BioNeutral's Ygiene(TM) Hospital Grade Achieves a 100% Total Kill (Pass) Against the Life Threatening Clostridium Difficile (C.diff) Spores in Independent EPA Required Protocol Testing. 3Schering-Plough Reports Financial Results for 2009 Second Quarter 2Schering-Plough Reports Financial Results for 2009 Second Quarter 3Schering-Plough Reports Financial Results for 2009 Second Quarter 4Schering-Plough Reports Financial Results for 2009 Second Quarter 5Schering-Plough Reports Financial Results for 2009 Second Quarter 6Schering-Plough Reports Financial Results for 2009 Second Quarter 7Schering-Plough Reports Financial Results for 2009 Second Quarter 8Schering-Plough Reports Financial Results for 2009 Second Quarter 9Schering-Plough Reports Financial Results for 2009 Second Quarter 10Schering-Plough Reports Financial Results for 2009 Second Quarter 11Schering-Plough Reports Financial Results for 2009 Second Quarter 12Schering-Plough Reports Financial Results for 2009 Second Quarter 13Schering-Plough Reports Financial Results for 2009 Second Quarter 14Schering-Plough Reports Financial Results for 2009 Second Quarter 15Schering-Plough Reports Financial Results for 2009 Second Quarter 16Schering-Plough Reports Financial Results for 2009 Second Quarter 17Schering-Plough Reports Financial Results for 2009 Second Quarter 18Schering-Plough Reports Financial Results for 2009 Second Quarter 19Schering-Plough Reports Financial Results for 2009 Second Quarter 20Schering-Plough Reports Financial Results for 2009 Second Quarter 21Schering-Plough Reports Financial Results for 2009 Second Quarter 22Schering-Plough Reports Financial Results for 2009 Second Quarter 23Schering-Plough Reports Financial Results for 2009 Second Quarter 24Schering-Plough Reports Financial Results for 2009 Second Quarter 25Schering-Plough Reports Financial Results for 2009 Second Quarter 26Schering-Plough Reports Financial Results for 2009 Second Quarter 27
... 25-Hydroxy Vitamin D kit is an ... of 25-hydroxyvitamin D (25-OH D) and ... or plasma. Our patented DIRECT assay ... precipitation and centrifugation and therefore facilitates ...
... The IDS Corticosterone kit is a competitive ... corticosterone in mouse or rat serum or ... sole, corticosteroid in rats and mice, and ... birds and reptiles. Most mammals produce both ...
Mouse monoclonal [BC-4] to Aggrecan xxPEN ( Abpromise for all tested applications). entrezGeneID: 176 SwissProtID: P16112...
Mouse monoclonal [1.F.1] to Yersinia pestis F1 antigen ( Abpromise for all tested applications). Antigen: Purified F1 antigen of Y. pestis vaccine strain EB....
Biology Products: