( seful in identifying potential function...)DOE JGI launches IMG public online microbial genome data clearinghouse

seful in identifying potential functions for hypothetical genes that we find upregulated in Caulobacter crescentus strains exposed to heavy metals. Examining the neighborhood around a gene of unknown function in multiple species selected from the organism browser may yield clues of what its role might be in your particular species," said Andersen. "The interface is quite intuitive, which is a benefit for someone like me that does not like to read manuals."

John Taylor, professor of plant and microbial biology at UC Berkeley, tried out the IMG system at a community workshop in February. "In evolutionary biology, comparative genomics has become the most powerful tool for understanding everything from the patterns of mutation to adaptation," said Taylor. "Computational biologists have led the way, but IMG makes it possible for evolutionary biologists without first-rate computer skills to compare fungal and bacterial genomes and scrutinize fundamental processes like speciation and adaptation."

In addition to curating the IMG system, DOE JGI will continue to deposit genome sequence information it generates into GenBank®, the repository maintained by the National Center for Biotechnology Information.

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To familiarize the user community with the IMG system, a series of IMG presentations will be offered in various locations during March and April. The schedule is available at http://img.jgi.doe.gov/v1.0/news/presentations.html.

The DOE Joint Genome Institute, supported primarily by the DOE Office of Science, is among the world leaders in whole-genome sequencing projects devoted to microbes and microbial communities, model system vertebrates, aquatic organisms, and plants. Established in 1997, DOE JGI now unites the expertise of four national laboratories, Lawrence Berkeley, Lawrence Livermore, Los Alamos, and Oak Ridge, along with the Stanford Human Genome Center to advance the frontiers of genome sequencing and related biology. Add
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Source:DOE/Joint Genome Institute

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